tiabendazole-4579 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the tiabendazole-4579 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ADD2 adducin 2 (beta)
AKR1D1 aldo-keto reductase family 1, member D1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BMP2 bone morphogenetic protein 2
C19ORF26 chromosome 19 open reading frame 26
C22ORF24 chromosome 22 open reading frame 24
C5ORF42 chromosome 5 open reading frame 42
CACFD1 calcium channel flower domain containing 1
CADM4 cell adhesion molecule 4
CCP110 centriolar coiled coil protein 110kDa
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CNGA1 cyclic nucleotide gated channel alpha 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CREM cAMP responsive element modulator
CUZD1 CUB and zona pellucida-like domains 1
DOK4 docking protein 4
DPY19L1 dpy-19-like 1 (C. elegans)
DSCAM Down syndrome cell adhesion molecule
EGR2 early growth response 2
ENO3 enolase 3 (beta, muscle)
FBLN1 fibulin 1
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FLT4 fms-related tyrosine kinase 4
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRM8 glutamate receptor, metabotropic 8
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HEMK1 HemK methyltransferase family member 1
HHAT hedgehog acyltransferase
HOXA2 homeobox A2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IL1RN interleukin 1 receptor antagonist
INSR insulin receptor
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KIF1C kinesin family member 1C
KLK2 kallikrein-related peptidase 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LGALS8 lectin, galactoside-binding, soluble, 8
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MYO9B myosin IXB
MYOZ3 myozenin 3
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PARP11 poly (ADP-ribose) polymerase family, member 11
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G10 phospholipase A2, group X
PLIN2 perilipin 2
PRDM14 PR domain containing 14
PSG11 pregnancy specific beta-1-glycoprotein 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PVT1 Pvt1 oncogene (non-protein coding)
RAB3A RAB3A, member RAS oncogene family
RAG2 recombination activating gene 2
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
RPL13 ribosomal protein L13
RUNX1 runt-related transcription factor 1
SCAND2P SCAN domain containing 2 pseudogene
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC22A14 solute carrier family 22, member 14
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SPATA1 spermatogenesis associated 1
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTBN5 spectrin, beta, non-erythrocytic 5
STRN striatin, calmodulin binding protein
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBX2 T-box 2
TEF thyrotrophic embryonic factor
TK2 thymidine kinase 2, mitochondrial
TSFM Ts translation elongation factor, mitochondrial
WSB1 WD repeat and SOCS box containing 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF219 zinc finger protein 219
ZNF225 zinc finger protein 225
ZNF230 zinc finger protein 230
ZNF235 zinc finger protein 235
ZNF24 zinc finger protein 24
ZNF268 zinc finger protein 268

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACBD4 acyl-CoA binding domain containing 4
ADGRB2 adhesion G protein-coupled receptor B2
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD40 ankyrin repeat domain 40
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P1 annexin A2 pseudogene 1
AXIN1 axin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C19ORF40 chromosome 19 open reading frame 40
C21ORF91 chromosome 21 open reading frame 91
C22ORF46 chromosome 22 open reading frame 46
C4ORF29 chromosome 4 open reading frame 29
CA9 carbonic anhydrase IX
CINP cyclin-dependent kinase 2 interacting protein
CLEC2B C-type lectin domain family 2, member B
CLIC3 chloride intracellular channel 3
COL9A2 collagen, type IX, alpha 2
CPZ carboxypeptidase Z
CXCL3 chemokine (C-X-C motif) ligand 3
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DLL3 delta-like 3 (Drosophila)
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELSPBP1 epididymal sperm binding protein 1
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM184A family with sequence similarity 184, member A
FKBP10 FK506 binding protein 10, 65 kDa
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GALK1 galactokinase 1
GRAMD1C GRAM domain containing 1C
HIST1H1D histone cluster 1, H1d
HIST1H3G histone cluster 1, H3g
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IGSF3 immunoglobulin superfamily, member 3
IPO8 importin 8
ISL1 ISL LIM homeobox 1
ITPKA inositol-trisphosphate 3-kinase A
KDM5C lysine (K)-specific demethylase 5C
KLF13 Kruppel-like factor 13
LIME1 Lck interacting transmembrane adaptor 1
LMNB1 lamin B1
LMO7 LIM domain 7
LOC257152 uncharacterized LOC257152
MAMLD1 mastermind-like domain containing 1
MDFI MyoD family inhibitor
MLYCD malonyl-CoA decarboxylase
MOB3B MOB kinase activator 3B
MUC3B mucin 3B, cell surface associated
NACA2 nascent polypeptide-associated complex alpha subunit 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PRB3 proline-rich protein BstNI subfamily 3
PROX1 prospero homeobox 1
PRR15L proline rich 15-like
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTPRS protein tyrosine phosphatase, receptor type, S
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB5B RAB5B, member RAS oncogene family
RBL1 retinoblastoma-like 1
ROM1 retinal outer segment membrane protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A18 solute carrier family 22, member 18
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SNRPN small nuclear ribonucleoprotein polypeptide N
STK16 serine/threonine kinase 16
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TMEM212 transmembrane protein 212
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
UGT8 UDP glycosyltransferase 8
VASH1 vasohibin 1
ZDHHC24 zinc finger, DHHC-type containing 24
ZFHX3 zinc finger homeobox 3
ZNF214 zinc finger protein 214
ZNF334 zinc finger protein 334
ZNF426 zinc finger protein 426
ZNF862 zinc finger protein 862