tocainide-2931 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tocainide-2931 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ANGPTL2 angiopoietin-like 2
ANKRD6 ankyrin repeat domain 6
ATG10 autophagy related 10
B3GNT1
C9ORF3 chromosome 9 open reading frame 3
CAPN15 calpain 15
CAPZB capping protein (actin filament) muscle Z-line, beta
CC2D1A coiled-coil and C2 domain containing 1A
CD79A CD79a molecule, immunoglobulin-associated alpha
CDCP1 CUB domain containing protein 1
CECR1 cat eye syndrome chromosome region, candidate 1
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CLCF1 cardiotrophin-like cytokine factor 1
CLCN7 chloride channel, voltage-sensitive 7
COL10A1 collagen, type X, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CRHR1 corticotropin releasing hormone receptor 1
CROT carnitine O-octanoyltransferase
CTNND1 catenin (cadherin-associated protein), delta 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DHRS12 dehydrogenase/reductase (SDR family) member 12
EFNA5 ephrin-A5
EHD1 EH-domain containing 1
FAM102A family with sequence similarity 102, member A
FAS Fas cell surface death receptor
FOSL2 FOS-like antigen 2
FUT2 fucosyltransferase 2 (secretor status included)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAL galanin/GMAP prepropeptide
GPR107 G protein-coupled receptor 107
GPR20 G protein-coupled receptor 20
GRM7 glutamate receptor, metabotropic 7
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HOXB9 homeobox B9
ICA1 islet cell autoantigen 1, 69kDa
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFNA16 interferon, alpha 16
KAT8 K(lysine) acetyltransferase 8
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KHSRP KH-type splicing regulatory protein
LAMB4 laminin, beta 4
LRRC41 leucine rich repeat containing 41
MAX MYC associated factor X
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MCAM melanoma cell adhesion molecule
MED31 mediator complex subunit 31
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MYOZ1 myozenin 1
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPTX2 neuronal pentraxin II
OSGIN2 oxidative stress induced growth inhibitor family member 2
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PACS1 phosphofurin acidic cluster sorting protein 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHF1 PHD finger protein 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB40A RAB40A, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RRBP1 ribosome binding protein 1
S100A8 S100 calcium binding protein A8
SCIN scinderin
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD1A SET domain containing 1A
SIGLEC7 sialic acid binding Ig-like lectin 7
SIRT6 sirtuin 6
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SPATA20 spermatogenesis associated 20
SPHK1 sphingosine kinase 1
SRRM2 serine/arginine repetitive matrix 2
STX2 syntaxin 2
SUN1 Sad1 and UNC84 domain containing 1
TAOK2 TAO kinase 2
TAS2R1 taste receptor, type 2, member 1
TAZ tafazzin
TBX6 T-box 6
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TIMELESS timeless circadian clock
TK2 thymidine kinase 2, mitochondrial
TLN2 talin 2
TNS1 tensin 1
TRIM62 tripartite motif containing 62
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSPAN9 tetraspanin 9
TUBA3C tubulin, alpha 3c
TYMP thymidine phosphorylase
ZBTB7A zinc finger and BTB domain containing 7A
ZER1 zyg-11 related, cell cycle regulator
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF202 zinc finger protein 202
ZNF235 zinc finger protein 235
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
AEN apoptosis enhancing nuclease
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASB7 ankyrin repeat and SOCS box containing 7
ASPN asporin
BIRC3 baculoviral IAP repeat containing 3
BPI bactericidal/permeability-increasing protein
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C17ORF53 chromosome 17 open reading frame 53
C19ORF24 chromosome 19 open reading frame 24
C7ORF43 chromosome 7 open reading frame 43
CCDC186 coiled-coil domain containing 186
CD101 CD101 molecule
CD180 CD180 molecule
CDK6 cyclin-dependent kinase 6
CHMP6 charged multivesicular body protein 6
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CPTP ceramide-1-phosphate transfer protein
CSF1R colony stimulating factor 1 receptor
CYSLTR1 cysteinyl leukotriene receptor 1
DCAF13 DDB1 and CUL4 associated factor 13
DENND5B DENN/MADD domain containing 5B
DFNA5 deafness, autosomal dominant 5
DGKG diacylglycerol kinase, gamma 90kDa
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EGR2 early growth response 2
FAM127B family with sequence similarity 127, member B
FGF9 fibroblast growth factor 9
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1T histone cluster 1, H1t
HIST1H2AI histone cluster 1, H2ai
HIST2H2AA3 histone cluster 2, H2aa3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLF7 Kruppel-like factor 7 (ubiquitous)
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPTN kaptin (actin binding protein)
LINC00115 long intergenic non-protein coding RNA 115
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LNPEP leucyl/cystinyl aminopeptidase
LOC729164 hCG1732469
MAGEB2 melanoma antigen family B2
MAGEF1 melanoma antigen family F1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MATK megakaryocyte-associated tyrosine kinase
MCMBP minichromosome maintenance complex binding protein
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MKL2 MKL/myocardin-like 2
MLYCD malonyl-CoA decarboxylase
MTERF4 mitochondrial transcription termination factor 4
MVD mevalonate (diphospho) decarboxylase
MYBPH myosin binding protein H
NOL10 nucleolar protein 10
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PAQR4 progestin and adipoQ receptor family member IV
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDLIM1 PDZ and LIM domain 1
PTH2R parathyroid hormone 2 receptor
PYGB phosphorylase, glycogen; brain
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
SGMS1 sphingomyelin synthase 1
SLAMF7 SLAM family member 7
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC35F6 solute carrier family 35, member F6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNHG20 small nucleolar RNA host gene 20
SP1 Sp1 transcription factor
SPAG4 sperm associated antigen 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
STX1A syntaxin 1A (brain)
SYCP2 synaptonemal complex protein 2
TBXAS1 thromboxane A synthase 1 (platelet)
TCTN1 tectonic family member 1
TESK1 testis-specific kinase 1
THEM6 thioesterase superfamily member 6
TLR6 toll-like receptor 6
TMEM242 transmembrane protein 242
TSC22D4 TSC22 domain family, member 4
TSPAN32 tetraspanin 32
TUBA3D tubulin, alpha 3d
VNN1 vanin 1
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZC4H2 zinc finger, C4H2 domain containing
ZNF10 zinc finger protein 10
ZNF250 zinc finger protein 250
ZNF428 zinc finger protein 428
ZNF701 zinc finger protein 701
ZNF770 zinc finger protein 770