tiletamine-7311 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tiletamine-7311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABHD2 abhydrolase domain containing 2
ACVR1B activin A receptor, type IB
AGMAT agmatine ureohydrolase (agmatinase)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP35 Rho GTPase activating protein 35
ARNT aryl hydrocarbon receptor nuclear translocator
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BRWD1 bromodomain and WD repeat domain containing 1
BTG2 BTG family, member 2
BTN3A1 butyrophilin, subfamily 3, member A1
C14ORF105 chromosome 14 open reading frame 105
C16ORF59 chromosome 16 open reading frame 59
C21ORF2 chromosome 21 open reading frame 2
CA9 carbonic anhydrase IX
CD4 CD4 molecule
CD58 CD58 molecule
CDK10 cyclin-dependent kinase 10
CDK3 cyclin-dependent kinase 3
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEP162 centrosomal protein 162kDa
CES3 carboxylesterase 3
COL21A1 collagen, type XXI, alpha 1
CXCL3 chemokine (C-X-C motif) ligand 3
FAM174B family with sequence similarity 174, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FGF1 fibroblast growth factor 1 (acidic)
FGFR1 fibroblast growth factor receptor 1
FLJ11292
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA4 homeobox A4
INPP5J inositol polyphosphate-5-phosphatase J
IPO8 importin 8
JAG2 jagged 2
JMJD6 jumonji domain containing 6
KIF13A kinesin family member 13A
KLHL20 kelch-like family member 20
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LINC00260 long intergenic non-protein coding RNA 260
LRRC61 leucine rich repeat containing 61
MAP7 microtubule-associated protein 7
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MIIP migration and invasion inhibitory protein
MLX MLX, MAX dimerization protein
MTRF1L mitochondrial translational release factor 1-like
MTUS1 microtubule associated tumor suppressor 1
NGDN neuroguidin, EIF4E binding protein
NINJ1 ninjurin 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRCAM neuronal cell adhesion molecule
PALM paralemmin
PARM1 prostate androgen-regulated mucin-like protein 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PICALM phosphatidylinositol binding clathrin assembly protein
PKP3 plakophilin 3
PLA2G3 phospholipase A2, group III
PLCH1 phospholipase C, eta 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAP1GAP RAP1 GTPase activating protein
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REST RE1-silencing transcription factor
RNF122 ring finger protein 122
RRAGB Ras-related GTP binding B
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCAPER S-phase cyclin A-associated protein in the ER
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SIRT6 sirtuin 6
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SPTAN1 spectrin, alpha, non-erythrocytic 1
STRA6 stimulated by retinoic acid 6
SYNE1 spectrin repeat containing, nuclear envelope 1
SYT17 synaptotagmin XVII
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCOF1 Treacher Collins-Franceschetti syndrome 1
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOP3A topoisomerase (DNA) III alpha
TRAF4 TNF receptor-associated factor 4
TUSC3 tumor suppressor candidate 3
UBOX5 U-box domain containing 5
ZER1 zyg-11 related, cell cycle regulator
ZNF224 zinc finger protein 224
ZNF286A zinc finger protein 286A
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD36 ankyrin repeat domain 36
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARMCX2 armadillo repeat containing, X-linked 2
ATAD2B ATPase family, AAA domain containing 2B
AUNIP aurora kinase A and ninein interacting protein
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF56 chromosome 1 open reading frame 56
C3ORF52 chromosome 3 open reading frame 52
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CAPN5 calpain 5
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCP110 centriolar coiled coil protein 110kDa
CCRL2 chemokine (C-C motif) receptor-like 2
CEP97 centrosomal protein 97kDa
CFAP69 cilia and flagella associated protein 69
CINP cyclin-dependent kinase 2 interacting protein
CNGB3 cyclic nucleotide gated channel beta 3
COQ4 coenzyme Q4
CST6 cystatin E/M
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLK1 delta-like 1 homolog (Drosophila)
DNMBP dynamin binding protein
EFCAB2 EF-hand calcium binding domain 2
ELOVL4 ELOVL fatty acid elongase 4
EPN3 epsin 3
ERN2 endoplasmic reticulum to nucleus signaling 2
F3 coagulation factor III (thromboplastin, tissue factor)
FAM53B family with sequence similarity 53, member B
FBXL15 F-box and leucine-rich repeat protein 15
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR3 G protein-coupled receptor 3
HDAC4 histone deacetylase 4
HIST1H3G histone cluster 1, H3g
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOMER2 homer scaffolding protein 2
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ISYNA1 inositol-3-phosphate synthase 1
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF13 Kruppel-like factor 13
KPTN kaptin (actin binding protein)
LYPD1 LY6/PLAUR domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MED15 mediator complex subunit 15
MED9 mediator complex subunit 9
MFGE8 milk fat globule-EGF factor 8 protein
MLYCD malonyl-CoA decarboxylase
MMP13 matrix metallopeptidase 13
MNS1 meiosis-specific nuclear structural 1
MNX1 motor neuron and pancreas homeobox 1
MOXD1 monooxygenase, DBH-like 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MX1 MX dynamin-like GTPase 1
MYL5 myosin, light chain 5, regulatory
NXPH4 neurexophilin 4
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae)
PARD6A par-6 family cell polarity regulator alpha
PCDHGB5 protocadherin gamma subfamily B, 5
POU2F1 POU class 2 homeobox 1
PTK6 protein tyrosine kinase 6
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SFT2D2 SFT2 domain containing 2
SIPA1 signal-induced proliferation-associated 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SRD5A3 steroid 5 alpha-reductase 3
STAR steroidogenic acute regulatory protein
STX1A syntaxin 1A (brain)
TBP TATA box binding protein
TBXAS1 thromboxane A synthase 1 (platelet)
TDRD7 tudor domain containing 7
THOP1 thimet oligopeptidase 1
TM7SF2 transmembrane 7 superfamily member 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR19 WD repeat domain 19
YY2 YY2 transcription factor
ZNF180 zinc finger protein 180
ZNF37BP zinc finger protein 37B, pseudogene
ZNF8 zinc finger protein 8
ZNHIT2 zinc finger, HIT-type containing 2