ticlopidine-1975 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the ticlopidine-1975 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABT1 activator of basal transcription 1
ACACA acetyl-CoA carboxylase alpha
ACTN4 actinin, alpha 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
APOC4 apolipoprotein C-IV
ARFIP1 ADP-ribosylation factor interacting protein 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BMPR1A bone morphogenetic protein receptor, type IA
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BPI bactericidal/permeability-increasing protein
CD82 CD82 molecule
CDC37 cell division cycle 37
CDK12 cyclin-dependent kinase 12
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHD1L chromodomain helicase DNA binding protein 1-like
CIZ1 CDKN1A interacting zinc finger protein 1
CKB creatine kinase, brain
CLCN6 chloride channel, voltage-sensitive 6
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CS citrate synthase
CTNS cystinosin, lysosomal cystine transporter
DBF4 DBF4 zinc finger
DGKD diacylglycerol kinase, delta 130kDa
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DRG2 developmentally regulated GTP binding protein 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EGLN1 egl-9 family hypoxia-inducible factor 1
ELMO2 engulfment and cell motility 2
FKTN fukutin
FPGT fucose-1-phosphate guanylyltransferase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HRH1 histamine receptor H1
HSPA4L heat shock 70kDa protein 4-like
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JRKL JRK-like
KRIT1 KRIT1, ankyrin repeat containing
LBP lipopolysaccharide binding protein
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
METRN meteorin, glial cell differentiation regulator
MGAM maltase-glucoamylase
MON2 MON2 homolog (S. cerevisiae)
MRPL19 mitochondrial ribosomal protein L19
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUTYH mutY homolog
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL10 myosin, light chain 10, regulatory
NAAA N-acylethanolamine acid amidase
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NDRG3 NDRG family member 3
NEK7 NIMA-related kinase 7
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OGFRL1 opioid growth factor receptor-like 1
OMG oligodendrocyte myelin glycoprotein
PAOX polyamine oxidase (exo-N4-amino)
PAQR3 progestin and adipoQ receptor family member III
PARG poly (ADP-ribose) glycohydrolase
PLA2G5 phospholipase A2, group V
PLS1 plastin 1
PODNL1 podocan-like 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPAP2A phosphatidic acid phosphatase type 2A
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma
PRPF39 pre-mRNA processing factor 39
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAP1GAP RAP1 GTPase activating protein
RGS1 regulator of G-protein signaling 1
RNASE3 ribonuclease, RNase A family, 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPL35A ribosomal protein L35a
SETD4 SET domain containing 4
SIRT1 sirtuin 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC38A7 solute carrier family 38, member 7
STBD1 starch binding domain 1
STK19 serine/threonine kinase 19
STK39 serine threonine kinase 39
STRN3 striatin, calmodulin binding protein 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TJP2 tight junction protein 2
TM2D1 TM2 domain containing 1
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM41B transmembrane protein 41B
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBGCP3 tubulin, gamma complex associated protein 3
USF2 upstream transcription factor 2, c-fos interacting
ZNF250 zinc finger protein 250
ZNF473 zinc finger protein 473
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACO1 aconitase 1, soluble
ACP2 acid phosphatase 2, lysosomal
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADIPOR2 adiponectin receptor 2
ADORA2B adenosine A2b receptor
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APH1B APH1B gamma secretase subunit
ASB13 ankyrin repeat and SOCS box containing 13
AURKB aurora kinase B
BATF3 basic leucine zipper transcription factor, ATF-like 3
C6ORF47 chromosome 6 open reading frame 47
C9ORF114 chromosome 9 open reading frame 114
CAMTA2 calmodulin binding transcription activator 2
CCDC130 coiled-coil domain containing 130
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLDN15 claudin 15
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CSNK1G3 casein kinase 1, gamma 3
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DOK3 docking protein 3
DPF2 D4, zinc and double PHD fingers family 2
DPH2 DPH2 homolog (S. cerevisiae)
F13A1 coagulation factor XIII, A1 polypeptide
FAM193B family with sequence similarity 193, member B
FPGS folylpolyglutamate synthase
GALNS galactosamine (N-acetyl)-6-sulfatase
GCC1 GRIP and coiled-coil domain containing 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJD2 gap junction protein, delta 2, 36kDa
GMEB1 glucocorticoid modulatory element binding protein 1
GMPPB GDP-mannose pyrophosphorylase B
GTF2IRD1 GTF2I repeat domain containing 1
GYS1 glycogen synthase 1 (muscle)
HIST1H1E histone cluster 1, H1e
IFI30 interferon, gamma-inducible protein 30
IGBP1 immunoglobulin (CD79A) binding protein 1
ITFG1 integrin alpha FG-GAP repeat containing 1
ITGA10 integrin, alpha 10
KCTD15 potassium channel tetramerization domain containing 15
KIAA0753 KIAA0753
KLHL12 kelch-like family member 12
LAMP5 lysosomal-associated membrane protein family, member 5
LIMD2 LIM domain containing 2
LOC642236 FSHD region gene 1 pseudogene
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPPR3 lipid phosphate phosphatase-related protein type 3
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
LUC7L LUC7-like (S. cerevisiae)
MARCKSL1 MARCKS-like 1
MITF microphthalmia-associated transcription factor
MTMR14 myotubularin related protein 14
NEK11 NIMA-related kinase 11
NOL6 nucleolar protein 6 (RNA-associated)
ORAI3 ORAI calcium release-activated calcium modulator 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK1IP1 PAK1 interacting protein 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNPO pyridoxamine 5'-phosphate oxidase
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP6R3 protein phosphatase 6, regulatory subunit 3
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB20 RAB20, member RAS oncogene family
RBBP5 retinoblastoma binding protein 5
RBM47 RNA binding motif protein 47
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SATB1 SATB homeobox 1
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEPW1 selenoprotein W, 1
SF3B2 splicing factor 3b, subunit 2, 145kDa
SIRAL2 SIR2 antiphage like 2
SIRT6 sirtuin 6
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLPI secretory leukocyte peptidase inhibitor
SMYD5 SMYD family member 5
SP140L SP140 nuclear body protein-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
TESK1 testis-specific kinase 1
TMED1 transmembrane emp24 protein transport domain containing 1
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TSSC4 tumor suppressing subtransferable candidate 4
WNT10B wingless-type MMTV integration site family, member 10B
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBED1 zinc finger, BED-type containing 1
ZC3H12A zinc finger CCCH-type containing 12A
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF282 zinc finger protein 282