tinidazole-3813 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the tinidazole-3813 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACAA2 acetyl-CoA acyltransferase 2
ADRBK2 adrenergic, beta, receptor kinase 2
AGBL3 ATP/GTP binding protein-like 3
AKAP5 A kinase (PRKA) anchor protein 5
ANGPTL2 angiopoietin-like 2
ASIC1 acid sensing (proton gated) ion channel 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BIRC7 baculoviral IAP repeat containing 7
BRS3 bombesin-like receptor 3
BTBD18 BTB (POZ) domain containing 18
BTN3A2 butyrophilin, subfamily 3, member A2
CADM1 cell adhesion molecule 1
CCL13 chemokine (C-C motif) ligand 13
CD248 CD248 molecule, endosialin
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFH complement factor H
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLTA clathrin, light chain A
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CREBZF CREB/ATF bZIP transcription factor
CST4 cystatin S
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLX2 distal-less homeobox 2
DNAAF1 dynein, axonemal, assembly factor 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR2 estrogen receptor 2 (ER beta)
EYA3 EYA transcriptional coactivator and phosphatase 3
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAAH fatty acid amide hydrolase
FAM65B family with sequence similarity 65, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FXYD2 FXYD domain containing ion transport regulator 2
GALC galactosylceramidase
GOLGA6A golgin A6 family, member A
GP6 glycoprotein VI (platelet)
GPR135 G protein-coupled receptor 135
GRM7 glutamate receptor, metabotropic 7
HAL histidine ammonia-lyase
HCAR3 hydroxycarboxylic acid receptor 3
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL36RN interleukin 36 receptor antagonist
IL5RA interleukin 5 receptor, alpha
IQCC IQ motif containing C
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUND jun D proto-oncogene
KLHL22 kelch-like family member 22
KRTAP9-9 keratin associated protein 9-9
LDHC lactate dehydrogenase C
LPA lipoprotein, Lp(a)
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYEF2 myelin expression factor 2
NF1 neurofibromin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCDHGA10 protocadherin gamma subfamily A, 10
PF4 platelet factor 4
PGAP3 post-GPI attachment to proteins 3
PLD1 phospholipase D1, phosphatidylcholine-specific
PLVAP plasmalemma vesicle associated protein
PML promyelocytic leukemia
POM121L2 POM121 transmembrane nucleoporin-like 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PRB4 proline-rich protein BstNI subfamily 4
PSG6 pregnancy specific beta-1-glycoprotein 6
PTAFR platelet-activating factor receptor
PVT1 Pvt1 oncogene (non-protein coding)
RAB11B RAB11B, member RAS oncogene family
RASAL2 RAS protein activator like 2
REEP2 receptor accessory protein 2
RIN3 Ras and Rab interactor 3
SCN10A sodium channel, voltage gated, type X alpha subunit
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SRSF7 serine/arginine-rich splicing factor 7
SSX7 synovial sarcoma, X breakpoint 7
STAB1 stabilin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TBX6 T-box 6
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM144 transmembrane protein 144
TP53I11 tumor protein p53 inducible protein 11
TRAF3IP3 TRAF3 interacting protein 3
TRAPPC9 trafficking protein particle complex 9
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TTYH1 tweety family member 1
VWA5A von Willebrand factor A domain containing 5A
WNT3 wingless-type MMTV integration site family, member 3
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ACSS3 acyl-CoA synthetase short-chain family member 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANP32A-IT1 ANP32A intronic transcript 1
ANXA10 annexin A10
ANXA2P1 annexin A2 pseudogene 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATG10 autophagy related 10
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C3 complement component 3
CAMKMT calmodulin-lysine N-methyltransferase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD34 CD34 molecule
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLEC4E C-type lectin domain family 4, member E
COPZ2 coatomer protein complex, subunit zeta 2
CORO2A coronin, actin binding protein, 2A
CUZD1 CUB and zona pellucida-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYTH3 cytohesin 3
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
DNM3 dynamin 3
DSPP dentin sialophosphoprotein
EGFL7 EGF-like-domain, multiple 7
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERCC4 excision repair cross-complementation group 4
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM110B family with sequence similarity 110, member B
FAM63B family with sequence similarity 63, member B
FKBP5 FK506 binding protein 5
FSHB follicle stimulating hormone, beta polypeptide
GAS8 growth arrest-specific 8
GK3P glycerol kinase 3 pseudogene
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPNMB glycoprotein (transmembrane) nmb
GPR75 G protein-coupled receptor 75
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3C histone cluster 1, H3c
HIST1H3G histone cluster 1, H3g
HIST1H4B histone cluster 1, H4b
HOXC8 homeobox C8
IL33 interleukin 33
IPO8 importin 8
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KLHL25 kelch-like family member 25
LGALS4 lectin, galactoside-binding, soluble, 4
LIMD2 LIM domain containing 2
LOC729164 hCG1732469
LPAR3 lysophosphatidic acid receptor 3
LRP4 low density lipoprotein receptor-related protein 4
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAL mal, T-cell differentiation protein
MAP2 microtubule-associated protein 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
MMP10 matrix metallopeptidase 10
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NEUROD1 neuronal differentiation 1
NHEJ1 nonhomologous end-joining factor 1
NTNG1 netrin G1
OLFML2B olfactomedin-like 2B
OVGP1 oviductal glycoprotein 1, 120kDa
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAQR5 progestin and adipoQ receptor family member V
PAX9 paired box 9
POLH polymerase (DNA directed), eta
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTK6 protein tyrosine kinase 6
PWAR5 Prader Willi/Angelman region RNA 5
RPH3A rabphilin 3A
SCML2 sex comb on midleg-like 2 (Drosophila)
SLC16A6 solute carrier family 16, member 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TAGLN3 transgelin 3
TCEAL2 transcription elongation factor A (SII)-like 2
TET3 tet methylcytosine dioxygenase 3
TMEM206 transmembrane protein 206
TOR4A torsin family 4, member A
ZFP30 ZFP30 zinc finger protein
ZNF155 zinc finger protein 155
ZNF214 zinc finger protein 214
ZNF215 zinc finger protein 215
ZNF222 zinc finger protein 222
ZNF225 zinc finger protein 225
ZNF334 zinc finger protein 334
ZNF480 zinc finger protein 480
ZNF76 zinc finger protein 76
ZXDB zinc finger, X-linked, duplicated B