tiabendazole-2840 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tiabendazole-2840 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACE2 angiotensin I converting enzyme 2
ADGRA2 adhesion G protein-coupled receptor A2
AGFG1 ArfGAP with FG repeats 1
ALCAM activated leukocyte cell adhesion molecule
ALDOB aldolase B, fructose-bisphosphate
AR androgen receptor
ARPIN actin-related protein 2/3 complex inhibitor
ATN1 atrophin 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAIAP2 BAI1-associated protein 2
C19ORF66 chromosome 19 open reading frame 66
CCNJL cyclin J-like
CD300C CD300c molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD82 CD82 molecule
CFLAR CASP8 and FADD-like apoptosis regulator
CIZ1 CDKN1A interacting zinc finger protein 1
CLMN calmin (calponin-like, transmembrane)
COL11A2 collagen, type XI, alpha 2
CUZD1 CUB and zona pellucida-like domains 1
DAPK2 death-associated protein kinase 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPY19L1P1 DPY19L1 pseudogene 1
DUSP10 dual specificity phosphatase 10
ERCC4 excision repair cross-complementation group 4
FAM63B family with sequence similarity 63, member B
FBXW12 F-box and WD repeat domain containing 12
FGF5 fibroblast growth factor 5
GNRHR gonadotropin-releasing hormone receptor
GTDC1 glycosyltransferase-like domain containing 1
GYG2 glycogenin 2
HFE hemochromatosis
HNRNPM heterogeneous nuclear ribonucleoprotein M
HPS1 Hermansky-Pudlak syndrome 1
IBSP integrin-binding sialoprotein
IDS iduronate 2-sulfatase
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KIAA0125 KIAA0125
KLRF1 killer cell lectin-like receptor subfamily F, member 1
LIMCH1 LIM and calponin homology domains 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MED18 mediator complex subunit 18
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MINK1 misshapen-like kinase 1
MKL1 megakaryoblastic leukemia (translocation) 1
MKRN3 makorin ring finger protein 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MNMIP1 manchette microtubule inner protein 1
MSL3 male-specific lethal 3 homolog (Drosophila)
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
PGR progesterone receptor
PICK1 protein interacting with PRKCA 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRDM2 PR domain containing 2, with ZNF domain
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTGIS prostaglandin I2 (prostacyclin) synthase
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RASA3 RAS p21 protein activator 3
RBMS2 RNA binding motif, single stranded interacting protein 2
RND2 Rho family GTPase 2
SFTPB surfactant protein B
SFXN3 sideroflexin 3
SH2D3A SH2 domain containing 3A
SH3BP2 SH3-domain binding protein 2
SIDT2 SID1 transmembrane family, member 2
SKI SKI proto-oncogene
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STXBP5L syntaxin binding protein 5-like
TBC1D30 TBC1 domain family, member 30
TCP10 t-complex 10
TFEB transcription factor EB
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLE2 transducin-like enhancer of split 2
TMEM63A transmembrane protein 63A
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
UCN urocortin
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZNF134 zinc finger protein 134
ZNF137P zinc finger protein 137, pseudogene
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMDHD2 amidohydrolase domain containing 2
ANKRD36 ankyrin repeat domain 36
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC6 armadillo repeat containing 6
ATAD5 ATPase family, AAA domain containing 5
B9D2 B9 protein domain 2
BAK1 BCL2-antagonist/killer 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C14ORF93 chromosome 14 open reading frame 93
CBX4 chromobox homolog 4
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CHPF chondroitin polymerizing factor
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTX4 deltex 4, E3 ubiquitin ligase
DUSP2 dual specificity phosphatase 2
ENO2 enolase 2 (gamma, neuronal)
ERCC5 excision repair cross-complementation group 5
F8 coagulation factor VIII, procoagulant component
FAM155B family with sequence similarity 155, member B
FAM198B family with sequence similarity 198, member B
FAM46C family with sequence similarity 46, member C
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
IGFBP6 insulin-like growth factor binding protein 6
IPO8 importin 8
IRAK4 interleukin-1 receptor-associated kinase 4
IRF1 interferon regulatory factor 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
KDM5C lysine (K)-specific demethylase 5C
KDM7A lysine (K)-specific demethylase 7A
LRP5 low density lipoprotein receptor-related protein 5
LRRC37A2 leucine rich repeat containing 37, member A2
LRRC8E leucine rich repeat containing 8 family, member E
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MB myoglobin
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MICALL2 MICAL-like 2
NDE1 nudE neurodevelopment protein 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OLFML3 olfactomedin-like 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PILRB paired immunoglobin-like type 2 receptor beta
PLA2G10 phospholipase A2, group X
PLA2G3 phospholipase A2, group III
POLL polymerase (DNA directed), lambda
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRKX protein kinase, X-linked
RAB3D RAB3D, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIPK4 receptor-interacting serine-threonine kinase 4
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RRAGB Ras-related GTP binding B
SALL2 spalt-like transcription factor 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNAI2 snail family zinc finger 2
SNHG3 small nucleolar RNA host gene 3
SPATA2L spermatogenesis associated 2-like
SSFA2 sperm specific antigen 2
STRN striatin, calmodulin binding protein
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYBU syntabulin (syntaxin-interacting)
TGIF1 TGFB-induced factor homeobox 1
THRAP3 thyroid hormone receptor associated protein 3
TNS2 tensin 2
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAIP TRAF interacting protein
TRIM66 tripartite motif containing 66
TTC33 tetratricopeptide repeat domain 33
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP6NL USP6 N-terminal like
YY2 YY2 transcription factor
ZNF204P zinc finger protein 204, pseudogene
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF428 zinc finger protein 428
ZNF571 zinc finger protein 571
ZNF665 zinc finger protein 665