tiratricol-2096 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tiratricol-2096 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADGRF5 adhesion G protein-coupled receptor F5
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ANGPTL4 angiopoietin-like 4
ANKRD6 ankyrin repeat domain 6
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APLP2 amyloid beta (A4) precursor-like protein 2
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ASB7 ankyrin repeat and SOCS box containing 7
ASPH aspartate beta-hydroxylase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN7L3B ataxin 7-like 3B
AURKA aurora kinase A
BATF3 basic leucine zipper transcription factor, ATF-like 3
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF10 chromosome 10 open reading frame 10
CES3 carboxylesterase 3
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CNOT4 CCR4-NOT transcription complex, subunit 4
CPT1A carnitine palmitoyltransferase 1A (liver)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLL3 delta-like 3 (Drosophila)
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EGFL7 EGF-like-domain, multiple 7
EHD1 EH-domain containing 1
FABP4 fatty acid binding protein 4, adipocyte
FAM63B family with sequence similarity 63, member B
FBXL7 F-box and leucine-rich repeat protein 7
GLP1R glucagon-like peptide 1 receptor
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HAUS6 HAUS augmin-like complex, subunit 6
HN1L hematological and neurological expressed 1-like
IFI6 interferon, alpha-inducible protein 6
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIF5C kinesin family member 5C
LPIN1 lipin 1
MASP2 mannan-binding lectin serine peptidase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL8 methyltransferase like 8
MIIP migration and invasion inhibitory protein
MNX1 motor neuron and pancreas homeobox 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOP14-AS1 NOP14 antisense RNA 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRCAM neuronal cell adhesion molecule
NUP160 nucleoporin 160kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDS5A PDS5 cohesin associated factor A
PHF3 PHD finger protein 3
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PRKCI protein kinase C, iota
PRPH peripherin
PTCRA pre T-cell antigen receptor alpha
RAB33A RAB33A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RECQL5 RecQ protein-like 5
RNF122 ring finger protein 122
RNF2 ring finger protein 2
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPGRIP1L RPGRIP1-like
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCD5 stearoyl-CoA desaturase 5
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD5 SMAD family member 5
SMYD2 SET and MYND domain containing 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPIN1 spindlin 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TBC1D30 TBC1 domain family, member 30
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TRAF4 TNF receptor-associated factor 4
TRIM14 tripartite motif containing 14
TRIM25 tripartite motif containing 25
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UGT8 UDP glycosyltransferase 8
WNK1 WNK lysine deficient protein kinase 1
WSCD1 WSC domain containing 1
ZBTB6 zinc finger and BTB domain containing 6
ZBTB7A zinc finger and BTB domain containing 7A
ZNF385D zinc finger protein 385D
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAT1 adenosine deaminase, tRNA-specific 1
AGO3 argonaute RISC catalytic component 3
APH1B APH1B gamma secretase subunit
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF7IP2 activating transcription factor 7 interacting protein 2
AXIN1 axin 1
BIRC3 baculoviral IAP repeat containing 3
BOLA1 bolA family member 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CBY1 chibby homolog 1 (Drosophila)
CD83 CD83 molecule
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLCN2 chloride channel, voltage-sensitive 2
CPED1 cadherin-like and PC-esterase domain containing 1
CUL9 cullin 9
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNM1 dynamin 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
ERF Ets2 repressor factor
ETAA1 Ewing tumor-associated antigen 1
FBXL15 F-box and leucine-rich repeat protein 15
FLCN folliculin
FPGS folylpolyglutamate synthase
FSTL3 follistatin-like 3 (secreted glycoprotein)
GATAD2A GATA zinc finger domain containing 2A
GLDC glycine dehydrogenase (decarboxylating)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMIP GEM interacting protein
GRAMD4 GRAM domain containing 4
GSDMD gasdermin D
HIST1H2AE histone cluster 1, H2ae
HIST1H3B histone cluster 1, H3b
HOXC5 homeobox C5
HP1BP3 heterochromatin protein 1, binding protein 3
HS1BP3 HCLS1 binding protein 3
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ISYNA1 inositol-3-phosphate synthase 1
ITPKC inositol-trisphosphate 3-kinase C
KCTD15 potassium channel tetramerization domain containing 15
KIAA0753 KIAA0753
KLHL36 kelch-like family member 36
LRRC61 leucine rich repeat containing 61
MAGEA6 melanoma antigen family A6
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL2 MICAL-like 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTMR12 myotubularin related protein 12
MYL5 myosin, light chain 5, regulatory
NOD1 nucleotide-binding oligomerization domain containing 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUP62CL nucleoporin 62kDa C-terminal like
NUPR1 nuclear protein, transcriptional regulator, 1
ODF2 outer dense fiber of sperm tails 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PDGFRL platelet-derived growth factor receptor-like
PLAC8 placenta-specific 8
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POMT2 protein-O-mannosyltransferase 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRR15L proline rich 15-like
PTGES2 prostaglandin E synthase 2
RAB3A RAB3A, member RAS oncogene family
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPP25 ribonuclease P/MRP 25kDa subunit
SCEL sciellin
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SHPK sedoheptulokinase
SHROOM2 shroom family member 2
SIRT2 sirtuin 2
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TBC1D12 TBC1 domain family, member 12
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TMEM254 transmembrane protein 254
TMEM8B transmembrane protein 8B
TMSB15A thymosin beta 15a
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
USP6 ubiquitin specific peptidase 6
YIPF1 Yip1 domain family, member 1
ZBTB3 zinc finger and BTB domain containing 3
ZNF254 zinc finger protein 254
ZNF767P zinc finger family member 767, pseudogene