ticarcillin-5829 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the ticarcillin-5829 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARHGAP44 Rho GTPase activating protein 44
BAAT bile acid CoA:amino acid N-acyltransferase
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
BMP2 bone morphogenetic protein 2
BRWD1 bromodomain and WD repeat domain containing 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C5ORF45 chromosome 5 open reading frame 45
CCDC22 coiled-coil domain containing 22
CDC14B cell division cycle 14B
CFLAR CASP8 and FADD-like apoptosis regulator
CHEK2 checkpoint kinase 2
CLCN7 chloride channel, voltage-sensitive 7
CNGB3 cyclic nucleotide gated channel beta 3
CNR2 cannabinoid receptor 2 (macrophage)
COL5A1 collagen, type V, alpha 1
COL9A3 collagen, type IX, alpha 3
CRTC1 CREB regulated transcription coactivator 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DCT dopachrome tautomerase
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOHH deoxyhypusine hydroxylase/monooxygenase
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
E2F4 E2F transcription factor 4, p107/p130-binding
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ESR1 estrogen receptor 1
EVC Ellis van Creveld protein
FAM184A family with sequence similarity 184, member A
FAT4 FAT atypical cadherin 4
FBXL7 F-box and leucine-rich repeat protein 7
FCMR Fc fragment of IgM receptor
FH fumarate hydratase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRK6 G protein-coupled receptor kinase 6
GSTM5 glutathione S-transferase mu 5
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H2AI histone cluster 1, H2ai
HOXA11 homeobox A11
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSF2BP heat shock transcription factor 2 binding protein
IFI6 interferon, alpha-inducible protein 6
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL1RN interleukin 1 receptor antagonist
ITGB4 integrin, beta 4
LAMC2 laminin, gamma 2
LAT2 linker for activation of T cells family, member 2
LDB3 LIM domain binding 3
LOC729164 hCG1732469
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP6 low density lipoprotein receptor-related protein 6
MANBA mannosidase, beta A, lysosomal
MAST2 microtubule associated serine/threonine kinase 2
MST1L macrophage stimulating 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYRF myelin regulatory factor
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOL10 nucleolar protein 10
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OSBPL2 oxysterol binding protein-like 2
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAX5 paired box 5
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP5C protein phosphatase 5, catalytic subunit
PURA purine-rich element binding protein A
PXN paxillin
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RARG retinoic acid receptor, gamma
RPL7 ribosomal protein L7
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SIX3 SIX homeobox 3
SKIL SKI-like proto-oncogene
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC43A3 solute carrier family 43, member 3
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SORBS1 sorbin and SH3 domain containing 1
TEX40 testis expressed 40
TGOLN2 trans-golgi network protein 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM140 transmembrane protein 140
TNC tenascin C
TSKU tsukushi, small leucine rich proteoglycan
TTC38 tetratricopeptide repeat domain 38
TUBGCP5 tubulin, gamma complex associated protein 5
TULP4 tubby like protein 4
VAC14 Vac14 homolog (S. cerevisiae)
WIPF1 WAS/WASL interacting protein family, member 1
ZBTB43 zinc finger and BTB domain containing 43
ZNF639 zinc finger protein 639
ZNF688 zinc finger protein 688
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
AFAP1 actin filament associated protein 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD36 ankyrin repeat domain 36
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP10D ATPase, class V, type 10D
ATP13A2 ATPase type 13A2
BAG4 BCL2-associated athanogene 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BDNF brain-derived neurotrophic factor
C1ORF115 chromosome 1 open reading frame 115
C1ORF159 chromosome 1 open reading frame 159
C1ORF56 chromosome 1 open reading frame 56
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CCDC130 coiled-coil domain containing 130
CCNT1 cyclin T1
CD3EAP CD3e molecule, epsilon associated protein
CDADC1 cytidine and dCMP deaminase domain containing 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CINP cyclin-dependent kinase 2 interacting protein
CLCF1 cardiotrophin-like cytokine factor 1
CLCN5 chloride channel, voltage-sensitive 5
CPEB1 cytoplasmic polyadenylation element binding protein 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DNAL4 dynein, axonemal, light chain 4
DUSP8 dual specificity phosphatase 8
E4F1 E4F transcription factor 1
ELOVL4 ELOVL fatty acid elongase 4
FABP4 fatty acid binding protein 4, adipocyte
FAM102A family with sequence similarity 102, member A
FAM222B family with sequence similarity 222, member B
FURIN furin (paired basic amino acid cleaving enzyme)
GAMT guanidinoacetate N-methyltransferase
GCA grancalcin, EF-hand calcium binding protein
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HIST1H2AM histone cluster 1, H2am
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLX H2.0-like homeobox
HMG20A high mobility group 20A
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IFT52 intraflagellar transport 52
IFT81 intraflagellar transport 81
IL17RB interleukin 17 receptor B
KCTD7 potassium channel tetramerization domain containing 7
KIF20B kinesin family member 20B
KLC2 kinesin light chain 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL3 kelch-like family member 3
LINC00339 long intergenic non-protein coding RNA 339
LRRK1 leucine-rich repeat kinase 1
MED9 mediator complex subunit 9
MEIS1 Meis homeobox 1
MPI mannose phosphate isomerase
NARFL nuclear prelamin A recognition factor-like
NOTCH1 notch 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PAQR6 progestin and adipoQ receptor family member VI
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PDE12 phosphodiesterase 12
PDZD2 PDZ domain containing 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
RPS17P5 ribosomal protein S17 pseudogene 5
SAMD9 sterile alpha motif domain containing 9
SECISBP2 SECIS binding protein 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SPAG4 sperm associated antigen 4
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STEAP4 STEAP family member 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TKFC triokinase/FMN cyclase
TMEM212 transmembrane protein 212
TMEM57 transmembrane protein 57
TMEM62 transmembrane protein 62
TMEM8B transmembrane protein 8B
TNNI3 troponin I type 3 (cardiac)
TNS2 tensin 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBFD1 ubiquitin family domain containing 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR91 WD repeat domain 91
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC24 zinc finger, DHHC-type containing 24