tnfrsf11a Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	tumor necrosis factor receptor superfamily, member 11a, NFKB activator\|The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012] (NCBI Entrez Gene Database, 8792)
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Genes

10 genes co-occuring with the biological term tnfrsf11a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
CLCN7	chloride channel, voltage-sensitive 7
CSF1	colony stimulating factor 1 (macrophage)
DCSTAMP	dendrocyte expressed seven transmembrane protein
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
OPTN	optineurin
OSTM1	osteopetrosis associated transmembrane protein 1
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11