| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the thiostrepton-4563 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ANTXR1 | anthrax toxin receptor 1 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATF3 | activating transcription factor 3 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 |
| CADM3 | cell adhesion molecule 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNTNAP2 | contactin associated protein-like 2 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYTH4 | cytohesin 4 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIDO1 | death inducer-obliterator 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DYM | dymeclin |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FGB | fibrinogen beta chain |
| FLJ11292 | |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HGFAC | HGF activator |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB8 | heat shock 22kDa protein 8 |
| IL4 | interleukin 4 |
| INSIG1 | insulin induced gene 1 |
| JPH3 | junctophilin 3 |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KLHL20 | kelch-like family member 20 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT31 | keratin 31, type I |
| KRT33A | keratin 33A, type I |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MYBPC3 | myosin binding protein C, cardiac |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NFIB | nuclear factor I/B |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUP160 | nucleoporin 160kDa |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDCD2 | programmed cell death 2 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RBM34 | RNA binding motif protein 34 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RETN | resistin |
| RGCC | regulator of cell cycle |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RND1 | Rho family GTPase 1 |
| RPS3A | ribosomal protein S3A |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO1B1 | solute carrier organic anion transporter family, member 1B1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| STK3 | serine/threonine kinase 3 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VLDLR | very low density lipoprotein receptor |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADCY6 | adenylate cyclase 6 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CENPB | centromere protein B, 80kDa |
| CEP112 | centrosomal protein 112kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CLEC16A | C-type lectin domain family 16, member A |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| FADD | Fas (TNFRSF6)-associated via death domain |
| FAM131B | family with sequence similarity 131, member B |
| FAM50B | family with sequence similarity 50, member B |
| FANCF | Fanconi anemia, complementation group F |
| FJX1 | four jointed box 1 (Drosophila) |
| FZD8 | frizzled class receptor 8 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR87 | G protein-coupled receptor 87 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| H1F0 | H1 histone family, member 0 |
| HAS2 | hyaluronan synthase 2 |
| HOXC8 | homeobox C8 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KRCC1 | lysine-rich coiled-coil 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC6 | leucine rich repeat containing 6 |
| MAVS | mitochondrial antiviral signaling protein |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NIT1 | nitrilase 1 |
| NLRX1 | NLR family member X1 |
| NME5 | NME/NM23 family member 5 |
| NMRK1 | nicotinamide riboside kinase 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLAT | plasminogen activator, tissue |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| RWDD2B | RWD domain containing 2B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| STK16 | serine/threonine kinase 16 |
| STON1 | stonin 1 |
| SYTL2 | synaptotagmin-like 2 |
| TENM4 | teneurin transmembrane protein 4 |
| TERF2 | telomeric repeat binding factor 2 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TRIM66 | tripartite motif containing 66 |
| TRIM9 | tripartite motif containing 9 |
| TRIOBP | TRIO and F-actin binding protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3C | tubulin, alpha 3c |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF32 | zinc finger protein 32 |
| ZNF629 | zinc finger protein 629 |
| ZNF667 | zinc finger protein 667 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
