tiapride-3663 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the tiapride-3663 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ADAM22 ADAM metallopeptidase domain 22
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADD2 adducin 2 (beta)
AGRN agrin
AIM2 absent in melanoma 2
AKAP5 A kinase (PRKA) anchor protein 5
ALOX12 arachidonate 12-lipoxygenase
AMN amnion associated transmembrane protein
ANXA10 annexin A10
APOA4 apolipoprotein A-IV
ARHGAP44 Rho GTPase activating protein 44
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
BTF3P11 basic transcription factor 3 pseudogene 11
C2ORF54 chromosome 2 open reading frame 54
C9ORF16 chromosome 9 open reading frame 16
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD226 CD226 molecule
CDH19 cadherin 19, type 2
CDRT1 CMT1A duplicated region transcript 1
CFP complement factor properdin
CHODL chondrolectin
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
CPA2 carboxypeptidase A2 (pancreatic)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCN decorin
DENND2D DENN/MADD domain containing 2D
DLC1 DLC1 Rho GTPase activating protein
DSCR4 Down syndrome critical region 4
DTNB dystrobrevin, beta
EFNB3 ephrin-B3
ESR1 estrogen receptor 1
FOXF1 forkhead box F1
FRMD1 FERM domain containing 1
FZD1 frizzled class receptor 1
GAB1 GRB2-associated binding protein 1
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GK glycerol kinase
GPR137 G protein-coupled receptor 137
HLA-DMB major histocompatibility complex, class II, DM beta
IGLJ3 immunoglobulin lambda joining 3
IL1RN interleukin 1 receptor antagonist
INADL InaD-like (Drosophila)
IRS4 insulin receptor substrate 4
ITPKA inositol-trisphosphate 3-kinase A
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LGALS4 lectin, galactoside-binding, soluble, 4
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK11 mitogen-activated protein kinase 11
MARK1 MAP/microtubule affinity-regulating kinase 1
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MEF2D myocyte enhancer factor 2D
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP24 matrix metallopeptidase 24 (membrane-inserted)
N4BP1 NEDD4 binding protein 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRIP3 nuclear receptor interacting protein 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI2 peptidyl arginine deiminase, type II
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLIN2 perilipin 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PTGDS prostaglandin D2 synthase 21kDa (brain)
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD51B RAD51 paralog B
RARB retinoic acid receptor, beta
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RGS17 regulator of G-protein signaling 17
RORB RAR-related orphan receptor B
RYR2 ryanodine receptor 2 (cardiac)
SALL1 spalt-like transcription factor 1
SCARF1 scavenger receptor class F, member 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERHL2 serine hydrolase-like 2
SLC25A30 solute carrier family 25, member 30
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLIT1 slit homolog 1 (Drosophila)
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
STK38 serine/threonine kinase 38
SYN3 synapsin III
TFDP3 transcription factor Dp family, member 3
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TP53 tumor protein p53
TTLL3 tubulin tyrosine ligase-like family member 3
TUBB1 tubulin, beta 1 class VI
USP29 ubiquitin specific peptidase 29
VGLL3 vestigial-like family member 3
ZFP64 ZFP64 zinc finger protein
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ALPK1 alpha-kinase 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOL6 apolipoprotein L, 6
ARC activity-regulated cytoskeleton-associated protein
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BTC betacellulin
C14ORF79 chromosome 14 open reading frame 79
C3 complement component 3
C8ORF44 chromosome 8 open reading frame 44
CCNT1 cyclin T1
CDKL3 cyclin-dependent kinase-like 3
CPED1 cadherin-like and PC-esterase domain containing 1
CPZ carboxypeptidase Z
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDA1 DET1 and DDB1 associated 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNAL4 dynein, axonemal, light chain 4
DPF3 D4, zinc and double PHD fingers, family 3
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
EXD3 exonuclease 3'-5' domain containing 3
FAM86C1 family with sequence similarity 86, member C1
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GBP2 guanylate binding protein 2, interferon-inducible
GJA8 gap junction protein, alpha 8, 50kDa
GPR176 G protein-coupled receptor 176
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1D histone cluster 1, H1d
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL17RB interleukin 17 receptor B
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KIRREL kin of IRRE like (Drosophila)
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
LMAN1 lectin, mannose-binding, 1
LMCD1 LIM and cysteine-rich domains 1
LYPD3 LY6/PLAUR domain containing 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MFSD6 major facilitator superfamily domain containing 6
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NUP62CL nucleoporin 62kDa C-terminal like
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PAX9 paired box 9
PC pyruvate carboxylase
PCOLCE procollagen C-endopeptidase enhancer
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PLA2G15 phospholipase A2, group XV
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNB3 plexin B3
POLM polymerase (DNA directed), mu
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTGES2 prostaglandin E synthase 2
PWAR5 Prader Willi/Angelman region RNA 5
RNF146 ring finger protein 146
SAYSD1 SAYSVFN motif domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRAL2 SIR2 antiphage like 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMO smoothened, frizzled class receptor
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
STAB2 stabilin 2
SYTL2 synaptotagmin-like 2
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TFCP2L1 transcription factor CP2-like 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM180 transmembrane protein 180
TMEM230 transmembrane protein 230
TMEM40 transmembrane protein 40
TMEM57 transmembrane protein 57
TMEM8A transmembrane protein 8A
TSPAN8 tetraspanin 8
ZNF253 zinc finger protein 253
ZNF510 zinc finger protein 510
ZNF665 zinc finger protein 665