| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the timolol-5280 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT11 | acyl-CoA thioesterase 11 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADAM29 | ADAM metallopeptidase domain 29 |
| AHSP | alpha hemoglobin stabilizing protein |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALPPL2 | alkaline phosphatase, placental-like 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ATG10 | autophagy related 10 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BST2 | bone marrow stromal cell antigen 2 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CA9 | carbonic anhydrase IX |
| CHI3L2 | chitinase 3-like 2 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLCA2 | chloride channel accessory 2 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CTSF | cathepsin F |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DMXL2 | Dmx-like 2 |
| DOCK9 | dedicator of cytokinesis 9 |
| DVL2 | dishevelled segment polarity protein 2 |
| EFNA5 | ephrin-A5 |
| EHD2 | EH-domain containing 2 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FBXO41 | F-box protein 41 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLJ11292 | |
| FOXG1 | forkhead box G1 |
| FRMD8 | FERM domain containing 8 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GAS7 | growth arrest-specific 7 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPR137 | G protein-coupled receptor 137 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIST1H2AB | histone cluster 1, H2ab |
| HLF | hepatic leukemia factor |
| HNMT | histamine N-methyltransferase |
| HPX | hemopexin |
| IFFO1 | intermediate filament family orphan 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KIF25 | kinesin family member 25 |
| LAMB4 | laminin, beta 4 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MED25 | mediator complex subunit 25 |
| METTL7A | methyltransferase like 7A |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| NF1 | neurofibromin 1 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NRF1 | nuclear respiratory factor 1 |
| NUP54 | nucleoporin 54kDa |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OLFML2A | olfactomedin-like 2A |
| PDE10A | phosphodiesterase 10A |
| PDLIM5 | PDZ and LIM domain 5 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLCL2 | phospholipase C-like 2 |
| PLXDC1 | plexin domain containing 1 |
| POU5F1B | POU class 5 homeobox 1B |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCE | protein kinase C, epsilon |
| PYY | peptide YY |
| RAB40C | RAB40C, member RAS oncogene family |
| RAP2B | RAP2B, member of RAS oncogene family |
| RBM48 | RNA binding motif protein 48 |
| RETN | resistin |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RNF17 | ring finger protein 17 |
| RPL35A | ribosomal protein L35a |
| RUNDC3A | RUN domain containing 3A |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SSTR4 | somatostatin receptor 4 |
| TBC1D22A | TBC1 domain family, member 22A |
| TMEM212 | transmembrane protein 212 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ACTL8 | actin-like 8 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BMP15 | bone morphogenetic protein 15 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK6 | cyclin-dependent kinase 6 |
| CFAP69 | cilia and flagella associated protein 69 |
| CLGN | calmegin |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DRD1 | dopamine receptor D1 |
| DUSP13 | dual specificity phosphatase 13 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDN1 | endothelin 1 |
| EN2 | engrailed homeobox 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV6 | ets variant 6 |
| FER | fer (fps/fes related) tyrosine kinase |
| FFAR2 | free fatty acid receptor 2 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTA4 | glutathione S-transferase alpha 4 |
| GSTP1 | glutathione S-transferase pi 1 |
| HIST1H1D | histone cluster 1, H1d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL4R | interleukin 4 receptor |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIF5A | kinesin family member 5A |
| KLHL25 | kelch-like family member 25 |
| KRT15 | keratin 15, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LENEP | lens epithelial protein |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC729164 | hCG1732469 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAOB | monoamine oxidase B |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MMP3 | matrix metallopeptidase 3 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| NAG18 | NAG18 mRNA |
| NOL12 | nucleolar protein 12 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PCDHB8 | protocadherin beta 8 |
| PENK | proenkephalin |
| PGR | progesterone receptor |
| PICK1 | protein interacting with PRKCA 1 |
| PIPOX | pipecolic acid oxidase |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RELN | reelin |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RPA4 | replication protein A4, 30kDa |
| S100A2 | S100 calcium binding protein A2 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCHIP1 | schwannomin interacting protein 1 |
| SDS | serine dehydratase |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A14 | solute carrier family 22, member 14 |
| SPRR2B | small proline-rich protein 2B |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| STBD1 | starch binding domain 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TARP | TCR gamma alternate reading frame protein |
| TBC1D19 | TBC1 domain family, member 19 |
| TEX14 | testis expressed 14 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TMEM242 | transmembrane protein 242 |
| TUBA4B | tubulin, alpha 4b |
| UBXN6 | UBX domain protein 6 |
| UPP1 | uridine phosphorylase 1 |
| WBP2 | WW domain binding protein 2 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF34 | zinc finger protein 34 |
| ZNF480 | zinc finger protein 480 |
| ZNF750 | zinc finger protein 750 |
