| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the tiaprofenic acid-4091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY10 | adenylate cyclase 10 (soluble) |
| ADRA1A | adrenoceptor alpha 1A |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| APOB | apolipoprotein B |
| APOC4 | apolipoprotein C-IV |
| ATXN3L | ataxin 3-like |
| BEST1 | bestrophin 1 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BMP3 | bone morphogenetic protein 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C8A | complement component 8, alpha polypeptide |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CERS4 | ceramide synthase 4 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| COL14A1 | collagen, type XIV, alpha 1 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| ESR1 | estrogen receptor 1 |
| ETV3 | ets variant 3 |
| EXOSC1 | exosome component 1 |
| FGF18 | fibroblast growth factor 18 |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GAS7 | growth arrest-specific 7 |
| GIP | gastric inhibitory polypeptide |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| GYPC | glycophorin C (Gerbich blood group) |
| HFE | hemochromatosis |
| HOXD13 | homeobox D13 |
| HPR | haptoglobin-related protein |
| HSPB3 | heat shock 27kDa protein 3 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGB8 | integrin, beta 8 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLK2 | kallikrein-related peptidase 2 |
| KRTAP5-9 | keratin associated protein 5-9 |
| LEFTY2 | left-right determination factor 2 |
| LEP | leptin |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIMD2 | LIM domain containing 2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NMUR1 | neuromedin U receptor 1 |
| NOTCH4 | notch 4 |
| NOX4 | NADPH oxidase 4 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 |
| OMD | osteomodulin |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PDE12 | phosphodiesterase 12 |
| PHF3 | PHD finger protein 3 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRTN3 | proteinase 3 |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RET | ret proto-oncogene |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC45A2 | solute carrier family 45, member 2 |
| SPANXC | SPANX family, member C |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPRR2B | small proline-rich protein 2B |
| SRPK3 | SRSF protein kinase 3 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TACR1 | tachykinin receptor 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TPP1 | tripeptidyl peptidase I |
| TRGV5 | T cell receptor gamma variable 5 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| ZNF613 | zinc finger protein 613 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ADCY6 | adenylate cyclase 6 |
| AEN | apoptosis enhancing nuclease |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARSJ | arylsulfatase family, member J |
| AXIN1 | axin 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BICC1 | BicC family RNA binding protein 1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLDN15 | claudin 15 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYB5R2 | cytochrome b5 reductase 2 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAL4 | dynein, axonemal, light chain 4 |
| ECE1 | endothelin converting enzyme 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM118A | family with sequence similarity 118, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGF1 | fibroblast growth factor 1 (acidic) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| HDAC7 | histone deacetylase 7 |
| HIRA | histone cell cycle regulator |
| HOXA1 | homeobox A1 |
| HOXA6 | homeobox A6 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT140 | intraflagellar transport 140 |
| IPO8 | importin 8 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KIFC3 | kinesin family member C3 |
| KRT86 | keratin 86, type II |
| LAMA5 | laminin, alpha 5 |
| LMNB1 | lamin B1 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MAGEF1 | melanoma antigen family F1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MON1B | MON1 secretory trafficking family member B |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NOL12 | nucleolar protein 12 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RECQL4 | RecQ protein-like 4 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNDC3B | RUN domain containing 3B |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SETDB1 | SET domain, bifurcated 1 |
| SIX1 | SIX homeobox 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNIP1 | Smad nuclear interacting protein 1 |
| SSTR4 | somatostatin receptor 4 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TENM4 | teneurin transmembrane protein 4 |
| TMEM209 | transmembrane protein 209 |
| TMSB15A | thymosin beta 15a |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPAN2 | tetraspanin 2 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR4 | WD repeat domain 4 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF10 | zinc finger protein 10 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF280D | zinc finger protein 280D |
| ZNF34 | zinc finger protein 34 |
| ZNF408 | zinc finger protein 408 |
| ZNF76 | zinc finger protein 76 |
