| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the tocainide-4256 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTN2 | actinin, alpha 2 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APOE | apolipoprotein E |
| ASTN2 | astrotactin 2 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| ATXN3L | ataxin 3-like |
| ATXN7L1 | ataxin 7-like 1 |
| B9D1 | B9 protein domain 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CCDC134 | coiled-coil domain containing 134 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLIC5 | chloride intracellular channel 5 |
| CNTNAP2 | contactin associated protein-like 2 |
| CORO1B | coronin, actin binding protein, 1B |
| CTIF | CBP80/20-dependent translation initiation factor |
| DKFZP434L187 | uncharacterized LOC26082 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DRD2 | dopamine receptor D2 |
| DSG3 | desmoglein 3 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EDNRA | endothelin receptor type A |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FAS | Fas cell surface death receptor |
| FMO3 | flavin containing monooxygenase 3 |
| GAS7 | growth arrest-specific 7 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GIMAP6 | GTPase, IMAP family member 6 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HFE | hemochromatosis |
| IDS | iduronate 2-sulfatase |
| IGHM | immunoglobulin heavy constant mu |
| IGSF6 | immunoglobulin superfamily, member 6 |
| INO80D | INO80 complex subunit D |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM5B | lysine (K)-specific demethylase 5B |
| KDR | kinase insert domain receptor |
| LAG3 | lymphocyte-activation gene 3 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP3 | matrix metallopeptidase 3 |
| MST1 | macrophage stimulating 1 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NME5 | NME/NM23 family member 5 |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NRTN | neurturin |
| ORC5 | origin recognition complex, subunit 5 |
| OSBPL7 | oxysterol binding protein-like 7 |
| PAPOLG | poly(A) polymerase gamma |
| PAPPA2 | pappalysin 2 |
| PAX5 | paired box 5 |
| PCDH11Y | protocadherin 11 Y-linked |
| PDCD6 | programmed cell death 6 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PML | promyelocytic leukemia |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRDM14 | PR domain containing 14 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RBFA | ribosome binding factor A (putative) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RET | ret proto-oncogene |
| RGS5 | regulator of G-protein signaling 5 |
| RHEB | Ras homolog enriched in brain |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| RUNX1 | runt-related transcription factor 1 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SPRYD7 | SPRY domain containing 7 |
| SRPK3 | SRSF protein kinase 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| TBXA2R | thromboxane A2 receptor |
| TDRKH | tudor and KH domain containing |
| TEX13A | testis expressed 13A |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TUBA3C | tubulin, alpha 3c |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| YIPF4 | Yip1 domain family, member 4 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZNF155 | zinc finger protein 155 |
| ZNF219 | zinc finger protein 219 |
| ZNF391 | zinc finger protein 391 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ANGPT4 | angiopoietin 4 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CA9 | carbonic anhydrase IX |
| CABP2 | calcium binding protein 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC186 | coiled-coil domain containing 186 |
| CCNO | cyclin O |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CELP | carboxyl ester lipase pseudogene |
| CES3 | carboxylesterase 3 |
| CLEC10A | C-type lectin domain family 10, member A |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNN1 | calponin 1, basic, smooth muscle |
| COMP | cartilage oligomeric matrix protein |
| CRLF1 | cytokine receptor-like factor 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DBF4B | DBF4 zinc finger B |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| ERCC4 | excision repair cross-complementation group 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FA2H | fatty acid 2-hydroxylase |
| FAM13C | family with sequence similarity 13, member C |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO40 | F-box protein 40 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRM4 | glutamate receptor, metabotropic 4 |
| HAL | histidine ammonia-lyase |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4E | histone cluster 1, H4e |
| HPR | haptoglobin-related protein |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL17RB | interleukin 17 receptor B |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIF13A | kinesin family member 13A |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC257152 | uncharacterized LOC257152 |
| LOC729164 | hCG1732469 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAK | male germ cell-associated kinase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MGP | matrix Gla protein |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3A | mucin 3A, cell surface associated |
| MYOZ3 | myozenin 3 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OLFML2B | olfactomedin-like 2B |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| PALM | paralemmin |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCDH12 | protocadherin 12 |
| PGM5 | phosphoglucomutase 5 |
| PLAC8 | placenta-specific 8 |
| PLBD1 | phospholipase B domain containing 1 |
| PMP2 | peripheral myelin protein 2 |
| POU6F2 | POU class 6 homeobox 2 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPL | periplakin |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRM2 | protamine 2 |
| PROL1 | proline rich, lacrimal 1 |
| PRSS50 | protease, serine, 50 |
| PRSS53 | protease, serine, 53 |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| RNF122 | ring finger protein 122 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SSBP3 | single stranded DNA binding protein 3 |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TCP11 | t-complex 11, testis-specific |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TLR4 | toll-like receptor 4 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF510 | zinc finger protein 510 |
| ZNF76 | zinc finger protein 76 |
