thyroiditis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description Updating to more specific UMLS_CUI from C0029495 to C0040147. (Human Disease Ontology, DOID_7166)
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Genes

243 genes co-occuring with the disease thyroiditis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TG thyroglobulin 3.33728
TPO thyroid peroxidase 2.76901
PRSS3 protease, serine, 3 2.32981
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 2.13466
TSHR thyroid stimulating hormone receptor 2.06036
TRH thyrotropin-releasing hormone 1.73368
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.65789
CD4 CD4 molecule 1.5115
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.4834
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 1.41095
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 1.26603
CALCA calcitonin-related polypeptide alpha 1.2582
FASLG Fas ligand (TNF superfamily, member 6) 1.23126
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.18109
CD79A CD79a molecule, immunoglobulin-associated alpha 1.16992
HLA-C major histocompatibility complex, class I, C 1.16179
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.10931
IFNA1 interferon, alpha 1 1.08621
POMC proopiomelanocortin 1.07236
FOXP3 forkhead box P3 1.07068
CXCL10 chemokine (C-X-C motif) ligand 10 1.04882
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 1.04504
PICALM phosphatidylinositol binding clathrin assembly protein 1.04377
IL2 interleukin 2 1.01723
RET ret proto-oncogene 0.991065
INS insulin 0.978426
GIF gastric intrinsic factor (vitamin B synthesis) 0.976744
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.947435
PTPRD protein tyrosine phosphatase, receptor type, D 0.939949
CASQ2 calsequestrin 2 (cardiac muscle) 0.931242
FLNB filamin B, beta 0.926279
HIST2H2AC histone cluster 2, H2ac 0.915139
HIST2H2AA3 histone cluster 2, H2aa3 0.914727
HIST2H2AA4 histone cluster 2, H2aa4 0.914727
CD40 CD40 molecule, TNF receptor superfamily member 5 0.912668
HLA-A major histocompatibility complex, class I, A 0.89582
ICAM1 intercellular adhesion molecule 1 0.887618
LGALS3 lectin, galactoside-binding, soluble, 3 0.863046
PRL prolactin 0.860999
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.849945
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.824128
IL1B interleukin 1, beta 0.798692
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.798692
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.783936
AIRE autoimmune regulator 0.763902
SLC26A4 solute carrier family 26 (anion exchanger), member 4 0.745985
IL2RA interleukin 2 receptor, alpha 0.745172
VIMP VCP-interacting membrane selenoprotein 0.741517
IL1A interleukin 1, alpha 0.737865
CXCL9 chemokine (C-X-C motif) ligand 9 0.724502
TNF tumor necrosis factor 0.720461
SLC30A10 solute carrier family 30, member 10 0.714005
CXCL11 chemokine (C-X-C motif) ligand 11 0.713601
IL6 interleukin 6 0.695905
THRB thyroid hormone receptor, beta 0.692296
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.691495
WEE2 WEE1 homolog 2 (S. pombe) 0.672324
HECA headcase homolog (Drosophila) 0.66199
CRP C-reactive protein, pentraxin-related 0.65288
OR6F1 olfactory receptor, family 6, subfamily F, member 1 0.644981
LNP1 leukemia NUP98 fusion partner 1 0.644981
PTH parathyroid hormone 0.643009
ZFAT zinc finger and AT hook domain containing 0.642221
SERINC5 serine incorporator 5 0.621792
CD5 CD5 molecule 0.611229
SDF4 stromal cell derived factor 4 0.596402
KRT19 keratin 19, type I 0.589779
HSPG2 heparan sulfate proteoglycan 2 0.58939
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.584719
PTCH1 patched 1 0.567997
CXCR3 chemokine (C-X-C motif) receptor 3 0.562558
TGFB1 transforming growth factor, beta 1 0.550134
ALB albumin 0.53928
MALT1 MALT1 paracaspase 0.533861
DBR1 debranching RNA lariats 1 0.524588
ALPPL2 alkaline phosphatase, placental-like 2 0.517265
