| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tinidazole-4370 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AGBL2 | ATP/GTP binding protein-like 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AJAP1 | adherens junctions associated protein 1 |
| ANKRD55 | ankyrin repeat domain 55 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOC1 | apolipoprotein C-I |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BIN1 | bridging integrator 1 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C3 | complement component 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCDC71 | coiled-coil domain containing 71 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD53 | CD53 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDHR2 | cadherin-related family member 2 |
| CFP | complement factor properdin |
| CLEC2D | C-type lectin domain family 2, member D |
| CSPG5 | chondroitin sulfate proteoglycan 5 (neuroglycan C) |
| FABP7 | fatty acid binding protein 7, brain |
| FGF16 | fibroblast growth factor 16 |
| FHL1 | four and a half LIM domains 1 |
| FRMD1 | FERM domain containing 1 |
| FRMD8 | FERM domain containing 8 |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPM6B | glycoprotein M6B |
| GPR35 | G protein-coupled receptor 35 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAB1 | B1 for mucin |
| HIST1H3I | histone cluster 1, H3i |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| ICOS | inducible T-cell co-stimulator |
| IL23A | interleukin 23, alpha subunit p19 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| IVL | involucrin |
| JAM2 | junctional adhesion molecule 2 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KEL | Kell blood group, metallo-endopeptidase |
| KLK13 | kallikrein-related peptidase 13 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT2 | keratin 2, type II |
| KRT75 | keratin 75, type II |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MBD2 | methyl-CpG binding domain protein 2 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MST1 | macrophage stimulating 1 |
| MUC3B | mucin 3B, cell surface associated |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOX3 | NADPH oxidase 3 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP188 | nucleoporin 188kDa |
| NUP88 | nucleoporin 88kDa |
| OGG1 | 8-oxoguanine DNA glycosylase |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta |
| PQLC2 | PQ loop repeat containing 2 |
| PRKCI | protein kinase C, iota |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RASIP1 | Ras interacting protein 1 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) |
| ROR2 | receptor tyrosine kinase-like orphan receptor 2 |
| RORA | RAR-related orphan receptor A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPON1 | spondin 1, extracellular matrix protein |
| STAB2 | stabilin 2 |
| STAC | SH3 and cysteine rich domain |
| STMN3 | stathmin-like 3 |
| STRN3 | striatin, calmodulin binding protein 3 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYT11 | synaptotagmin XI |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM29 | tripartite motif containing 29 |
| TSPAN32 | tetraspanin 32 |
| TTN | titin |
| VCL | vinculin |
| VPRBP | Vpr (HIV-1) binding protein |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF646 | zinc finger protein 646 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BLNK | B-cell linker |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBX2 | chromobox homolog 2 |
| CCDC69 | coiled-coil domain containing 69 |
| CCNO | cyclin O |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORO7 | coronin 7 |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEPDC5 | DEP domain containing 5 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNASE1L2 | deoxyribonuclease I-like 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM120C | family with sequence similarity 120C |
| FAM169A | family with sequence similarity 169, member A |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAS2 | growth arrest-specific 2 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR157 | G protein-coupled receptor 157 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GSTP1 | glutathione S-transferase pi 1 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1E | histone cluster 1, H1e |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IRF1 | interferon regulatory factor 1 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITM2C | integral membrane protein 2C |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF11 | Kruppel-like factor 11 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MEFV | Mediterranean fever |
| METTL2B | methyltransferase like 2B |
| MMP3 | matrix metallopeptidase 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPH4 | neurexophilin 4 |
| PCDHB3 | protocadherin beta 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PROCR | protein C receptor, endothelial |
| PVRL3 | poliovirus receptor-related 3 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RGS19 | regulator of G-protein signaling 19 |
| RNF208 | ring finger protein 208 |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A7 | S100 calcium binding protein A7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMIM14 | small integral membrane protein 14 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TEFM | transcription elongation factor, mitochondrial |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA4B | tubulin, alpha 4b |
| USB1 | U6 snRNA biogenesis 1 |
| VGF | VGF nerve growth factor inducible |
| VIM | vimentin |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF250 | zinc finger protein 250 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
| ZNF573 | zinc finger protein 573 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |