ticam1 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	toll-like receptor adaptor molecule 1\|This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 148022)
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Genes

13 genes co-occuring with the biological term ticam1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AZI2	5-azacytidine induced 2
IFNB1	interferon, beta 1, fibroblast
IRF3	interferon regulatory factor 3
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PVR	poliovirus receptor
RALBP1	ralA binding protein 1
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1
TICAM1	toll-like receptor adaptor molecule 1
TICAM2	toll-like receptor adaptor molecule 2
TLR3	toll-like receptor 3
TLR4	toll-like receptor 4
TRAF2	TNF receptor-associated factor 2
TRAF6	TNF receptor-associated factor 6, E3 ubiquitin protein ligase