tobramycin-2841 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the tobramycin-2841 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACVR1B activin A receptor, type IB
ADORA3 adenosine A3 receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALCAM activated leukocyte cell adhesion molecule
APLP1 amyloid beta (A4) precursor-like protein 1
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C11ORF63 chromosome 11 open reading frame 63
CA12 carbonic anhydrase XII
CAPN5 calpain 5
CAPN9 calpain 9
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC132 coiled-coil domain containing 132
CD83 CD83 molecule
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELF2 CUGBP, Elav-like family member 2
COL1A1 collagen, type I, alpha 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
DIO2 deiodinase, iodothyronine, type II
DMRT1 doublesex and mab-3 related transcription factor 1
DOCK9 dedicator of cytokinesis 9
DOPEY2 dopey family member 2
ELSPBP1 epididymal sperm binding protein 1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM182B family with sequence similarity 182, member B
FGFR1 fibroblast growth factor receptor 1
FOXN3 forkhead box N3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPSM3 G-protein signaling modulator 3
GRM1 glutamate receptor, metabotropic 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAO2 hydroxyacid oxidase 2 (long chain)
HDAC7 histone deacetylase 7
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXC10 homeobox C10
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA10 integrin, alpha 10
LMO2 LIM domain only 2 (rhombotin-like 1)
LZTR1 leucine-zipper-like transcription regulator 1
MAX MYC associated factor X
METTL7A methyltransferase like 7A
MNMIP1 manchette microtubule inner protein 1
NACAD NAC alpha domain containing
NCAPH2 non-SMC condensin II complex, subunit H2
NME5 NME/NM23 family member 5
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OSBPL10 oxysterol binding protein-like 10
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PDE9A phosphodiesterase 9A
PDLIM7 PDZ and LIM domain 7 (enigma)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLCD1 phospholipase C, delta 1
PLCH1 phospholipase C, eta 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTH2R parathyroid hormone 2 receptor
RGS14 regulator of G-protein signaling 14
RNF122 ring finger protein 122
RYR1 ryanodine receptor 1 (skeletal)
SH3BP2 SH3-domain binding protein 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC22A14 solute carrier family 22, member 14
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC39A9 solute carrier family 39, member 9
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMC4 structural maintenance of chromosomes 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRPX2 sushi-repeat containing protein, X-linked 2
STARD8 StAR-related lipid transfer (START) domain containing 8
SUGP1 SURP and G patch domain containing 1
SYN2 synapsin II
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TGM2 transglutaminase 2
TK2 thymidine kinase 2, mitochondrial
TM6SF1 transmembrane 6 superfamily member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAM1 translocation associated membrane protein 1
UBQLN4 ubiquilin 4
USP12 ubiquitin specific peptidase 12
USP27X ubiquitin specific peptidase 27, X-linked
VAV2 vav 2 guanine nucleotide exchange factor
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEGFA vascular endothelial growth factor A
ZCCHC14 zinc finger, CCHC domain containing 14
ZFHX4 zinc finger homeobox 4
ZNF137P zinc finger protein 137, pseudogene
ZNF37BP zinc finger protein 37B, pseudogene
ZNF446 zinc finger protein 446
ZSCAN31 zinc finger and SCAN domain containing 31

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
AHR aryl hydrocarbon receptor
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG4A autophagy related 4A, cysteine peptidase
BCOR BCL6 corepressor
BFSP1 beaded filament structural protein 1, filensin
BGLAP bone gamma-carboxyglutamate (gla) protein
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEC cell death-inducing DFFA-like effector c
CLASRP CLK4-associating serine/arginine rich protein
CLDN15 claudin 15
COBL cordon-bleu WH2 repeat protein
COQ6 coenzyme Q6 monooxygenase
CORO1A coronin, actin binding protein, 1A
CORT cortistatin
CPTP ceramide-1-phosphate transfer protein
CRABP1 cellular retinoic acid binding protein 1
CTAGE9 CTAGE family, member 9
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND4A DENN/MADD domain containing 4A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERBB2IP erbb2 interacting protein
ERCC5 excision repair cross-complementation group 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F8 coagulation factor VIII, procoagulant component
FAM46C family with sequence similarity 46, member C
FKBP10 FK506 binding protein 10, 65 kDa
GK3P glycerol kinase 3 pseudogene
HIST1H2AI histone cluster 1, H2ai
HIST1H4D histone cluster 1, H4d
HMOX1 heme oxygenase 1
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HYI hydroxypyruvate isomerase (putative)
ICK intestinal cell (MAK-like) kinase
IPO8 importin 8
KIAA0894 KIAA0894 protein
KIAA0895 KIAA0895
KIF16B kinesin family member 16B
KIZ kizuna centrosomal protein
KLHL36 kelch-like family member 36
LRRC37A2 leucine rich repeat containing 37, member A2
MAGOHB mago-nashi homolog B (Drosophila)
MAST3 microtubule associated serine/threonine kinase 3
MEX3C mex-3 RNA binding family member C
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPAL2 NIPA-like domain containing 2
NR1H2 nuclear receptor subfamily 1, group H, member 2
NRBF2 nuclear receptor binding factor 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
P3H1 prolyl 3-hydroxylase 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITX2 paired-like homeodomain 2
POLH polymerase (DNA directed), eta
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SLC12A8 solute carrier family 12, member 8
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLMO2 slowmo homolog 2 (Drosophila)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SYNGR3 synaptogyrin 3
SYT17 synaptotagmin XVII
TBX19 T-box 19
TLN1 talin 1
TMEM115 transmembrane protein 115
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TMEM62 transmembrane protein 62
TRIM5 tripartite motif containing 5
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TWF2 twinfilin actin binding protein 2
USP20 ubiquitin specific peptidase 20
VEGFC vascular endothelial growth factor C
WWC2 WW and C2 domain containing 2
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF107 zinc finger protein 107
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNF329 zinc finger protein 329
ZNF516 zinc finger protein 516
ZNF574 zinc finger protein 574
ZNF675 zinc finger protein 675
ZNF767P zinc finger family member 767, pseudogene