| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the tiapride-7362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AK5 | adenylate kinase 5 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BCL2 | B-cell CLL/lymphoma 2 |
| BGN | biglycan |
| BMP7 | bone morphogenetic protein 7 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CABIN1 | calcineurin binding protein 1 |
| CD33 | CD33 molecule |
| CD4 | CD4 molecule |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC42 | cell division cycle 42 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CES2 | carboxylesterase 2 |
| CHRDL1 | chordin-like 1 |
| CLDN18 | claudin 18 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COPE | coatomer protein complex, subunit epsilon |
| CPNE7 | copine VII |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CSN3 | casein kappa |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| DDN | dendrin |
| DFNB31 | deafness, autosomal recessive 31 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EDA | ectodysplasin A |
| EGR1 | early growth response 1 |
| EHF | ets homologous factor |
| EMX1 | empty spiracles homeobox 1 |
| FYB | FYN binding protein |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPSM3 | G-protein signaling modulator 3 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HIST1H4E | histone cluster 1, H4e |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HLF | hepatic leukemia factor |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IL17RA | interleukin 17 receptor A |
| IL6 | interleukin 6 |
| JAG1 | jagged 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFAP3 | microfibrillar-associated protein 3 |
| MPPE1 | metallophosphoesterase 1 |
| NAGLU | N-acetylglucosaminidase, alpha |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NKX3-2 | NK3 homeobox 2 |
| NPC1L1 | NPC1-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRF1 | nuclear respiratory factor 1 |
| NUDC | nudC nuclear distribution protein |
| OCA2 | oculocutaneous albinism II |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PHOX2A | paired-like homeobox 2a |
| PODNL1 | podocan-like 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRR4 | proline rich 4 (lacrimal) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB27B | RAB27B, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RANBP1 | RAN binding protein 1 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| REEP1 | receptor accessory protein 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RIN3 | Ras and Rab interactor 3 |
| ROM1 | retinal outer segment membrane protein 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERHL2 | serine hydrolase-like 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TRIM14 | tripartite motif containing 14 |
| UBQLN4 | ubiquilin 4 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| YIPF2 | Yip1 domain family, member 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF205 | zinc finger protein 205 |
| ZNF44 | zinc finger protein 44 |
| ZNF471 | zinc finger protein 471 |
| ZNF549 | zinc finger protein 549 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ACVR2B | activin A receptor, type IIB |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADAMTSL3 | ADAMTS-like 3 |
| AEN | apoptosis enhancing nuclease |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALS2CL | ALS2 C-terminal like |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BLOC1S1 | biogenesis of lysosomal organelles complex-1, subunit 1 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAPN15 | calpain 15 |
| CBX8 | chromobox homolog 8 |
| CCNE1 | cyclin E1 |
| CLEC16A | C-type lectin domain family 16, member A |
| CLEC2B | C-type lectin domain family 2, member B |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COQ6 | coenzyme Q6 monooxygenase |
| CUL9 | cullin 9 |
| CXORF56 | chromosome X open reading frame 56 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DIXDC1 | DIX domain containing 1 |
| DOCK1 | dedicator of cytokinesis 1 |
| EFNA4 | ephrin-A4 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPPK1 | epiplakin 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM50B | family with sequence similarity 50, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPALPP1 | GPALPP motifs containing 1 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 |
| HELZ | helicase with zinc finger |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IREB2 | iron-responsive element binding protein 2 |
| JAM3 | junctional adhesion molecule 3 |
| KIAA0513 | KIAA0513 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LHX6 | LIM homeobox 6 |
| MANEA | mannosidase, endo-alpha |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MEIS3P1 | Meis homeobox 3 pseudogene 1 |
| MITF | microphthalmia-associated transcription factor |
| MSRA | methionine sulfoxide reductase A |
| NABP2 | nucleic acid binding protein 2 |
| NINJ1 | ninjurin 1 |
| NLK | nemo-like kinase |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PEX13 | peroxisomal biogenesis factor 13 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| REEP4 | receptor accessory protein 4 |
| RIN1 | Ras and Rab interactor 1 |
| RNF170 | ring finger protein 170 |
| RNF25 | ring finger protein 25 |
| SETD6 | SET domain containing 6 |
| SIX1 | SIX homeobox 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SMIM8 | small integral membrane protein 8 |
| SP140L | SP140 nuclear body protein-like |
| STAC | SH3 and cysteine rich domain |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| USP6 | ubiquitin specific peptidase 6 |
| VASP | vasodilator-stimulated phosphoprotein |
| ZNF408 | zinc finger protein 408 |
| ZNF623 | zinc finger protein 623 |
| ZNF671 | zinc finger protein 671 |