tight junction assembly Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. (Gene Ontology, GO_0070830)
External Link http://amigo.geneontology.org/amigo/term/GO:0120192
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Genes

55 genes participating in the tight junction assembly biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACTG1 actin gamma 1
AFDN afadin, adherens junction formation factor
ARL2 ADP-ribosylation factor-like 2
CDH5 cadherin 5, type 2 (vascular endothelium)
CLDN1 claudin 1
CLDN10 claudin 10
CLDN11 claudin 11
CLDN12 claudin 12
CLDN14 claudin 14
CLDN15 claudin 15
CLDN16 claudin 16
CLDN17 claudin 17
CLDN18 claudin 18
CLDN19 claudin 19
CLDN2 claudin 2
CLDN20 claudin 20
CLDN22 claudin 22
CLDN23 claudin 23
CLDN24 claudin 24
CLDN25 claudin 25
CLDN3 claudin 3
CLDN34 claudin 34
CLDN4 claudin 4
CLDN5 claudin 5
CLDN6 claudin 6
CLDN7 claudin 7
CLDN8 claudin 8
CLDN9 claudin 9
DLG1 discs, large homolog 1 (Drosophila)
DSG3 desmoglein 3
ECT2 epithelial cell transforming 2
ESAM endothelial cell adhesion molecule
FRMPD2 FERM and PDZ domain containing 2
GRHL2 grainyhead-like 2 (Drosophila)
ILDR1 immunoglobulin-like domain containing receptor 1
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LSR lipolysis stimulated lipoprotein receptor
MARVELD2 MARVEL domain containing 2
MARVELD3 MARVEL domain containing 3
MICALL2 MICAL-like 2
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
OCEL1 occludin/ELL domain containing 1
OCLN occludin
PARD3 par-3 family cell polarity regulator
PATJ PATJ crumbs cell polarity complex component
PDCD6IP programmed cell death 6 interacting protein
PECAM1 platelet/endothelial cell adhesion molecule 1
PKN2 protein kinase N2
POF1B premature ovarian failure, 1B
PROC protein C (inactivator of coagulation factors Va and VIIIa)
RAB13 RAB13, member RAS oncogene family
RAMP2 receptor (G protein-coupled) activity modifying protein 2
SLC39A9 solute carrier family 39, member 9
STRN striatin, calmodulin binding protein
TBCD tubulin folding cofactor D