ticlopidine-4155 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the ticlopidine-4155 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABI2 abl-interactor 2
ACPP acid phosphatase, prostate
ADGRF5 adhesion G protein-coupled receptor F5
ADGRG1 adhesion G protein-coupled receptor G1
AKAP7 A kinase (PRKA) anchor protein 7
AKR1C1 aldo-keto reductase family 1, member C1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ATF3 activating transcription factor 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL2 B-cell CLL/lymphoma 2
BIRC3 baculoviral IAP repeat containing 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C10ORF12 chromosome 10 open reading frame 12
C2ORF72 chromosome 2 open reading frame 72
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CIITA class II, major histocompatibility complex, transactivator
COL5A2 collagen, type V, alpha 2
COPE coatomer protein complex, subunit epsilon
DCSTAMP dendrocyte expressed seven transmembrane protein
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DMPK dystrophia myotonica-protein kinase
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DZIP1 DAZ interacting zinc finger protein 1
E2F5 E2F transcription factor 5, p130-binding
EGR1 early growth response 1
EMID1 EMI domain containing 1
EPYC epiphycan
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAM129A family with sequence similarity 129, member A
FBN1 fibrillin 1
FHIT fragile histidine triad
FOS FBJ murine osteosarcoma viral oncogene homolog
GBP1 guanylate binding protein 1, interferon-inducible
GLB1L galactosidase, beta 1-like
GPR3 G protein-coupled receptor 3
GRK5 G protein-coupled receptor kinase 5
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
KIAA1467 KIAA1467
KLF6 Kruppel-like factor 6
KRT32 keratin 32, type I
LAMC2 laminin, gamma 2
LARP6 La ribonucleoprotein domain family, member 6
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LUZP4 leucine zipper protein 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MT1G metallothionein 1G
MTL5 metallothionein-like 5, testis-specific (tesmin)
MXD4 MAX dimerization protein 4
NCKIPSD NCK interacting protein with SH3 domain
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR2F2 olfactory receptor, family 2, subfamily F, member 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PER1 period circadian clock 1
PGR progesterone receptor
PLEC plectin
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK3 polo-like kinase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLL polymerase (DNA directed), lambda
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRSS53 protease, serine, 53
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PWAR5 Prader Willi/Angelman region RNA 5
RABGAP1 RAB GTPase activating protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS5 regulator of G-protein signaling 5
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SARDH sarcosine dehydrogenase
SAYSD1 SAYSVFN motif domain containing 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TTPA tocopherol (alpha) transfer protein
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTL8 actin-like 8
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D2 B9 protein domain 2
C17ORF53 chromosome 17 open reading frame 53
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CD3D CD3d molecule, delta (CD3-TCR complex)
CD82 CD82 molecule
CIC capicua transcriptional repressor
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPB1 carboxypeptidase B1 (tissue)
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOK5 docking protein 5
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPX eosinophil peroxidase
F2R coagulation factor II (thrombin) receptor
FAM76A family with sequence similarity 76, member A
FBRS fibrosin
FBXO2 F-box protein 2
FBXO4 F-box protein 4
FLJ22184
FRMD1 FERM domain containing 1
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR157 G protein-coupled receptor 157
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL28 kelch-like family member 28
LOXL3 lysyl oxidase-like 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MED24 mediator complex subunit 24
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MTCP1 mature T-cell proliferation 1
NDOR1 NADPH dependent diflavin oxidoreductase 1
NECAP2 NECAP endocytosis associated 2
NME5 NME/NM23 family member 5
OCA2 oculocutaneous albinism II
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PCDHB8 protocadherin beta 8
PGP phosphoglycolate phosphatase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLCD1 phospholipase C, delta 1
PLSCR4 phospholipid scramblase 4
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POM121 POM121 transmembrane nucleoporin
PP14571 uncharacterized LOC100130449
PSKH1 protein serine kinase H1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF122 ring finger protein 122
RNF208 ring finger protein 208
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLIT2 slit homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMCC2 transmembrane and coiled-coil domain family 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC33 tetratricopeptide repeat domain 33
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR4 WD repeat domain 4
ZBTB22 zinc finger and BTB domain containing 22
ZMYM3 zinc finger, MYM-type 3
ZSWIM1 zinc finger, SWIM-type containing 1