| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tobramycin-2481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ADORA1 | adenosine A1 receptor |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10A | ATPase, class V, type 10A |
| ATP13A2 | ATPase type 13A2 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CA12 | carbonic anhydrase XII |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCKAR | cholecystokinin A receptor |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CEP164 | centrosomal protein 164kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| COL9A3 | collagen, type IX, alpha 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DLX2 | distal-less homeobox 2 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| ELAC1 | elaC ribonuclease Z 1 |
| EPHB2 | EPH receptor B2 |
| FAM155A | family with sequence similarity 155, member A |
| FAM65B | family with sequence similarity 65, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GATA2 | GATA binding protein 2 |
| GCH1 | GTP cyclohydrolase 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GPC1 | glypican 1 |
| GPR3 | G protein-coupled receptor 3 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HOXA3 | homeobox A3 |
| HOXB5 | homeobox B5 |
| HPR | haptoglobin-related protein |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| IQCK | IQ motif containing K |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KSR1 | kinase suppressor of ras 1 |
| LAMA4 | laminin, alpha 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIMK1 | LIM domain kinase 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MEF2C | myocyte enhancer factor 2C |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPZL1 | myelin protein zero-like 1 |
| NF2 | neurofibromin 2 (merlin) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NUP88 | nucleoporin 88kDa |
| NXF2 | nuclear RNA export factor 2 |
| OLFM1 | olfactomedin 1 |
| OPTN | optineurin |
| OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| PDE8B | phosphodiesterase 8B |
| PIP | prolactin-induced protein |
| PLAT | plasminogen activator, tissue |
| PMP22 | peripheral myelin protein 22 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PTGES | prostaglandin E synthase |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PYGB | phosphorylase, glycogen; brain |
| RAB11B | RAB11B, member RAS oncogene family |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB3D | RAB3D, member RAS oncogene family |
| RGS4 | regulator of G-protein signaling 4 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SETBP1 | SET binding protein 1 |
| SLAMF7 | SLAM family member 7 |
| SPATA1 | spermatogenesis associated 1 |
| SSTR2 | somatostatin receptor 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TGFB1 | transforming growth factor, beta 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRBC1 | T cell receptor beta constant 1 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABHD17B | abhydrolase domain containing 17B |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BNC2 | basonuclin 2 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CD300C | CD300c molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CENPJ | centromere protein J |
| CFP | complement factor properdin |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLEC2D | C-type lectin domain family 2, member D |
| CRY2 | cryptochrome circadian clock 2 |
| CXORF56 | chromosome X open reading frame 56 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| EFNA3 | ephrin-A3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| FAM102A | family with sequence similarity 102, member A |
| FEM1C | fem-1 homolog c (C. elegans) |
| FGL2 | fibrinogen-like 2 |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| G0S2 | G0/G1 switch 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD1B | GRAM domain containing 1B |
| GTF2I | general transcription factor IIi |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INCENP | inner centromere protein antigens 135/155kDa |
| IQCG | IQ motif containing G |
| IREB2 | iron-responsive element binding protein 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA1107 | KIAA1107 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL12 | kelch-like family member 12 |
| KLHL28 | kelch-like family member 28 |
| LMAN1 | lectin, mannose-binding, 1 |
| LTC4S | leukotriene C4 synthase |
| MED9 | mediator complex subunit 9 |
| MEGF8 | multiple EGF-like-domains 8 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| NCS1 | neuronal calcium sensor 1 |
| NLK | nemo-like kinase |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRBP1 | nuclear receptor binding protein 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUBPL | nucleotide binding protein-like |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PADI2 | peptidyl arginine deiminase, type II |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| POLM | polymerase (DNA directed), mu |
| POM121 | POM121 transmembrane nucleoporin |
| PROCR | protein C receptor, endothelial |
| PRR4 | proline rich 4 (lacrimal) |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK4 | serine/threonine kinase 4 |
| TBC1D19 | TBC1 domain family, member 19 |
| TCTN2 | tectonic family member 2 |
| TRIM25 | tripartite motif containing 25 |
| TSPYL2 | TSPY-like 2 |
| TWISTNB | TWIST neighbor |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF155 | zinc finger protein 155 |
| ZNF225 | zinc finger protein 225 |
| ZNF345 | zinc finger protein 345 |
| ZNF528 | zinc finger protein 528 |
| ZNF552 | zinc finger protein 552 |