ALPP alkaline phosphatase, placental 0.516879
ALPL alkaline phosphatase, liver/bone/kidney 0.516494
LTA lymphotoxin alpha 0.515725
IFNB1 interferon, beta 1, fibroblast 0.506123
IL4 interleukin 4 0.498849
TRAC T cell receptor alpha constant 0.494266
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.49274
C14ORF166 chromosome 14 open reading frame 166 0.487027
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.482844
DYNLT1 dynein, light chain, Tctex-type 1 0.476014
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.474498
B3GAT1 beta-1,3-glucuronyltransferase 1 0.474119
DUOXA2 dual oxidase maturation factor 2 0.467306
SLC36A2 solute carrier family 36 (proton/amino acid symporter), member 2 0.463527
IFNA21 interferon, alpha 21 0.461261
IL18 interleukin 18 0.455978
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.446935
IFNA17 interferon, alpha 17 0.439786
CD40LG CD40 ligand 0.437906
CD19 CD19 molecule 0.431144
GHRL ghrelin/obestatin prepropeptide 0.430017
ENO1 enolase 1, (alpha) 0.42139
IL10 interleukin 10 0.419517
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.418019
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.413527
GAST gastrin 0.412779
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.397843
FCRL3 Fc receptor-like 3 0.387794
BIRC3 baculoviral IAP repeat containing 3 0.387423
NCAM1 neural cell adhesion molecule 1 0.384451
CRH corticotropin releasing hormone 0.382594
CCL2 chemokine (C-C motif) ligand 2 0.381852
SP3 Sp3 transcription factor 0.380739
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.371847
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 0.366671
MXD3 MAX dimerization protein 3 0.361502
IFNA2 interferon, alpha 2 0.358551
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.357814
DUOXA1 dual oxidase maturation factor 1 0.357446
WDR11 WD repeat domain 11 0.352291
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.348614
MPO myeloperoxidase 0.344207
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 0.344207
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.342006
DIO1 deiodinase, iodothyronine, type I 0.339073
SST somatostatin 0.335778
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.334681
C4A complement component 4A (Rodgers blood group) 0.331025
TXNRD2 thioredoxin reductase 2 0.326646
TBX1 T-box 1 0.324458
CA1 carbonic anhydrase I 0.316092
LAD1 ladinin 1 0.312102
PLEK2 pleckstrin 2 0.30848
HIST1H2BE histone cluster 1, H2be 0.306672
HIST1H2BG histone cluster 1, H2bg 0.306672
HIST1H2BI histone cluster 1, H2bi 0.306672
LHX3 LIM homeobox 3 0.30631
OAT ornithine aminotransferase 0.305948
ABR active BCR-related 0.305226
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.300533
EARS2 glutamyl-tRNA synthetase 2, mitochondrial 0.297651
NELFCD negative elongation factor complex member C/D 0.296931
HSPA1L heat shock 70kDa protein 1-like 0.296211
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 0.289744
TSHB thyroid stimulating hormone, beta 0.289027
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.288668
PTPRC protein tyrosine phosphatase, receptor type, C 0.288668
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.285086
SELL selectin L 0.276514
EFTUD1 elongation factor Tu GTP binding domain containing 1 0.270819
CD68 CD68 molecule 0.266558
DCT dopachrome tautomerase 0.266203
TP53 tumor protein p53 0.265849
NAT9 N-acetyltransferase 9 (GCN5-related, putative) 0.261245
EBF3 early B-cell factor 3 0.253127
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.251366
NUMA1 nuclear mitotic apparatus protein 1 0.246799
IGF1 insulin-like growth factor 1 (somatomedin C) 0.246448
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.243295
MUC15 mucin 15, cell surface associated 0.242945
PRDX1 peroxiredoxin 1 0.241546
GC group-specific component (vitamin D binding protein) 0.238054
HRK harakiri, BCL2 interacting protein 0.237009
