tiaprofenic acid-2492 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the tiaprofenic acid-2492 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADCK4 aarF domain containing kinase 4
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOE apolipoprotein E
ATP13A2 ATPase type 13A2
BEGAIN brain-enriched guanylate kinase-associated
C1ORF95 chromosome 1 open reading frame 95
CCR4 chemokine (C-C motif) receptor 4
CD200 CD200 molecule
CD59 CD59 molecule, complement regulatory protein
CDK20 cyclin-dependent kinase 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP41 centrosomal protein 41kDa
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CPA4 carboxypeptidase A4
CREM cAMP responsive element modulator
CRMP1 collapsin response mediator protein 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTSF cathepsin F
CUL7 cullin 7
DEFA4 defensin, alpha 4, corticostatin
EDNRA endothelin receptor type A
EHD2 EH-domain containing 2
EML2 echinoderm microtubule associated protein like 2
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FN1 fibronectin 1
FOSL2 FOS-like antigen 2
FZD4 frizzled class receptor 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GOSR2 golgi SNAP receptor complex member 2
GPX2 glutathione peroxidase 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRTP1 growth hormone regulated TBC protein 1
HIC2 hypermethylated in cancer 2
INO80B INO80 complex subunit B
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT8 keratin 8, type II
LIME1 Lck interacting transmembrane adaptor 1
LOC390998 ribosomal protein L10 pseudogene
LTBP2 latent transforming growth factor beta binding protein 2
MAP4 microtubule-associated protein 4
METTL7A methyltransferase like 7A
MMP19 matrix metallopeptidase 19
MMP3 matrix metallopeptidase 3
MRPS12 mitochondrial ribosomal protein S12
MUC3A mucin 3A, cell surface associated
MYBPH myosin binding protein H
NID1 nidogen 1
NRP2 neuropilin 2
OLFML2A olfactomedin-like 2A
OSBPL10 oxysterol binding protein-like 10
PAIP2B poly(A) binding protein interacting protein 2B
PBX1 pre-B-cell leukemia homeobox 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCNX pecanex homolog (Drosophila)
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM7 PDZ and LIM domain 7 (enigma)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POMT2 protein-O-mannosyltransferase 2
POU5F1B POU class 5 homeobox 1B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PYCRL pyrroline-5-carboxylate reductase-like
RAB6B RAB6B, member RAS oncogene family
RANBP1 RAN binding protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RNF17 ring finger protein 17
RRBP1 ribosome binding protein 1
RTEL1 regulator of telomere elongation helicase 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SGSH N-sulfoglucosamine sulfohydrolase
SH3D21 SH3 domain containing 21
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLN sarcolipin
SPARCL1 SPARC-like 1 (hevin)
SPHK2 sphingosine kinase 2
SRSF7 serine/arginine-rich splicing factor 7
SSH3 slingshot protein phosphatase 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STX2 syntaxin 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAGLN3 transgelin 3
TDRD12 tudor domain containing 12
TECPR2 tectonin beta-propeller repeat containing 2
TEX13B testis expressed 13B
TSPAN4 tetraspanin 4
TTC38 tetratricopeptide repeat domain 38
ULBP2 UL16 binding protein 2
USP34 ubiquitin specific peptidase 34
YLPM1 YLP motif containing 1
YY1 YY1 transcription factor
ZFYVE9 zinc finger, FYVE domain containing 9
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRE1 adhesion G protein-coupled receptor E1
AEN apoptosis enhancing nuclease
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF70 chromosome 17 open reading frame 70
CA11 carbonic anhydrase XI
CAPN5 calpain 5
CCDC71 coiled-coil domain containing 71
CD300C CD300c molecule
CD70 CD70 molecule
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN2 chloride channel, voltage-sensitive 2
CLIP2 CAP-GLY domain containing linker protein 2
CNTN1 contactin 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CXCL2 chemokine (C-X-C motif) ligand 2
CXXC4 CXXC finger protein 4
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DNAH17 dynein, axonemal, heavy chain 17
DSPP dentin sialophosphoprotein
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
FAM131A family with sequence similarity 131, member A
FBP1 fructose-1,6-bisphosphatase 1
FKBPL FK506 binding protein like
FLT4 fms-related tyrosine kinase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAREM GRB2 associated, regulator of MAPK1
GATA6 GATA binding protein 6
GIPC1 GIPC PDZ domain containing family, member 1
HAMP hepcidin antimicrobial peptide
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
IFI6 interferon, alpha-inducible protein 6
IL3RA interleukin 3 receptor, alpha (low affinity)
JMJD4 jumonji domain containing 4
KDM8 lysine (K)-specific demethylase 8
KIF3B kinesin family member 3B
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP5L low density lipoprotein receptor-related protein 5-like
LTBP3 latent transforming growth factor beta binding protein 3
LTC4S leukotriene C4 synthase
MAP1S microtubule-associated protein 1S
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED22 mediator complex subunit 22
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRAS muscle RAS oncogene homolog
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDE1 nudE neurodevelopment protein 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NPFFR1 neuropeptide FF receptor 1
NT5M 5',3'-nucleotidase, mitochondrial
NUPR1 nuclear protein, transcriptional regulator, 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PDLIM2 PDZ and LIM domain 2 (mystique)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIPOX pipecolic acid oxidase
PITX2 paired-like homeodomain 2
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLCD1 phospholipase C, delta 1
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PQLC2 PQ loop repeat containing 2
PRDM1 PR domain containing 1, with ZNF domain
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSKH1 protein serine kinase H1
PTCD2 pentatricopeptide repeat domain 2
RAB33A RAB33A, member RAS oncogene family
REC8 REC8 meiotic recombination protein
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF126P1 ring finger protein 126 pseudogene 1
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SGCE sarcoglycan, epsilon
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNX29P2 sorting nexin 29 pseudogene 2
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
TBXAS1 thromboxane A synthase 1 (platelet)
THBS4 thrombospondin 4
TRIM25 tripartite motif containing 25
TSC22D4 TSC22 domain family, member 4
TSPAN5 tetraspanin 5
TTC30A tetratricopeptide repeat domain 30A
XAB2 XPA binding protein 2
YPEL1 yippee-like 1 (Drosophila)
ZNF219 zinc finger protein 219
ZNF23 zinc finger protein 23
ZNF345 zinc finger protein 345
ZNF580 zinc finger protein 580
ZNF668 zinc finger protein 668
ZNF768 zinc finger protein 768
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862