tiratricol-1412 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tiratricol-1412 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACACB acetyl-CoA carboxylase beta
ACTC1 actin, alpha, cardiac muscle 1
ACVR2A activin A receptor, type IIA
ADA adenosine deaminase
ADAM8 ADAM metallopeptidase domain 8
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOC1 apolipoprotein C-I
APOL6 apolipoprotein L, 6
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATG4B autophagy related 4B, cysteine peptidase
BAHCC1 BAH domain and coiled-coil containing 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF29 chromosome 22 open reading frame 29
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPRIN2 caprin family member 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBX6 chromobox homolog 6
CCDC71 coiled-coil domain containing 71
CD320 CD320 molecule
CES3 carboxylesterase 3
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN7 claudin 7
CROCC ciliary rootlet coiled-coil, rootletin
CRTC1 CREB regulated transcription coactivator 1
CYB561 cytochrome b561
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DUS2 dihydrouridine synthase 2
E2F4 E2F transcription factor 4, p107/p130-binding
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBXO42 F-box protein 42
FBXW4 F-box and WD repeat domain containing 4
FKBP9 FK506 binding protein 9, 63 kDa
FKBPL FK506 binding protein like
FMO4 flavin containing monooxygenase 4
FOXN3 forkhead box N3
GIPC1 GIPC PDZ domain containing family, member 1
GJB4 gap junction protein, beta 4, 30.3kDa
GLRX glutaredoxin (thioltransferase)
HEMK1 HemK methyltransferase family member 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT17 keratin 17, type I
LIN7A lin-7 homolog A (C. elegans)
LMO3 LIM domain only 3 (rhombotin-like 2)
LOC441601 septin 7 pseudogene
LPAR1 lysophosphatidic acid receptor 1
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1B1 mannosidase, alpha, class 1B, member 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MINK1 misshapen-like kinase 1
MLN motilin
MST1 macrophage stimulating 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSBPL10 oxysterol binding protein-like 10
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PARG poly (ADP-ribose) glycohydrolase
PARM1 prostate androgen-regulated mucin-like protein 1
PLD2 phospholipase D2
POFUT2 protein O-fucosyltransferase 2
PRDM2 PR domain containing 2, with ZNF domain
PRKCA protein kinase C, alpha
PTH1R parathyroid hormone 1 receptor
PTN pleiotrophin
RAB28 RAB28, member RAS oncogene family
RARB retinoic acid receptor, beta
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RGS10 regulator of G-protein signaling 10
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPL14 ribosomal protein L14
SAP30L SAP30-like
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFTPB surfactant protein B
SIGLEC5 sialic acid binding Ig-like lectin 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SMAD5 SMAD family member 5
STAT4 signal transducer and activator of transcription 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCP11L1 t-complex 11, testis-specific-like 1
TFE3 transcription factor binding to IGHM enhancer 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF2 transmembrane 7 superfamily member 2
TRIM14 tripartite motif containing 14
TSPAN13 tetraspanin 13
TTLL4 tubulin tyrosine ligase-like family member 4
UBOX5 U-box domain containing 5
UNC45A unc-45 homolog A (C. elegans)
VAC14 Vac14 homolog (S. cerevisiae)
VARS valyl-tRNA synthetase
WDR13 WD repeat domain 13
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF747 zinc finger protein 747
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADAT1 adenosine deaminase, tRNA-specific 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ASB8 ankyrin repeat and SOCS box containing 8
ATAD5 ATPase family, AAA domain containing 5
ATXN2 ataxin 2
BAK1 BCL2-antagonist/killer 1
BTK Bruton agammaglobulinemia tyrosine kinase
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CASD1 CAS1 domain containing 1
CCDC176 coiled-coil domain containing 176
CEND1 cell cycle exit and neuronal differentiation 1
CFAP74 cilia and flagella associated protein 74
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLTCL1 clathrin, heavy chain-like 1
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CRIPT cysteine-rich PDZ-binding protein
CSK c-src tyrosine kinase
CSNK1G3 casein kinase 1, gamma 3
CTRL chymotrypsin-like
CTSD cathepsin D
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBF4 DBF4 zinc finger
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
ECM1 extracellular matrix protein 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENAH enabled homolog (Drosophila)
ERF Ets2 repressor factor
EXOC5 exocyst complex component 5
FAM114A2 family with sequence similarity 114, member A2
FAM168B family with sequence similarity 168, member B
FANCF Fanconi anemia, complementation group F
FCHO1 FCH domain only 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GMCL1 germ cell-less, spermatogenesis associated 1
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GUSBP3 glucuronidase, beta pseudogene 3
HACD3 3-hydroxyacyl-CoA dehydratase 3
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFT88 intraflagellar transport 88
KCTD3 potassium channel tetramerization domain containing 3
KIAA1598
KIFC1 kinesin family member C1
KLHDC4 kelch domain containing 4
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LY75 lymphocyte antigen 75
MAP1S microtubule-associated protein 1S
MGAM maltase-glucoamylase
MIS18BP1 MIS18 binding protein 1
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MNS1 meiosis-specific nuclear structural 1
MPDU1 mannose-P-dolichol utilization defect 1
MPHOSPH8 M-phase phosphoprotein 8
MRPL33 mitochondrial ribosomal protein L33
MT1HL1 metallothionein 1H-like 1
NABP2 nucleic acid binding protein 2
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NT5DC3 5'-nucleotidase domain containing 3
NXPH3 neurexophilin 3
OCEL1 occludin/ELL domain containing 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PDIA3 protein disulfide isomerase family A, member 3
PEX26 peroxisomal biogenesis factor 26
PGLYRP4 peptidoglycan recognition protein 4
POMT1 protein-O-mannosyltransferase 1
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRR13 proline rich 13
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTX3 pentraxin 3, long
RPL39L ribosomal protein L39-like
RWDD3 RWD domain containing 3
SAMHD1 SAM domain and HD domain 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SESN1 sestrin 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SNX6 sorting nexin 6
STARD8 StAR-related lipid transfer (START) domain containing 8
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TJP2 tight junction protein 2
TMEM106B transmembrane protein 106B
TMEM14A transmembrane protein 14A
TMEM62 transmembrane protein 62
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBA3C tubulin, alpha 3c
UBP1 upstream binding protein 1 (LBP-1a)
WWC2 WW and C2 domain containing 2
ZEB2 zinc finger E-box binding homeobox 2
ZNF8 zinc finger protein 8
ZNHIT2 zinc finger, HIT-type containing 2