CLEC16A C-type lectin domain family 16, member A 0.23666
ZNF165 zinc finger protein 165 0.23353
HLX H2.0-like homeobox 0.232489
PDCD1 programmed cell death 1 0.232142
TXNDC9 thioredoxin domain containing 9 0.231102
VNN2 vanin 2 0.230409
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.224884
HLA-B major histocompatibility complex, class I, B 0.22454
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.22454
CD69 CD69 molecule 0.221793
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.221793
CYS1 cystin 1 0.220424
SMOC2 SPARC related modular calcium binding 2 0.219398
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.218034
CIAO1 cytosolic iron-sulfur assembly component 1 0.215992
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.213621
DUOX1 dual oxidase 1 0.211934
BCAS3 breast carcinoma amplified sequence 3 0.211261
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.210253
GPX3 glutathione peroxidase 3 0.209583
GPX4 glutathione peroxidase 4 0.206248
AFF2 AF4/FMR2 family, member 2 0.199681
BCL2 B-cell CLL/lymphoma 2 0.199033
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 0.19582
GLMN glomulin, FKBP associated protein 0.195501
IL12B interleukin 12B 0.195183
DUOX2 dual oxidase 2 0.194232
F3 coagulation factor III (thromboplastin, tissue factor) 0.192657
PNP purine nucleoside phosphorylase 0.192344
ICAM3 intercellular adhesion molecule 3 0.191408
NKX2-1 NK2 homeobox 1 0.190168
HBA2 hemoglobin, alpha 2 0.188326
LHCGR luteinizing hormone/choriogonadotropin receptor 0.187113
PSIP1 PC4 and SFRS1 interacting protein 1 0.18651
TRIO trio Rho guanine nucleotide exchange factor 0.185016
KALRN kalirin, RhoGEF kinase 0.185016
CXCR5 chemokine (C-X-C motif) receptor 5 0.180937
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.180652
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.176757
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.175947
C3 complement component 3 0.173571
TADA3 transcriptional adaptor 3 0.173571
LPO lactoperoxidase 0.170299
PRAMEF12 PRAME family member 12 0.168617
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.167682
THY1 Thy-1 cell surface antigen 0.167682
PRTN3 proteinase 3 0.165001
CPLX1 complexin 1 0.163523
CD276 CD276 molecule 0.163317
NCOA4 nuclear receptor coactivator 4 0.162109
IFIH1 interferon induced with helicase C domain 1 0.159838
PTEN phosphatase and tensin homolog 0.15948
LRP2 low density lipoprotein receptor-related protein 2 0.159124
TARP TCR gamma alternate reading frame protein 0.158605
LALBA lactalbumin, alpha- 0.142024
RER1 retention in endoplasmic reticulum sorting receptor 1 0.141949
PIP prolactin-induced protein 0.140649
CD226 CD226 molecule 0.138136
CHGA chromogranin A 0.133395
GRHL1 grainyhead-like 1 (Drosophila) 0.130787
ACOT7 acyl-CoA thioesterase 7 0.129746
ENO2 enolase 2 (gamma, neuronal) 0.127425
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.127131
SHBG sex hormone-binding globulin 0.12462
GHSR growth hormone secretagogue receptor 0.121941
PDGFB platelet-derived growth factor beta polypeptide 0.121001
SRL sarcalumenin 0.115127
NUCB2 nucleobindin 2 0.115007
GPX1 glutathione peroxidase 1 0.114767
LYPD1 LY6/PLAUR domain containing 1 0.114767
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.113607
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.113607
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.11253
ICAM2 intercellular adhesion molecule 2 0.112398
PAAF1 proteasomal ATPase-associated factor 1 0.111913
GPX7 glutathione peroxidase 7 0.111551
FLNA filamin A, alpha 0.11119
SRSF5 serine/arginine-rich splicing factor 5 0.110635
CD59 CD59 molecule, complement regulatory protein 0.110542
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1 0.10979
CD58 CD58 molecule 0.10979
GPX5 glutathione peroxidase 5 0.109742
CXCL13 chemokine (C-X-C motif) ligand 13 0.109646
PRSS50 protease, serine, 50 0.109598