| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the timolol-6483 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AOC3 | amine oxidase, copper containing 3 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BARX2 | BARX homeobox 2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CACTIN | cactin, spliceosome C complex subunit |
| CBLN1 | cerebellin 1 precursor |
| CD44 | CD44 molecule (Indian blood group) |
| CD52 | CD52 molecule |
| CLGN | calmegin |
| CNTN5 | contactin 5 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CST4 | cystatin S |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCTN2 | dynactin 2 (p50) |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DOCK6 | dedicator of cytokinesis 6 |
| DPP4 | dipeptidyl-peptidase 4 |
| EHD2 | EH-domain containing 2 |
| EMP1 | epithelial membrane protein 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPN1 | epsin 1 |
| FGB | fibrinogen beta chain |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GAB1 | GRB2-associated binding protein 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GPM6B | glycoprotein M6B |
| GPR21 | G protein-coupled receptor 21 |
| GPR22 | G protein-coupled receptor 22 |
| HBS1L | HBS1-like translational GTPase |
| HIST1H4F | histone cluster 1, H4f |
| HMG20B | high mobility group 20B |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like |
| HOXA11 | homeobox A11 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IHH | indian hedgehog |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL18 | interleukin 18 |
| IL2RG | interleukin 2 receptor, gamma |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0485 | uncharacterized LOC57235 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LIMK1 | LIM domain kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MTM1 | myotubularin 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| OMG | oligodendrocyte myelin glycoprotein |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PCDH1 | protocadherin 1 |
| PDE8B | phosphodiesterase 8B |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PML | promyelocytic leukemia |
| POFUT1 | protein O-fucosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SERPINB13 | serpin peptidase inhibitor, clade B (ovalbumin), member 13 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMAD6 | SMAD family member 6 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| TFR2 | transferrin receptor 2 |
| TMEM242 | transmembrane protein 242 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRBC1 | T cell receptor beta constant 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| ULBP2 | UL16 binding protein 2 |
| UNC5C | unc-5 homolog C (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMH | anti-Mullerian hormone |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOO | apolipoprotein O |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATXN2 | ataxin 2 |
| BAIAP3 | BAI1-associated protein 3 |
| BBC3 | BCL2 binding component 3 |
| BMP15 | bone morphogenetic protein 15 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CEP85 | centrosomal protein 85kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CLDN17 | claudin 17 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRY2 | cryptochrome circadian clock 2 |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DOK5 | docking protein 5 |
| EN2 | engrailed homeobox 2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM131A | family with sequence similarity 131, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO2 | F-box protein 2 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| GALK1 | galactokinase 1 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR3 | G protein-coupled receptor 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAMP | hepcidin antimicrobial peptide |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HDAC11 | histone deacetylase 11 |
| HIRA | histone cell cycle regulator |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3I | histone cluster 1, H3i |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| INTS9 | integrator complex subunit 9 |
| IPO8 | importin 8 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITGB7 | integrin, beta 7 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0894 | KIAA0894 protein |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| MYO1E | myosin IE |
| N4BP3 | NEDD4 binding protein 3 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NLGN1 | neuroligin 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| ONECUT2 | one cut homeobox 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PODNL1 | podocan-like 1 |
| POLL | polymerase (DNA directed), lambda |
| PRDM14 | PR domain containing 14 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN1 | tectonic family member 1 |
| TMEM183A | transmembrane protein 183A |
| TMEM62 | transmembrane protein 62 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNS2 | tensin 2 |
| TPCN1 | two pore segment channel 1 |
| TRIM49 | tripartite motif containing 49 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN4 | ubiquilin 4 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF204P | zinc finger protein 204, pseudogene |
| ZNF324 | zinc finger protein 324 |
| ZNF446 | zinc finger protein 446 |
| ZNF74 | zinc finger protein 74 |
