tiapride-2292 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the tiapride-2292 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
ATF6B activating transcription factor 6 beta
BCL2L10 BCL2-like 10 (apoptosis facilitator)
C19ORF66 chromosome 19 open reading frame 66
C7ORF69 chromosome 7 open reading frame 69
CARTPT CART prepropeptide
CD53 CD53 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK19 cyclin-dependent kinase 19
CLCN7 chloride channel, voltage-sensitive 7
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL8A1 collagen, type VIII, alpha 1
COMT catechol-O-methyltransferase
CPQ carboxypeptidase Q
CRYGD crystallin, gamma D
CTSZ cathepsin Z
CXXC4 CXXC finger protein 4
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DMP1 dentin matrix acidic phosphoprotein 1
DOCK5 dedicator of cytokinesis 5
EN2 engrailed homeobox 2
ERCC2 excision repair cross-complementation group 2
FAM153A family with sequence similarity 153, member A
FAM155A family with sequence similarity 155, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FGFR1 fibroblast growth factor receptor 1
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS7 growth arrest-specific 7
GCGR glucagon receptor
GM2A GM2 ganglioside activator
GUCA2A guanylate cyclase activator 2A (guanylin)
H1F0 H1 histone family, member 0
HBEGF heparin-binding EGF-like growth factor
HNF1B HNF1 homeobox B
HOPX HOP homeobox
HOXB3 homeobox B3
HUS1 HUS1 checkpoint homolog (S. pombe)
INHBC inhibin, beta C
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KIAA0226L KIAA0226-like
KLK8 kallikrein-related peptidase 8
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMAN1 lectin, mannose-binding, 1
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MCPH1 microcephalin 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED31 mediator complex subunit 31
MTRF1L mitochondrial translational release factor 1-like
MX1 MX dynamin-like GTPase 1
NNAT neuronatin
NPM3 nucleophosmin/nucleoplasmin 3
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRN1 neuritin 1
OAZ3 ornithine decarboxylase antizyme 3
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PAMR1 peptidase domain containing associated with muscle regeneration 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PBX2 pre-B-cell leukemia homeobox 2
PCDHA5 protocadherin alpha 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHF1 PHD finger protein 1
PIGR polymeric immunoglobulin receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PML promyelocytic leukemia
POMT2 protein-O-mannosyltransferase 2
PRODH2 proline dehydrogenase (oxidase) 2
PSAT1 phosphoserine aminotransferase 1
PTCH1 patched 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RRBP1 ribosome binding protein 1
RTN2 reticulon 2
S100A8 S100 calcium binding protein A8
SAG S-antigen; retina and pineal gland (arrestin)
SH3BP2 SH3-domain binding protein 2
SLC35E2 solute carrier family 35, member E2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
STK17A serine/threonine kinase 17a
STK38 serine/threonine kinase 38
STMN3 stathmin-like 3
STS steroid sulfatase (microsomal), isozyme S
STXBP6 syntaxin binding protein 6 (amisyn)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D2 TBC1 domain family, member 2
TPK1 thiamin pyrophosphokinase 1
UCN urocortin
VIPR1 vasoactive intestinal peptide receptor 1
WIZ widely interspaced zinc finger motifs
ZC3H7B zinc finger CCCH-type containing 7B
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ADGRG2 adhesion G protein-coupled receptor G2
ARMC6 armadillo repeat containing 6
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BATF basic leucine zipper transcription factor, ATF-like
BMP4 bone morphogenetic protein 4
C4ORF29 chromosome 4 open reading frame 29
CA11 carbonic anhydrase XI
CA5BP1 carbonic anhydrase VB pseudogene 1
CAPN15 calpain 15
CAPN5 calpain 5
CCDC15 coiled-coil domain containing 15
CCDC186 coiled-coil domain containing 186
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD83 CD83 molecule
CGA glycoprotein hormones, alpha polypeptide
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAL4 dynein, axonemal, light chain 4
DNM1 dynamin 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELOVL4 ELOVL fatty acid elongase 4
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPPK1 epiplakin 1
FAM155B family with sequence similarity 155, member B
FBXW12 F-box and WD repeat domain containing 12
FOXI1 forkhead box I1
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLI3 GLI family zinc finger 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH2L G patch domain containing 2-like
GPHN gephyrin
GPR21 G protein-coupled receptor 21
GSTT1 glutathione S-transferase theta 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HP1BP3 heterochromatin protein 1, binding protein 3
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
KRI1 KRI1 homolog (S. cerevisiae)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LYPLA2P1 lysophospholipase II pseudogene 1
MED18 mediator complex subunit 18
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MON1B MON1 secretory trafficking family member B
PCDHB13 protocadherin beta 13
PHEX phosphate regulating endopeptidase homolog, X-linked
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PROCR protein C receptor, endothelial
PRPH peripherin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRS protein tyrosine phosphatase, receptor type, S
PTPRU protein tyrosine phosphatase, receptor type, U
RFTN1 raftlin, lipid raft linker 1
RFWD3 ring finger and WD repeat domain 3
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF170 ring finger protein 170
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCN1B sodium channel, voltage gated, type I beta subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC12A8 solute carrier family 12, member 8
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLMO1 slowmo homolog 1 (Drosophila)
SORBS3 sorbin and SH3 domain containing 3
SOWAHC sosondowah ankyrin repeat domain family member C
SPAG4 sperm associated antigen 4
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
ST5 suppression of tumorigenicity 5
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D17 TBC1 domain family, member 17
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
VASH2 vasohibin 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF365 zinc finger protein 365
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF747 zinc finger protein 747
ZNF91 zinc finger protein 91