ticlopidine-1475 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the ticlopidine-1475 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
APOC1 apolipoprotein C-I
AREG amphiregulin
ATF3 activating transcription factor 3
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BHLHE40 basic helix-loop-helix family, member e40
C14ORF79 chromosome 14 open reading frame 79
C3 complement component 3
C5AR2 complement component 5a receptor 2
C8ORF60 chromosome 8 open reading frame 60
CCL5 chemokine (C-C motif) ligand 5
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COL2A1 collagen, type II, alpha 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLX2 distal-less homeobox 2
DNM3 dynamin 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM169A family with sequence similarity 169, member A
FGF2 fibroblast growth factor 2 (basic)
FOXG1 forkhead box G1
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMPR guanosine monophosphate reductase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR176 G protein-coupled receptor 176
HBEGF heparin-binding EGF-like growth factor
HCFC1 host cell factor C1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2BJ histone cluster 1, H2bj
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC10 homeobox C10
ICAM1 intercellular adhesion molecule 1
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF4 Kruppel-like factor 4 (gut)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP6 low density lipoprotein receptor-related protein 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBD1 methyl-CpG binding domain protein 1
MBD2 methyl-CpG binding domain protein 2
MYRIP myosin VIIA and Rab interacting protein
NAV2 neuron navigator 2
NFIL3 nuclear factor, interleukin 3 regulated
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OASL 2'-5'-oligoadenylate synthetase-like
PDCD6 programmed cell death 6
PER1 period circadian clock 1
PGR progesterone receptor
PHF14 PHD finger protein 14
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLCD1 phospholipase C, delta 1
PLTP phospholipid transfer protein
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PODNL1 podocan-like 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF170 ring finger protein 170
RUNX1 runt-related transcription factor 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPHK2 sphingosine kinase 2
SRCAP Snf2-related CREBBP activator protein
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK17B serine/threonine kinase 17b
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TES testin LIM domain protein
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB3 tribbles pseudokinase 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UNC93B1 unc-93 homolog B1 (C. elegans)
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP4 Rho GTPase activating protein 4
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARL15 ADP-ribosylation factor-like 15
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BPGM 2,3-bisphosphoglycerate mutase
C17ORF80 chromosome 17 open reading frame 80
C19ORF40 chromosome 19 open reading frame 40
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CAPN5 calpain 5
CGREF1 cell growth regulator with EF-hand domain 1
CLCN6 chloride channel, voltage-sensitive 6
CNGB3 cyclic nucleotide gated channel beta 3
CST6 cystatin E/M
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF5A2 eukaryotic translation initiation factor 5A2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM86C1 family with sequence similarity 86, member C1
FBXL15 F-box and leucine-rich repeat protein 15
FBXL2 F-box and leucine-rich repeat protein 2
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRTP1 growth hormone regulated TBC protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL22 interleukin 22
ITPKB inositol-trisphosphate 3-kinase B
KLK5 kallikrein-related peptidase 5
LIN7A lin-7 homolog A (C. elegans)
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
MAP6D1 MAP6 domain containing 1
METTL16 methyltransferase like 16
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
PCDHA9 protocadherin alpha 9
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLA2G3 phospholipase A2, group III
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PODXL2 podocalyxin-like 2
POLH polymerase (DNA directed), eta
PQLC1 PQ loop repeat containing 1
PRKCE protein kinase C, epsilon
PRR14L proline rich 14-like
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB8B RAB8B, member RAS oncogene family
RECQL4 RecQ protein-like 4
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
SHARPIN SHANK-associated RH domain interactor
SIL1 SIL1 nucleotide exchange factor
SIRT6 sirtuin 6
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
SYCP2 synaptonemal complex protein 2
TCTN2 tectonic family member 2
TLN1 talin 1
TMEM180 transmembrane protein 180
TNK1 tyrosine kinase, non-receptor, 1
TRIM5 tripartite motif containing 5
UBQLN4 ubiquilin 4
VEGFC vascular endothelial growth factor C
VIPR1 vasoactive intestinal peptide receptor 1
WLS wntless Wnt ligand secretion mediator
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF254 zinc finger protein 254
ZNF34 zinc finger protein 34
ZNF423 zinc finger protein 423
ZNF552 zinc finger protein 552
ZNF770 zinc finger protein 770