tho complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits. (Gene Ontology, GO_0000347)
Similar Terms
Downloads & Tools

Genes

28 proteins co-occuring with the tho complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
THOC5 THO complex 5 2.81241
THOC7 THO complex 7 1.91465
THOC2 THO complex 2 1.82321
SARNP SAP domain containing ribonucleoprotein 1.68421
THOC1 THO complex 1 1.56219
THOC6 THO complex 6 1.45477
ENY2 enhancer of yellow 2 homolog (Drosophila) 1.42824
NXF1 nuclear RNA export factor 1 1.35047
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 1.03328
MED10 mediator complex subunit 10 1.00448
ZCCHC7 zinc finger, CCHC domain containing 7 0.903673
NUTF2 nuclear transport factor 2 0.802021
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.740965
ALYREF Aly/REF export factor 0.580922
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B 0.569664
RAE1 ribonucleic acid export 1 0.563017
HSPA4 heat shock 70kDa protein 4 0.502288
GLI2 GLI family zinc finger 2 0.499042
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.494585
TOP1 topoisomerase (DNA) I 0.398199
AICDA activation-induced cytidine deaminase 0.384665
PTK2 protein tyrosine kinase 2 0.344178
UBE2H ubiquitin-conjugating enzyme E2H 0.242076
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.178011
LGALS4 lectin, galactoside-binding, soluble, 4 0.168349
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.165
CXCL12 chemokine (C-X-C motif) ligand 12 0.160658
PTPRD protein tyrosine phosphatase, receptor type, D 0.156688