thymus cortex hypoplasia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description underdevelopment or reduced size, usually due to a reduced cell number, of the outer part of a thymus lobule that surrounds the medulla and is composed of closely packed lymphocytes (Mammalian Phenotype Ontology, MP_0000711)
External Link
Similar Terms
Downloads & Tools


20 gene mutations causing the thymus cortex hypoplasia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCC10 ATP-binding cassette, sub-family C (CFTR/MRP), member 10
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ARID5B AT rich interactive domain 5B (MRF1-like)
ASL argininosuccinate lyase
ATM ATM serine/threonine kinase
COMMD3-BMI1 COMMD3-BMI1 readthrough
CSF1 colony stimulating factor 1 (macrophage)
CUX1 cut-like homeobox 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2RG interleukin 2 receptor, gamma
JAK3 Janus kinase 3
LAMA2 laminin, alpha 2
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SGPL1 sphingosine-1-phosphate lyase 1
SOCS1 suppressor of cytokine signaling 1
T T, brachyury homolog (mouse)
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TREX1 three prime repair exonuclease 1
TTC7A tetratricopeptide repeat domain 7A