thymoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus. (Human Disease Ontology, DOID_3275)
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Genes

308 genes co-occuring with the disease thymoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TTN titin 1.94407
MUSK muscle, skeletal, receptor tyrosine kinase 1.67186
DPYSL5 dihydropyrimidinase-like 5 1.55912
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.54937
RYR1 ryanodine receptor 1 (skeletal) 1.51765
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 1.50096
CD4 CD4 molecule 1.46847
CD5 CD5 molecule 1.39914
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.39826
IL2 interleukin 2 1.3337
THY1 Thy-1 cell surface antigen 1.3027
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.16179
AIRE autoimmune regulator 1.15155
STK16 serine/threonine kinase 16 1.14815
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) 1.07068
AMPH amphiphysin 1.05345
NMT1 N-myristoyltransferase 1 1.01723
LRP4 low density lipoprotein receptor-related protein 4 0.967502
DPYSL4 dihydropyrimidinase-like 4 0.960797
NMS neuromedin S 0.95996
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.943274
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.942858
TRAC T cell receptor alpha constant 0.917199
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.907731
OMG oligodendrocyte myelin glycoprotein 0.870415
LDHB lactate dehydrogenase B 0.814693
EGFR epidermal growth factor receptor 0.74883
HLA-B major histocompatibility complex, class I, B 0.745578
B3GAT1 beta-1,3-glucuronyltransferase 1 0.739488
KRT5 keratin 5, type II 0.738676
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.729357
ACHE acetylcholinesterase (Yt blood group) 0.728952
LGI1 leucine-rich, glioma inactivated 1 0.724098
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.714408
MNT MAX network transcriptional repressor 0.713601
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.699116
PNMA2 paraneoplastic Ma antigen 2 0.695504
ZBTB7B zinc finger and BTB domain containing 7B 0.694301
PDCD7 programmed cell death 7 0.668742
DOK7 docking protein 7 0.665166
BCHE butyrylcholinesterase 0.656441
TP53 tumor protein p53 0.653671
PTEN phosphatase and tensin homolog 0.648533
CD99 CD99 molecule 0.647348
CD7 CD7 molecule 0.638282
MTCH1 mitochondrial carrier 1 0.624143
PTPRC protein tyrosine phosphatase, receptor type, C 0.617877
SMAD1 SMAD family member 1 0.617094
DHDH dihydrodiol dehydrogenase (dimeric) 0.616703
CD34 CD34 molecule 0.61162
MMP10 matrix metallopeptidase 10 0.611229
CD58 CD58 molecule 0.608104
ARHGAP44 Rho GTPase activating protein 44 0.606543
LCK LCK proto-oncogene, Src family tyrosine kinase 0.605372
HLA-E major histocompatibility complex, class I, E 0.604981
DSG3 desmoglein 3 0.604591
FOXO1 forkhead box O1 0.604201
BRAF B-Raf proto-oncogene, serine/threonine kinase 0.584719
IL1A interleukin 1, alpha 0.578494
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.571107
MAPK3 mitogen-activated protein kinase 3 0.566054
DAP3 death associated protein 3 0.565666
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.550522
SYP synaptophysin 0.547419
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.547419
CNTNAP2 contactin associated protein-like 2 0.544705
DNTT DNA nucleotidylexotransferase 0.540829
TMSB4X thymosin beta 4, X-linked 0.540055
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.539667
RAD17 RAD17 homolog (S. pombe) 0.538118
IL5 interleukin 5 0.532701
NKX2-1 NK2 homeobox 1 0.532314
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.529608
CD79A CD79a molecule, immunoglobulin-associated alpha 0.522659
CD28 CD28 molecule 0.522659
HRAS Harvey rat sarcoma viral oncogene homolog 0.520346
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.509192
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.504207
CD19 CD19 molecule 0.499614
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.497321
TRIB3 tribbles pseudokinase 3 0.492359
CAMP cathelicidin antimicrobial peptide 0.48893
INS insulin 0.48893
NPB neuropeptide B 0.488169
PRSS16 protease, serine, 16 (thymus) 0.484364
CD48 CD48 molecule 0.483985
CAPN7 calpain 7 0.483985
CD69 CD69 molecule 0.483604
IRS2 insulin receptor substrate 2 0.481325
SNED1 sushi, nidogen and EGF-like domains 1 0.469576
HAVCR2 hepatitis A virus cellular receptor 2 0.468819
CALB2 calbindin 2 0.461639
INSR insulin receptor 0.460129
FOXN1 forkhead box N1 0.458996
RGS3 regulator of G-protein signaling 3 0.456732
SST somatostatin 0.447687
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.446558
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.445805
MEN1 multiple endocrine neoplasia I 0.444676
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.440162
VNN2 vanin 2 0.437154
SC5D sterol-C5-desaturase 0.436778
CEMP1 cementum protein 1 0.436026
PPL periplakin 0.432646
LMF1 lipase maturation factor 1 0.43227
