thrombopoietin Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	Thrombopoietin (THPO) also known as megakaryocyte growth and development factor (MGDF) is a protein that in humans is encoded by the THPO gene. Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.[1] (Experimental Factor Ontology, EFO_0003236)
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Genes

19 genes co-occuring with the biological term thrombopoietin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
CSF2	colony stimulating factor 2 (granulocyte-macrophage)
EPO	erythropoietin
FLT3	fms-related tyrosine kinase 3
FLT3LG	fms-related tyrosine kinase 3 ligand
GATA1	GATA binding protein 1 (globin transcription factor 1)
GP1BA	glycoprotein Ib (platelet), alpha polypeptide
GP6	glycoprotein VI (platelet)
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)
HOXA9	homeobox A9
IL11	interleukin 11
IL1B	interleukin 1, beta
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
MKL1	megakaryoblastic leukemia (translocation) 1
MPL	MPL proto-oncogene, thrombopoietin receptor
MTOR	mechanistic target of rapamycin (serine/threonine kinase)
NUDC	nudC nuclear distribution protein
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
THPO	thrombopoietin
TPO	thyroid peroxidase