| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the tiapride-4686 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1 | activin A receptor, type I |
| ADM | adrenomedullin |
| AGFG1 | ArfGAP with FG repeats 1 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| APC | adenomatous polyposis coli |
| AQP3 | aquaporin 3 (Gill blood group) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP1 | bone morphogenetic protein 1 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC121 | coiled-coil domain containing 121 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD47 | CD47 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEP76 | centrosomal protein 76kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CREM | cAMP responsive element modulator |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNB3 | ephrin-B3 |
| EZR | ezrin |
| FBXL5 | F-box and leucine-rich repeat protein 5 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLOT1 | flotillin 1 |
| GID4 | GID complex subunit 4 |
| GPATCH4 | G patch domain containing 4 |
| HIC2 | hypermethylated in cancer 2 |
| HOXB2 | homeobox B2 |
| IDUA | iduronidase, alpha-L- |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ITM2B | integral membrane protein 2B |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KIF25 | kinesin family member 25 |
| KLF12 | Kruppel-like factor 12 |
| KLHL20 | kelch-like family member 20 |
| LAMC2 | laminin, gamma 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LPIN2 | lipin 2 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLF1 | myeloid leukemia factor 1 |
| MR1 | major histocompatibility complex, class I-related |
| NDRG2 | NDRG family member 2 |
| NEK9 | NIMA-related kinase 9 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NME5 | NME/NM23 family member 5 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRL | neural retina leucine zipper |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PARVA | parvin, alpha |
| PCDHA6 | protocadherin alpha 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE8B | phosphodiesterase 8B |
| PER3 | period circadian clock 3 |
| PHF1 | PHD finger protein 1 |
| PLAC1 | placenta-specific 1 |
| POU4F1 | POU class 4 homeobox 1 |
| PRKCA | protein kinase C, alpha |
| PRKD3 | protein kinase D3 |
| PRND | prion protein 2 (dublet) |
| QSER1 | glutamine and serine rich 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RXRB | retinoid X receptor, beta |
| SAP30 | Sin3A-associated protein, 30kDa |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAPBP | TAP binding protein (tapasin) |
| TGFB2 | transforming growth factor, beta 2 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM242 | transmembrane protein 242 |
| TROVE2 | TROVE domain family, member 2 |
| UBE3A | ubiquitin protein ligase E3A |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VAMP4 | vesicle-associated membrane protein 4 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| YTHDC2 | YTH domain containing 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF226 | zinc finger protein 226 |
| ZNF304 | zinc finger protein 304 |
| ZNF362 | zinc finger protein 362 |
| ZNF41 | zinc finger protein 41 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| AHR | aryl hydrocarbon receptor |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BBC3 | BCL2 binding component 3 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSPN | claspin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CSF1R | colony stimulating factor 1 receptor |
| CUL9 | cullin 9 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DSPP | dentin sialophosphoprotein |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM131A | family with sequence similarity 131, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FGF23 | fibroblast growth factor 23 |
| FLT4 | fms-related tyrosine kinase 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLRA1 | glycine receptor, alpha 1 |
| GPC3 | glypican 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H2BO | histone cluster 1, H2bo |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXC8 | homeobox C8 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF1 | interferon regulatory factor 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KRT31 | keratin 31, type I |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC23 | leucine rich repeat containing 23 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NAG18 | NAG18 mRNA |
| NKX3-2 | NK3 homeobox 2 |
| PDE12 | phosphodiesterase 12 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PMEL | premelanosome protein |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RAB3D | RAB3D, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A9 | S100 calcium binding protein A9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SNTA1 | syntrophin, alpha 1 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIGD6 | tigger transposable element derived 6 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TRIM25 | tripartite motif containing 25 |
| TUBB2B | tubulin, beta 2B class IIb |
| UPK2 | uroplakin 2 |
| VASH2 | vasohibin 2 |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF134 | zinc finger protein 134 |
| ZNF652 | zinc finger protein 652 |