SRRM1 serine/arginine repetitive matrix 1 0.428516
TMX1 thioredoxin-related transmembrane protein 1 0.426265
SYT1 synaptotagmin I 0.425139
EVPL envoplakin 0.42364
CD40 CD40 molecule, TNF receptor superfamily member 5 0.422515
MUC15 mucin 15, cell surface associated 0.417644
CHGA chromogranin A 0.412031
GMFB glia maturation factor, beta 0.408666
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 0.405678
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.405678
LPXN leupaxin 0.405678
SOX1 SRY (sex determining region Y)-box 1 0.405305
PHYH phytanoyl-CoA 2-hydroxylase 0.405305
ALPPL2 alkaline phosphatase, placental-like 2 0.397098
IL1B interleukin 1, beta 0.39598
IFNA1 interferon, alpha 1 0.395235
CYS1 cystin 1 0.393001
RAPSN receptor-associated protein of the synapse 0.391885
PAX8 paired box 8 0.386679
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.384079
MSC musculin 0.382223
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 0.381481
PLEK pleckstrin 0.380368
PTPRA protein tyrosine phosphatase, receptor type, A 0.378885
PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.378514
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.37629
CST7 cystatin F (leukocystatin) 0.37592
CALCA calcitonin-related polypeptide alpha 0.370368
AKAP4 A kinase (PRKA) anchor protein 4 0.369258
CXCR5 chemokine (C-X-C motif) receptor 5 0.369258
ALPP alkaline phosphatase, placental 0.366301
ALPL alkaline phosphatase, liver/bone/kidney 0.365932
EFNA2 ephrin-A2 0.364085
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.362978
TBC1D4 TBC1 domain family, member 4 0.362609
IRS1 insulin receptor substrate 1 0.362239
MDM4 MDM4, p53 regulator 0.360026
POMC proopiomelanocortin 0.358551
CD8A CD8a molecule 0.357446
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.355235
HLA-A major histocompatibility complex, class I, A 0.353395
SLC38A4 solute carrier family 38, member 4 0.352659
JUN jun proto-oncogene 0.351923
GABPB1 GA binding protein transcription factor, beta subunit 1 0.348981
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.348246
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit 0.344941
DSG1 desmoglein 1 0.340906
CD38 CD38 molecule 0.338341
ZNF185 zinc finger protein 185 (LIM domain) 0.335778
ENO2 enolase 2 (gamma, neuronal) 0.333949
SGK3 serum/glucocorticoid regulated kinase family, member 3 0.333949
MMP11 matrix metallopeptidase 11 0.32993
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.329565
IL4 interleukin 4 0.324458
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.324094
KRAS Kirsten rat sarcoma viral oncogene homolog 0.320817
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.32009
SYT2 synaptotagmin II 0.317909
NKX6-1 NK6 homeobox 1 0.317909
DNER delta/notch-like EGF repeat containing 0.315729
RND1 Rho family GTPase 1 0.313189
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.301976
MTA2 metastasis associated 1 family, member 2 0.300894
TG thyroglobulin 0.300173
DYNLT1 dynein, light chain, Tctex-type 1 0.299092
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.295492
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.290821
ATL2 atlastin GTPase 2 0.290103
STIM1 stromal interaction molecule 1 0.28616
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.283655
AQP4 aquaporin 4 0.28294
BCL2 B-cell CLL/lymphoma 2 0.280082
GIN1 gypsy retrotransposon integrase 1 0.27794
HAS2 hyaluronan synthase 2 0.276158
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.273664
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.272241
TFRC transferrin receptor 0.27153
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.269398
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.265494
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.265494
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.263368
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.261599
CD247 CD247 molecule 0.261245
DEPTOR DEP domain containing MTOR-interacting protein 0.260538
SALL4 spalt-like transcription factor 4 0.259477
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.257711
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.256652
GZMK granzyme K (granzyme 3; tryptase II) 0.253127
CRMP1 collapsin response mediator protein 1 0.252422
FOXP3 forkhead box P3 0.25207
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.250311
PPARG peroxisome proliferator-activated receptor gamma 0.250311
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.249608
STPG1 sperm-tail PG-rich repeat containing 1 0.248905
ERBB2 erb-b2 receptor tyrosine kinase 2 0.246448
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.245747
CD86 CD86 molecule 0.245046
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.243645
FYN FYN proto-oncogene, Src family tyrosine kinase 0.240847
SPATA21 spermatogenesis associated 21 0.23666
ITCH itchy E3 ubiquitin protein ligase 0.236312
