| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the timolol-5645 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATN1 | atrophin 1 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BARX2 | BARX homeobox 2 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CADM4 | cell adhesion molecule 4 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CRB1 | crumbs family member 1, photoreceptor morphogenesis associated |
| CTAG2 | cancer/testis antigen 2 |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYP2C8 | cytochrome P450, family 2, subfamily C, polypeptide 8 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DCTN1 | dynactin 1 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DOCK10 | dedicator of cytokinesis 10 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EFNB3 | ephrin-B3 |
| EPHA5 | EPH receptor A5 |
| EXOC7 | exocyst complex component 7 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FCMR | Fc fragment of IgM receptor |
| FGF22 | fibroblast growth factor 22 |
| FPR2 | formyl peptide receptor 2 |
| FRZB | frizzled-related protein |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT9 | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GGT1 | gamma-glutamyltransferase 1 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HHLA1 | HERV-H LTR-associating 1 |
| ITGB8 | integrin, beta 8 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KIF25 | kinesin family member 25 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLHL25 | kelch-like family member 25 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KSR1 | kinase suppressor of ras 1 |
| LAMB4 | laminin, beta 4 |
| LATS1 | large tumor suppressor kinase 1 |
| MAOA | monoamine oxidase A |
| MTCP1 | mature T-cell proliferation 1 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXRA5 | matrix-remodelling associated 5 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| MYOZ1 | myozenin 1 |
| NAG18 | NAG18 mRNA |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| PCDH12 | protocadherin 12 |
| PDAP1 | PDGFA associated protein 1 |
| PEG10 | paternally expressed 10 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| PTAFR | platelet-activating factor receptor |
| RFPL1S | RFPL1 antisense RNA 1 |
| RPS3A | ribosomal protein S3A |
| SCARF1 | scavenger receptor class F, member 1 |
| SCRT1 | scratch family zinc finger 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPAG6 | sperm associated antigen 6 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAPBP | TAP binding protein (tapasin) |
| THRB | thyroid hormone receptor, beta |
| TRIM15 | tripartite motif containing 15 |
| TRPM8 | transient receptor potential cation channel, subfamily M, member 8 |
| UBOX5 | U-box domain containing 5 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WSCD1 | WSC domain containing 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF280A | zinc finger protein 280A |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| BMP15 | bone morphogenetic protein 15 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CA11 | carbonic anhydrase XI |
| CABP2 | calcium binding protein 2 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CEP97 | centrosomal protein 97kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CLGN | calmegin |
| CLIC2 | chloride intracellular channel 2 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRLF1 | cytokine receptor-like factor 1 |
| CSTA | cystatin A (stefin A) |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DSPP | dentin sialophosphoprotein |
| EDAR | ectodysplasin A receptor |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPN1 | epsin 1 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FILIP1L | filamin A interacting protein 1-like |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLJ22184 | |
| FRMD1 | FERM domain containing 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFI1 | growth factor independent 1 transcription repressor |
| GMPR | guanosine monophosphate reductase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4E | histone cluster 1, H4e |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0319L | KIAA0319-like |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLRAP1 | killer cell lectin-like receptor subfamily A pseudogene 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LOXL3 | lysyl oxidase-like 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MALL | mal, T-cell differentiation protein-like |
| N4BP3 | NEDD4 binding protein 3 |
| NCALD | neurocalcin delta |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OVOL1 | ovo-like zinc finger 1 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PODNL1 | podocan-like 1 |
| POLM | polymerase (DNA directed), mu |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRF1 | perforin 1 (pore forming protein) |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIN2 | Ras and Rab interactor 2 |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| RPH3A | rabphilin 3A |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RUNDC3B | RUN domain containing 3B |
| S100A7 | S100 calcium binding protein A7 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDS | serine dehydratase |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SSTR5 | somatostatin receptor 5 |
| STAB2 | stabilin 2 |
| TMEM19 | transmembrane protein 19 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VIM | vimentin |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| YY2 | YY2 transcription factor |
| ZNF134 | zinc finger protein 134 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF205 | zinc finger protein 205 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF551 | zinc finger protein 551 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |