tiratricol-2259 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tiratricol-2259 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGO4 argonaute RISC catalytic component 4
AKAP11 A kinase (PRKA) anchor protein 11
ALCAM activated leukocyte cell adhesion molecule
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
APC adenomatous polyposis coli
AQP6 aquaporin 6, kidney specific
ARPIN actin-related protein 2/3 complex inhibitor
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7IP activating transcription factor 7 interacting protein
ATM ATM serine/threonine kinase
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C14ORF79 chromosome 14 open reading frame 79
C3 complement component 3
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCL17 chemokine (C-C motif) ligand 17
CCND2 cyclin D2
CD53 CD53 molecule
CDRT1 CMT1A duplicated region transcript 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTSF cathepsin F
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMC1 DNA meiotic recombinase 1
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNASE2B deoxyribonuclease II beta
DOK4 docking protein 4
DTNB dystrobrevin, beta
DYSF dysferlin
FBXO4 F-box protein 4
FRMPD1 FERM and PDZ domain containing 1
GJA4 gap junction protein, alpha 4, 37kDa
GLB1L galactosidase, beta 1-like
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRM8 glutamate receptor, metabotropic 8
GTDC1 glycosyltransferase-like domain containing 1
HCRP1 hepatocellular carcinoma-related HCRP1
HDC histidine decarboxylase
HOXA1 homeobox A1
HOXB2 homeobox B2
KANK1 KN motif and ankyrin repeat domains 1
KIAA1109 KIAA1109
KLF6 Kruppel-like factor 6
LIMD1 LIM domains containing 1
LINC00260 long intergenic non-protein coding RNA 260
LPAR3 lysophosphatidic acid receptor 3
LRP12 low density lipoprotein receptor-related protein 12
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MPP1 membrane protein, palmitoylated 1, 55kDa
MRC2 mannose receptor, C type 2
MYLK myosin light chain kinase
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEU3 sialidase 3 (membrane sialidase)
NLRP3 NLR family, pyrin domain containing 3
PCDH1 protocadherin 1
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PILRA paired immunoglobin-like type 2 receptor alpha
PIP prolactin-induced protein
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRB1 proline-rich protein BstNI subfamily 1
PRKCI protein kinase C, iota
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTHLH parathyroid hormone-like hormone
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RELN reelin
RHOH ras homolog family member H
RNF126P1 ring finger protein 126 pseudogene 1
SAG S-antigen; retina and pineal gland (arrestin)
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SEZ6L seizure related 6 homolog (mouse)-like
SIRT4 sirtuin 4
SLC16A4 solute carrier family 16, member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNAP25 synaptosomal-associated protein, 25kDa
SNX13 sorting nexin 13
SOX2 SRY (sex determining region Y)-box 2
SRGN serglycin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM63A transmembrane protein 63A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRA T cell receptor alpha locus
ZFP64 ZFP64 zinc finger protein
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARMC4 armadillo repeat containing 4
ATHL1 ATH1, acid trehalase-like 1 (yeast)
AUTS2 autism susceptibility candidate 2
BAHCC1 BAH domain and coiled-coil containing 1
BAHD1 bromo adjacent homology domain containing 1
BATF basic leucine zipper transcription factor, ATF-like
BHLHE41 basic helix-loop-helix family, member e41
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC132 coiled-coil domain containing 132
CCDC9 coiled-coil domain containing 9
CCNT1 cyclin T1
CD80 CD80 molecule
CDHR2 cadherin-related family member 2
CHKB choline kinase beta
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLSPN claspin
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
DBF4B DBF4 zinc finger B
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUSP13 dual specificity phosphatase 13
EVA1B eva-1 homolog B (C. elegans)
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GRAMD1C GRAM domain containing 1C
GRPR gastrin-releasing peptide receptor
GSTCD glutathione S-transferase, C-terminal domain containing
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H4C histone cluster 1, H4c
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
JPH3 junctophilin 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM8 lysine (K)-specific demethylase 8
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LAMP3 lysosomal-associated membrane protein 3
MALL mal, T-cell differentiation protein-like
MAPK10 mitogen-activated protein kinase 10
MBNL3 muscleblind-like splicing regulator 3
MDM4 MDM4, p53 regulator
MEFV Mediterranean fever
METTL16 methyltransferase like 16
MTA2 metastasis associated 1 family, member 2
NLK nemo-like kinase
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
NYNRIN NYN domain and retroviral integrase containing
PACS1 phosphofurin acidic cluster sorting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PLA2G3 phospholipase A2, group III
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRAMEF11 PRAME family member 11
PYHIN1 pyrin and HIN domain family, member 1
RFXAP regulatory factor X-associated protein
RPL10L ribosomal protein L10-like
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRT2 sirtuin 2
SKI SKI proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC46A3 solute carrier family 46, member 3
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNTA1 syntrophin, alpha 1
STMN3 stathmin-like 3
STX1A syntaxin 1A (brain)
TARP TCR gamma alternate reading frame protein
TBKBP1 TBK1 binding protein 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM104 transmembrane protein 104
TMEM209 transmembrane protein 209
TMLHE trimethyllysine hydroxylase, epsilon
WBP2 WW domain binding protein 2
WDR91 WD repeat domain 91
YY2 YY2 transcription factor
ZNF350 zinc finger protein 350
ZNF37BP zinc finger protein 37B, pseudogene
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862