tinidazole-3896 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tinidazole-3896 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGFG1 ArfGAP with FG repeats 1
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ASIC1 acid sensing (proton gated) ion channel 1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BIN1 bridging integrator 1
C10ORF12 chromosome 10 open reading frame 12
C1ORF54 chromosome 1 open reading frame 54
C4ORF29 chromosome 4 open reading frame 29
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
DKFZP434C153 DKFZP434C153 protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
DUSP4 dual specificity phosphatase 4
EPB41L4A erythrocyte membrane protein band 4.1 like 4A
EPN2 epsin 2
FOXP3 forkhead box P3
GK glycerol kinase
GPR137 G protein-coupled receptor 137
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
H2AFX H2A histone family, member X
HDAC6 histone deacetylase 6
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIST3H3 histone cluster 3, H3
HPS4 Hermansky-Pudlak syndrome 4
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
INHBE inhibin, beta E
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB4 integrin, beta 4
ITGB6 integrin, beta 6
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD12 potassium channel tetramerization domain containing 12
KRT9 keratin 9, type I
L1CAM L1 cell adhesion molecule
LMAN1 lectin, mannose-binding, 1
LRP12 low density lipoprotein receptor-related protein 12
LRRC17 leucine rich repeat containing 17
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MTL5 metallothionein-like 5, testis-specific (tesmin)
NCDN neurochondrin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
NSUN7 NOP2/Sun domain family, member 7
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARVA parvin, alpha
PDE10A phosphodiesterase 10A
PDE12 phosphodiesterase 12
PHF20L1 PHD finger protein 20-like 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCH1 phospholipase C, eta 1
POU3F4 POU class 3 homeobox 4
PRKG2 protein kinase, cGMP-dependent, type II
RAB14 RAB14, member RAS oncogene family
SAYSD1 SAYSVFN motif domain containing 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SFTPD surfactant protein D
SH3BP1 SH3-domain binding protein 1
SLC16A4 solute carrier family 16, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMAD1 SMAD family member 1
SPATA2L spermatogenesis associated 2-like
SPN sialophorin
SUN1 Sad1 and UNC84 domain containing 1
TIMELESS timeless circadian clock
TIMP3 TIMP metallopeptidase inhibitor 3
TLX2 T-cell leukemia homeobox 2
TMPRSS4 transmembrane protease, serine 4
TRAPPC11 trafficking protein particle complex 11
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSC2 tuberous sclerosis 2
TTLL5 tubulin tyrosine ligase-like family member 5
UBXN1 UBX domain protein 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WASL Wiskott-Aldrich syndrome-like
WDFY3 WD repeat and FYVE domain containing 3
ZNF362 zinc finger protein 362
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
C2ORF27A chromosome 2 open reading frame 27A
CCDC85C coiled-coil domain containing 85C
CD82 CD82 molecule
CDK6 cyclin-dependent kinase 6
CNR2 cannabinoid receptor 2 (macrophage)
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CSTA cystatin A (stefin A)
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM2 dishevelled associated activator of morphogenesis 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGAT1 diacylglycerol O-acyltransferase 1
DLL3 delta-like 3 (Drosophila)
DPY19L1P1 DPY19L1 pseudogene 1
ENO3 enolase 3 (beta, muscle)
FAM155A family with sequence similarity 155, member A
FAT4 FAT atypical cadherin 4
FBXO31 F-box protein 31
FLJ22184
FMOD fibromodulin
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR39 G protein-coupled receptor 39
GRTP1 growth hormone regulated TBC protein 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IBSP integrin-binding sialoprotein
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRS4 insulin receptor substrate 4
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM8 lysine (K)-specific demethylase 8
KLHL25 kelch-like family member 25
KLK8 kallikrein-related peptidase 8
KRT13 keratin 13, type I
LRP2 low density lipoprotein receptor-related protein 2
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAGEB2 melanoma antigen family B2
MAOB monoamine oxidase B
MAPKBP1 mitogen-activated protein kinase binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MUC3B mucin 3B, cell surface associated
MYO1F myosin IF
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPPA natriuretic peptide A
NPTX1 neuronal pentraxin I
PGLYRP4 peptidoglycan recognition protein 4
PGR progesterone receptor
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PMCH pro-melanin-concentrating hormone
POMT2 protein-O-mannosyltransferase 2
RAB40AL RAB40A, member RAS oncogene family-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RHBG Rh family, B glycoprotein (gene/pseudogene)
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RSG1 REM2 and RAB-like small GTPase 1
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC41A3 solute carrier family 41, member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOAT2 sterol O-acyltransferase 2
SPON2 spondin 2, extracellular matrix protein
SYBU syntabulin (syntaxin-interacting)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCP10 t-complex 10
TCTN2 tectonic family member 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRB thyroid hormone receptor, beta
TICAM1 toll-like receptor adaptor molecule 1
TMEM40 transmembrane protein 40
TMEM8B transmembrane protein 8B
TMPRSS3 transmembrane protease, serine 3
TRIM36 tripartite motif containing 36
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
VIPR1 vasoactive intestinal peptide receptor 1
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
WNT16 wingless-type MMTV integration site family, member 16
XAB2 XPA binding protein 2
XDH xanthine dehydrogenase
YY2 YY2 transcription factor
ZNF219 zinc finger protein 219
ZNF639 zinc finger protein 639
ZSWIM1 zinc finger, SWIM-type containing 1