tiaprofenic acid-4171 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the tiaprofenic acid-4171 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACAN aggrecan
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAM8 ADAM metallopeptidase domain 8
ADGRG1 adhesion G protein-coupled receptor G1
ALPK1 alpha-kinase 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
BAIAP3 BAI1-associated protein 3
BMP8A bone morphogenetic protein 8a
C10ORF95 chromosome 10 open reading frame 95
C14ORF1 chromosome 14 open reading frame 1
C3ORF18 chromosome 3 open reading frame 18
C5ORF42 chromosome 5 open reading frame 42
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN10 calpain 10
CASP4 caspase 4, apoptosis-related cysteine peptidase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFAP69 cilia and flagella associated protein 69
CFDP1 craniofacial development protein 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CNTNAP2 contactin associated protein-like 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL6A3 collagen, type VI, alpha 3
CST4 cystatin S
CTIF CBP80/20-dependent translation initiation factor
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAO D-amino-acid oxidase
DAPK1 death-associated protein kinase 1
DENND3 DENN/MADD domain containing 3
DNAI2 dynein, axonemal, intermediate chain 2
DOCK6 dedicator of cytokinesis 6
EDN1 endothelin 1
ELL2 elongation factor, RNA polymerase II, 2
EMID1 EMI domain containing 1
F5 coagulation factor V (proaccelerin, labile factor)
FABP3 fatty acid binding protein 3, muscle and heart
FGF6 fibroblast growth factor 6
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GBP1 guanylate binding protein 1, interferon-inducible
GIPC2 GIPC PDZ domain containing family, member 2
GSK3A glycogen synthase kinase 3 alpha
GTPBP1 GTP binding protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HBE1 hemoglobin, epsilon 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL1RL1 interleukin 1 receptor-like 1
INA internexin neuronal intermediate filament protein, alpha
ING1 inhibitor of growth family, member 1
INO80B INO80 complex subunit B
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIF1C kinesin family member 1C
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRRC37A3 leucine rich repeat containing 37, member A3
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAPK11 mitogen-activated protein kinase 11
MAPK7 mitogen-activated protein kinase 7
MBD2 methyl-CpG binding domain protein 2
MPPE1 metallophosphoesterase 1
MUC8 mucin 8
NCKIPSD NCK interacting protein with SH3 domain
NKX2-5 NK2 homeobox 5
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOX1 NADPH oxidase 1
OSBPL10 oxysterol binding protein-like 10
PARVB parvin, beta
PCDHB1 protocadherin beta 1
PDAP1 PDGFA associated protein 1
PDE10A phosphodiesterase 10A
PEG10 paternally expressed 10
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PKNOX2 PBX/knotted 1 homeobox 2
PML promyelocytic leukemia
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDM9 PR domain containing 9
PTPRB protein tyrosine phosphatase, receptor type, B
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SSX3 synovial sarcoma, X breakpoint 3
STS steroid sulfatase (microsomal), isozyme S
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNMD tenomodulin
TRIM49 tripartite motif containing 49
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UBQLN4 ubiquilin 4
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator
ZNF646 zinc finger protein 646
ZNF682 zinc finger protein 682

decreased expression

Symbol Name
ADGRE1 adhesion G protein-coupled receptor E1
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ATG10 autophagy related 10
B9D2 B9 protein domain 2
BCAS1 breast carcinoma amplified sequence 1
BIRC7 baculoviral IAP repeat containing 7
C17ORF53 chromosome 17 open reading frame 53
C5 complement component 5
CAMK1D calcium/calmodulin-dependent protein kinase ID
CCDC25 coiled-coil domain containing 25
CCDC71 coiled-coil domain containing 71
CDKL3 cyclin-dependent kinase-like 3
CES3 carboxylesterase 3
CFHR4 complement factor H-related 4
CGA glycoprotein hormones, alpha polypeptide
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CPB2 carboxypeptidase B2 (plasma)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DCBLD2 discoidin, CUB and LCCL domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNASE1L3 deoxyribonuclease I-like 3
DSPP dentin sialophosphoprotein
DUSP13 dual specificity phosphatase 13
ENO3 enolase 3 (beta, muscle)
ERCC2 excision repair cross-complementation group 2
FBXO2 F-box protein 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAS2 growth arrest-specific 2
GK3P glycerol kinase 3 pseudogene
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRM6 glutamate receptor, metabotropic 6
GSTP1 glutathione S-transferase pi 1
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HOOK1 hook microtubule-tethering protein 1
IL18 interleukin 18
INHA inhibin, alpha
ITFG2 integrin alpha FG-GAP repeat containing 2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT75 keratin 75, type II
KRT83 keratin 83, type II
LEFTY2 left-right determination factor 2
LENEP lens epithelial protein
LMTK2 lemur tyrosine kinase 2
MAGEA3 melanoma antigen family A3
MAPK10 mitogen-activated protein kinase 10
MTMR6 myotubularin related protein 6
MUC3A mucin 3A, cell surface associated
MX2 MX dynamin-like GTPase 2
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUPR1 nuclear protein, transcriptional regulator, 1
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PARG poly (ADP-ribose) glycohydrolase
PEX26 peroxisomal biogenesis factor 26
PIPOX pipecolic acid oxidase
PLAC4 placenta-specific 4
PQLC2 PQ loop repeat containing 2
PTK6 protein tyrosine kinase 6
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGS19 regulator of G-protein signaling 19
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RPS4Y1 ribosomal protein S4, Y-linked 1
SAMD9 sterile alpha motif domain containing 9
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLMO1 slowmo homolog 1 (Drosophila)
SNCAIP synuclein, alpha interacting protein
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAS2R4 taste receptor, type 2, member 4
TBC1D2 TBC1 domain family, member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLR2 toll-like receptor 2
TOR4A torsin family 4, member A
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UCN urocortin
UNC119 unc-119 homolog (C. elegans)
VPREB3 pre-B lymphocyte 3
WNT16 wingless-type MMTV integration site family, member 16
ZNF205 zinc finger protein 205
ZNF230 zinc finger protein 230
ZNF76 zinc finger protein 76