tiaprofenic acid-2852 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the tiaprofenic acid-2852 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
AGRN agrin
AKAP11 A kinase (PRKA) anchor protein 11
AKAP8L A kinase (PRKA) anchor protein 8-like
ANP32A-IT1 ANP32A intronic transcript 1
APLP2 amyloid beta (A4) precursor-like protein 2
ASB1 ankyrin repeat and SOCS box containing 1
ATM ATM serine/threonine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C4ORF29 chromosome 4 open reading frame 29
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CD82 CD82 molecule
CDC14B cell division cycle 14B
CDK13 cyclin-dependent kinase 13
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CFLAR CASP8 and FADD-like apoptosis regulator
DBT dihydrolipoamide branched chain transacylase E2
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EZR ezrin
FAM49B family with sequence similarity 49, member B
FAM63B family with sequence similarity 63, member B
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FKRP fukutin related protein
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GUSBP3 glucuronidase, beta pseudogene 3
HDAC6 histone deacetylase 6
HFE hemochromatosis
ICA1 islet cell autoantigen 1, 69kDa
IDS iduronate 2-sulfatase
IGF1R insulin-like growth factor 1 receptor
IL6ST interleukin 6 signal transducer
ING2 inhibitor of growth family, member 2
ITM2C integral membrane protein 2C
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD7 potassium channel tetramerization domain containing 7
KIAA1109 KIAA1109
KLHL24 kelch-like family member 24
LEPR leptin receptor
LRRC6 leucine rich repeat containing 6
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MBOAT7 membrane bound O-acyltransferase domain containing 7
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
MEX3D mex-3 RNA binding family member D
MITF microphthalmia-associated transcription factor
MYOF myoferlin
N4BP1 NEDD4 binding protein 1
NCKAP1 NCK-associated protein 1
NDRG2 NDRG family member 2
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFX1 nuclear transcription factor, X-box binding 1
NPC1 Niemann-Pick disease, type C1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAZ3 ornithine decarboxylase antizyme 3
PARD6B par-6 family cell polarity regulator beta
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
POM121 POM121 transmembrane nucleoporin
POU2F2 POU class 2 homeobox 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RABGAP1 RAB GTPase activating protein 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF39 ring finger protein 39
RNFT1 ring finger protein, transmembrane 1
RNGTT RNA guanylyltransferase and 5'-phosphatase
SATB2 SATB homeobox 2
SAYSD1 SAYSVFN motif domain containing 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCD5 stearoyl-CoA desaturase 5
SENP5 SUMO1/sentrin specific peptidase 5
SH3GL3 SH3-domain GRB2-like 3
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SRCAP Snf2-related CREBBP activator protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TM4SF1 transmembrane 4 L six family member 1
TMC6 transmembrane channel-like 6
TMEM53 transmembrane protein 53
TMEM63A transmembrane protein 63A
TRAK1 trafficking protein, kinesin binding 1
USP34 ubiquitin specific peptidase 34
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VEGFA vascular endothelial growth factor A
WAPAL wings apart-like homolog (Drosophila)
WDR76 WD repeat domain 76
WSB1 WD repeat and SOCS box containing 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZMYND8 zinc finger, MYND-type containing 8
ZNF451 zinc finger protein 451
ZNF609 zinc finger protein 609
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF770 zinc finger protein 770
ZW10 zw10 kinetochore protein
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACSL4 acyl-CoA synthetase long-chain family member 4
ADGRE5 adhesion G protein-coupled receptor E5
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANXA2P3 annexin A2 pseudogene 3
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ARC activity-regulated cytoskeleton-associated protein
ATP13A2 ATPase type 13A2
BAGE B melanoma antigen
BCL9 B-cell CLL/lymphoma 9
CA5BP1 carbonic anhydrase VB pseudogene 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLIP4 CAP-GLY domain containing linker protein family, member 4
CRLF1 cytokine receptor-like factor 1
CSTA cystatin A (stefin A)
CUEDC1 CUE domain containing 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DNM1 dynamin 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EDAR ectodysplasin A receptor
EHD4 EH-domain containing 4
F2R coagulation factor II (thrombin) receptor
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAM46C family with sequence similarity 46, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FOXA1 forkhead box A1
FRS2 fibroblast growth factor receptor substrate 2
FYCO1 FYVE and coiled-coil domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR27 G protein-coupled receptor 27
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT88 intraflagellar transport 88
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
ITPKC inositol-trisphosphate 3-kinase C
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIAA1107 KIAA1107
KLHL21 kelch-like family member 21
KLK5 kallikrein-related peptidase 5
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LPXN leupaxin
LRP5 low density lipoprotein receptor-related protein 5
METTL16 methyltransferase like 16
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRPL41 mitochondrial ribosomal protein L41
MUTYH mutY homolog
MVP major vault protein
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NOL12 nucleolar protein 12
PELI1 pellino E3 ubiquitin protein ligase 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
POPDC3 popeye domain containing 3
PPT2 palmitoyl-protein thioesterase 2
PRPH peripherin
PTDSS2 phosphatidylserine synthase 2
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIX1 SIX homeobox 1
SLC12A9 solute carrier family 12, member 9
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLMO2 slowmo homolog 2 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TH tyrosine hydroxylase
TMEM209 transmembrane protein 209
TRIM21 tripartite motif containing 21
TTBK2 tau tubulin kinase 2
TTC23 tetratricopeptide repeat domain 23
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
XAB2 XPA binding protein 2
YY2 YY2 transcription factor
ZFP37 ZFP37 zinc finger protein
ZNF205 zinc finger protein 205
ZNF551 zinc finger protein 551
ZNF606 zinc finger protein 606
ZNF639 zinc finger protein 639