RAD51B RAD51 paralog B 0.235616
OAT ornithine aminotransferase 0.234225
HDLBP high density lipoprotein binding protein 0.232836
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.232142
KRT7 keratin 7, type II 0.229716
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.227988
MIR185 microRNA 185 0.227642
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.224884
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.223165
EP400 E1A binding protein p400 0.222136
PLVAP plasmalemma vesicle associated protein 0.221793
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.219057
TCHH trichohyalin 0.218374
IL7R interleukin 7 receptor 0.215992
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.215653
CIITA class II, major histocompatibility complex, transactivator 0.214297
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.213621
CHD4 chromodomain helicase DNA binding protein 4 0.212608
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.211261
SRPR signal recognition particle receptor (docking protein) 0.210589
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.209918
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 0.209248
CD44 CD44 molecule (Indian blood group) 0.208914
TXN thioredoxin 0.207912
MB myoglobin 0.205916
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.202618
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.20229
FOSL1 FOS-like antigen 1 0.200656
PTGES2 prostaglandin E synthase 2 0.198064
BIN3 bridging integrator 3 0.198064
CD1A CD1a molecule 0.191719
KRT20 keratin 20, type I 0.188938
KRT84 keratin 84, type II 0.187113
SGK1 serum/glucocorticoid regulated kinase 1 0.186811
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.184128
PIR pirin (iron-binding nuclear protein) 0.182957
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.182375
TGFB1 transforming growth factor, beta 1 0.182086
AVP arginine vasopressin 0.18151
GIPC1 GIPC PDZ domain containing family, member 1 0.17952
EPOR erythropoietin receptor 0.17896
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.178682
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.177029
NOTCH1 notch 1 0.176485
GCM2 glial cells missing homolog 2 (Drosophila) 0.176485
TLR4 toll-like receptor 4 0.174617
FOS FBJ murine osteosarcoma viral oncogene homolog 0.174354
FBXO32 F-box protein 32 0.174093
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.173314
CORT cortistatin 0.173314
INHBA inhibin, beta A 0.171535
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.170299
GPR17 G protein-coupled receptor 17 0.169091
RRAS related RAS viral (r-ras) oncogene homolog 0.168854
CD6 CD6 molecule 0.167915
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.167915
OPCML opioid binding protein/cell adhesion molecule-like 0.167915
ZBTB7A zinc finger and BTB domain containing 7A 0.167682
IL2RA interleukin 2 receptor, alpha 0.166995
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.165655
DPYD dihydropyrimidine dehydrogenase 0.165001
CREB1 cAMP responsive element binding protein 1 0.162908
SPRY2 sprouty homolog 2 (Drosophila) 0.162505
KARS lysyl-tRNA synthetase 0.162109
DSP desmoplakin 0.161716
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.161523
LAMP2 lysosomal-associated membrane protein 2 0.160387
TIMP2 TIMP metallopeptidase inhibitor 2 0.160387
SPN sialophorin 0.160203
PPARD peroxisome proliferator-activated receptor delta 0.158778
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1 0.140199
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.139354
CTNND1 catenin (cadherin-associated protein), delta 1 0.139161
IVL involucrin 0.137897
KRT14 keratin 14, type I 0.137354
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.13616
STS steroid sulfatase (microsomal), isozyme S 0.135478
PDPN podoplanin 0.134283
MAML2 mastermind-like 2 (Drosophila) 0.132544
KITLG KIT ligand 0.1316
ACOT13 acyl-CoA thioesterase 13 0.130367
S100A9 S100 calcium binding protein A9 0.129732
PCNA proliferating cell nuclear antigen 0.128622
TXNL1 thioredoxin-like 1 0.128424
FSCN3 fascin actin-bundling protein 3, testicular 0.124838
FSCN2 fascin actin-bundling protein 2, retinal 0.123856
VCAM1 vascular cell adhesion molecule 1 0.122644
ESR1 estrogen receptor 1 0.122377
FSCN1 fascin actin-bundling protein 1 0.119714
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.117338
PTHLH parathyroid hormone-like hormone 0.116524
NGFR nerve growth factor receptor 0.114923
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.114097
MMP7 matrix metallopeptidase 7 0.110771
PTH parathyroid hormone 0.106828
PGR progesterone receptor 0.103862
NGF nerve growth factor (beta polypeptide) 0.098235
NAPSA napsin A aspartic peptidase 0.097565
CDX2 caudal type homeobox 2 0.097292
BIRC5 baculoviral IAP repeat containing 5 0.089606
ESR2 estrogen receptor 2 (ER beta) 0.084254
CD68 CD68 molecule 0.083656