tiletamine-6013 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the tiletamine-6013 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AK1 adenylate kinase 1
AKAP13 A kinase (PRKA) anchor protein 13
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BAHCC1 BAH domain and coiled-coil containing 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BDNF brain-derived neurotrophic factor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCRL2 chemokine (C-C motif) receptor-like 2
CDHR2 cadherin-related family member 2
CEP164 centrosomal protein 164kDa
CFAP70 cilia and flagella associated protein 70
CHN2 chimerin 2
COL6A1 collagen, type VI, alpha 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYTH4 cytohesin 4
DCTN2 dynactin 2 (p50)
DSC1 desmocollin 1
DTNA dystrobrevin, alpha
DZIP1 DAZ interacting zinc finger protein 1
EGR1 early growth response 1
ESM1 endothelial cell-specific molecule 1
EXTL3 exostosin-like glycosyltransferase 3
FAM134B family with sequence similarity 134, member B
FHIT fragile histidine triad
FHL5 four and a half LIM domains 5
FSCN1 fascin actin-bundling protein 1
GAP43 growth associated protein 43
GAS7 growth arrest-specific 7
GDF2 growth differentiation factor 2
GLB1L galactosidase, beta 1-like
GPRC5D G protein-coupled receptor, class C, group 5, member D
HBS1L HBS1-like translational GTPase
HIST1H2BB histone cluster 1, H2bb
HLA-DOA major histocompatibility complex, class II, DO alpha
HMGN5 high mobility group nucleosome binding domain 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITGA7 integrin, alpha 7
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMA4 laminin, alpha 4
LAT2 linker for activation of T cells family, member 2
LEPR leptin receptor
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MC3R melanocortin 3 receptor
MCTP1 multiple C2 domains, transmembrane 1
MED16 mediator complex subunit 16
MEGF6 multiple EGF-like-domains 6
MOCS1 molybdenum cofactor synthesis 1
N4BP2L1 NEDD4 binding protein 2-like 1
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NUP214 nucleoporin 214kDa
PCDHB13 protocadherin beta 13
PCDHGA11 protocadherin gamma subfamily A, 11
PCSK6 proprotein convertase subtilisin/kexin type 6
PGK1 phosphoglycerate kinase 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLK3 polo-like kinase 3
PRTN3 proteinase 3
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB14 RAB14, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RIMS2 regulating synaptic membrane exocytosis 2
RNF122 ring finger protein 122
RTEL1 regulator of telomere elongation helicase 1
RUNDC3B RUN domain containing 3B
SH3BP2 SH3-domain binding protein 2
SIM2 single-minded family bHLH transcription factor 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC43A3 solute carrier family 43, member 3
SMC1A structural maintenance of chromosomes 1A
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPPL2B signal peptide peptidase like 2B
SPTBN1 spectrin, beta, non-erythrocytic 1
SSTR4 somatostatin receptor 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUGP1 SURP and G patch domain containing 1
SYT5 synaptotagmin V
TAPBP TAP binding protein (tapasin)
TBC1D2 TBC1 domain family, member 2
TCEAL2 transcription elongation factor A (SII)-like 2
TGM4 transglutaminase 4
TPMT thiopurine S-methyltransferase
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBE3A ubiquitin protein ligase E3A
UBOX5 U-box domain containing 5
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VWA5A von Willebrand factor A domain containing 5A
WIZ widely interspaced zinc finger motifs
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
AKT2 v-akt murine thymoma viral oncogene homolog 2
APLP1 amyloid beta (A4) precursor-like protein 1
ATAD5 ATPase family, AAA domain containing 5
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBC3 BCL2 binding component 3
C14ORF132 chromosome 14 open reading frame 132
C14ORF93 chromosome 14 open reading frame 93
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C6ORF47 chromosome 6 open reading frame 47
CAMTA2 calmodulin binding transcription activator 2
CASZ1 castor zinc finger 1
CCNO cyclin O
CHKB choline kinase beta
CSF1R colony stimulating factor 1 receptor
CXXC4 CXXC finger protein 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFHD2 EF-hand domain family, member D2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM120C family with sequence similarity 120C
FAM155B family with sequence similarity 155, member B
FBXO22 F-box protein 22
FKBP10 FK506 binding protein 10, 65 kDa
FKBP8 FK506 binding protein 8, 38kDa
FLCN folliculin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPC3 glypican 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2AI histone cluster 1, H2ai
HIST1H4F histone cluster 1, H4f
HOMER2 homer scaffolding protein 2
HPS6 Hermansky-Pudlak syndrome 6
IFT22 intraflagellar transport 22
IGFLR1 IGF-like family receptor 1
INF2 inverted formin, FH2 and WH2 domain containing
IQCE IQ motif containing E
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KIAA0355 KIAA0355
KIAA0922 KIAA0922
KLF2 Kruppel-like factor 2
KPTN kaptin (actin binding protein)
LPXN leupaxin
MAST3 microtubule associated serine/threonine kinase 3
MID1IP1 MID1 interacting protein 1
MRAS muscle RAS oncogene homolog
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACS1 phosphofurin acidic cluster sorting protein 1
PC pyruvate carboxylase
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PRAF2 PRA1 domain family, member 2
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PTDSS2 phosphatidylserine synthase 2
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3D RAB3D, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFXAP regulatory factor X-associated protein
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RLN1 relaxin 1
RNF167 ring finger protein 167
RNF2 ring finger protein 2
SAMD9 sterile alpha motif domain containing 9
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SLC10A3 solute carrier family 10, member 3
SLC12A8 solute carrier family 12, member 8
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOCS2 suppressor of cytokine signaling 2
SP1 Sp1 transcription factor
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRYD7 SPRY domain containing 7
SSBP3 single stranded DNA binding protein 3
SUN2 Sad1 and UNC84 domain containing 2
TAGLN transgelin
TBC1D17 TBC1 domain family, member 17
TEAD3 TEA domain family member 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLN1 talin 1
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UNC119 unc-119 homolog (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFB vascular endothelial growth factor B
VLDLR very low density lipoprotein receptor
VNN2 vanin 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBTB48 zinc finger and BTB domain containing 48
ZNF862 zinc finger protein 862