tinidazole-3430 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tinidazole-3430 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADAP1 ArfGAP with dual PH domains 1
ADM adrenomedullin
AJAP1 adherens junctions associated protein 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ANGPTL2 angiopoietin-like 2
ARID1A AT rich interactive domain 1A (SWI-like)
ASAP1-IT1 ASAP1 intronic transcript 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCDC85B coiled-coil domain containing 85B
CD58 CD58 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
E2F4 E2F transcription factor 4, p107/p130-binding
EMID1 EMI domain containing 1
FANCA Fanconi anemia, complementation group A
FLJ42627 uncharacterized LOC645644
FLOT2 flotillin 2
FRS2 fibroblast growth factor receptor substrate 2
FSCN1 fascin actin-bundling protein 1
GAL galanin/GMAP prepropeptide
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLRX3 glutaredoxin 3
GM2A GM2 ganglioside activator
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GREB1 growth regulation by estrogen in breast cancer 1
GSDMB gasdermin B
H2AFX H2A histone family, member X
HDAC5 histone deacetylase 5
HLA-C major histocompatibility complex, class I, C
HLA-J major histocompatibility complex, class I, J (pseudogene)
IGFALS insulin-like growth factor binding protein, acid labile subunit
IQCE IQ motif containing E
IQCK IQ motif containing K
JUNB jun B proto-oncogene
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KITLG KIT ligand
KLHL25 kelch-like family member 25
LAT2 linker for activation of T cells family, member 2
LEPR leptin receptor
LINC00260 long intergenic non-protein coding RNA 260
LMNB1 lamin B1
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MARK4 MAP/microtubule affinity-regulating kinase 4
MEFV Mediterranean fever
MERTK MER proto-oncogene, tyrosine kinase
METTL16 methyltransferase like 16
NGLY1 N-glycanase 1
NOL10 nucleolar protein 10
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYNRIN NYN domain and retroviral integrase containing
ORC5 origin recognition complex, subunit 5
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAUR plasminogen activator, urokinase receptor
PTPN21 protein tyrosine phosphatase, non-receptor type 21
QPCTL glutaminyl-peptide cyclotransferase-like
RABGAP1 RAB GTPase activating protein 1
RNF6 ring finger protein (C3H2C3 type) 6
RPL10 ribosomal protein L10
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A6 S100 calcium binding protein A6
SCD5 stearoyl-CoA desaturase 5
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SGSM3 small G protein signaling modulator 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SOCS6 suppressor of cytokine signaling 6
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D22A TBC1 domain family, member 22A
TIMELESS timeless circadian clock
TM4SF1 transmembrane 4 L six family member 1
UPP1 uridine phosphorylase 1
USP20 ubiquitin specific peptidase 20
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WSCD1 WSC domain containing 1
YIPF2 Yip1 domain family, member 2
YPEL1 yippee-like 1 (Drosophila)
ZBTB7A zinc finger and BTB domain containing 7A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF444 zinc finger protein 444
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGAP10 Rho GTPase activating protein 10
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARSB arylsulfatase B
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AUNIP aurora kinase A and ninein interacting protein
B9D2 B9 protein domain 2
BAK1 BCL2-antagonist/killer 1
BBS10 Bardet-Biedl syndrome 10
BCL2L2 BCL2-like 2
BCL9 B-cell CLL/lymphoma 9
BFSP1 beaded filament structural protein 1, filensin
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CCDC9 coiled-coil domain containing 9
CEP131 centrosomal protein 131kDa
CEP170B centrosomal protein 170B
CEP97 centrosomal protein 97kDa
CLCN2 chloride channel, voltage-sensitive 2
CLSPN claspin
DCAF13 DDB1 and CUL4 associated factor 13
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FAM169A family with sequence similarity 169, member A
FAM50B family with sequence similarity 50, member B
FBXW12 F-box and WD repeat domain containing 12
GMEB1 glucocorticoid modulatory element binding protein 1
GMIP GEM interacting protein
GPRASP1 G protein-coupled receptor associated sorting protein 1
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2BJ histone cluster 1, H2bj
IFT81 intraflagellar transport 81
IMPACT impact RWD domain protein
IRF9 interferon regulatory factor 9
JADE3 jade family PHD finger 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KRT13 keratin 13, type I
LAMB1 laminin, beta 1
LINC00339 long intergenic non-protein coding RNA 339
LMCD1 LIM and cysteine-rich domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC49 leucine rich repeat containing 49
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAPK12 mitogen-activated protein kinase 12
MGC12488
MT1H metallothionein 1H
MUL1 mitochondrial E3 ubiquitin protein ligase 1
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NR2C2 nuclear receptor subfamily 2, group C, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
P3H1 prolyl 3-hydroxylase 1
PAQR4 progestin and adipoQ receptor family member IV
PARG poly (ADP-ribose) glycohydrolase
PKN1 protein kinase N1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROCR protein C receptor, endothelial
RAD51B RAD51 paralog B
RASAL1 RAS protein activator like 1 (GAP1 like)
RFTN1 raftlin, lipid raft linker 1
RNF123 ring finger protein 123
RPAP1 RNA polymerase II associated protein 1
RRAGB Ras-related GTP binding B
SH2B3 SH2B adaptor protein 3
SIRT2 sirtuin 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35E3 solute carrier family 35, member E3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX17 syntaxin 17
SYT17 synaptotagmin XVII
TMEM183A transmembrane protein 183A
TMPRSS3 transmembrane protease, serine 3
TRAF2 TNF receptor-associated factor 2
TRIM5 tripartite motif containing 5
URGCP upregulator of cell proliferation
VEGFC vascular endothelial growth factor C
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XYLT2 xylosyltransferase II
ZNF451 zinc finger protein 451
ZNF532 zinc finger protein 532
ZNF574 zinc finger protein 574
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862
ZSCAN26 zinc finger and SCAN domain containing 26