| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the timolol-4685 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM1L | absent in melanoma 1-like |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ART1 | ADP-ribosyltransferase 1 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| B9D1 | B9 protein domain 1 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BEX1 | brain expressed, X-linked 1 |
| CCNJ | cyclin J |
| CEP295 | centrosomal protein 295kDa |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CSF1R | colony stimulating factor 1 receptor |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DCAF11 | DDB1 and CUL4 associated factor 11 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DKFZP434L187 | uncharacterized LOC26082 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ECE1 | endothelin converting enzyme 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV1 | ets variant 1 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM63B | family with sequence similarity 63, member B |
| FDPS | farnesyl diphosphate synthase |
| FKRP | fukutin related protein |
| FZD1 | frizzled class receptor 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GOLGA2 | golgin A2 |
| GPR21 | G protein-coupled receptor 21 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOMER3 | homer scaffolding protein 3 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LAMC2 | laminin, gamma 2 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| MAP1B | microtubule-associated protein 1B |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MDFIC | MyoD family inhibitor domain containing |
| MEF2C | myocyte enhancer factor 2C |
| MUC4 | mucin 4, cell surface associated |
| NEK9 | NIMA-related kinase 9 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NRL | neural retina leucine zipper |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OGFR | opioid growth factor receptor |
| PAQR5 | progestin and adipoQ receptor family member V |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PAX9 | paired box 9 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PITX1 | paired-like homeodomain 1 |
| PKN2 | protein kinase N2 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| PVR | poliovirus receptor |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STS | steroid sulfatase (microsomal), isozyme S |
| STX7 | syntaxin 7 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TP63 | tumor protein p63 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| TUBA3C | tubulin, alpha 3c |
| VASH1 | vasohibin 1 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF215 | zinc finger protein 215 |
| ZNF268 | zinc finger protein 268 |
| ZNF695 | zinc finger protein 695 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AMT | aminomethyltransferase |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC85C | coiled-coil domain containing 85C |
| CD68 | CD68 molecule |
| CEL | carboxyl ester lipase |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CNN1 | calponin 1, basic, smooth muscle |
| COL7A1 | collagen, type VII, alpha 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| ELMO3 | engulfment and cell motility 3 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FMO4 | flavin containing monooxygenase 4 |
| FRMD8 | FERM domain containing 8 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR1 | G protein-coupled receptor 1 |
| GPR27 | G protein-coupled receptor 27 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H3I | histone cluster 1, H3i |
| HSPA1L | heat shock 70kDa protein 1-like |
| IFT54 | intraflagellar transport 54 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL24 | interleukin 24 |
| IL32 | interleukin 32 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB7 | integrin, beta 7 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KRT20 | keratin 20, type I |
| KRT31 | keratin 31, type I |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00472 | long intergenic non-protein coding RNA 472 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY96 | lymphocyte antigen 96 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MDFI | MyoD family inhibitor |
| MGP | matrix Gla protein |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3B | mucin 3B, cell surface associated |
| MYOZ3 | myozenin 3 |
| NID2 | nidogen 2 (osteonidogen) |
| NTF3 | neurotrophin 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OCA2 | oculocutaneous albinism II |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE11A | phosphodiesterase 11A |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRM2 | protamine 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF2 | ring finger protein 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAI | suppressor of cancer cell invasion |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SFTPA2 | surfactant protein A2 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPATA1 | spermatogenesis associated 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TMEM40 | transmembrane protein 40 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF428 | zinc finger protein 428 |
| ZNF529 | zinc finger protein 529 |
