tocainide-4838 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

195 genes differentially expressed following the tocainide-4838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AKAP8L A kinase (PRKA) anchor protein 8-like
AQP3 aquaporin 3 (Gill blood group)
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
CBX8 chromobox homolog 8
CC2D1A coiled-coil and C2 domain containing 1A
CCNG2 cyclin G2
CRY2 cryptochrome circadian clock 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
DCAF11 DDB1 and CUL4 associated factor 11
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR8 DGCR8 microprocessor complex subunit
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DPF1 D4, zinc and double PHD fingers family 1
EHD2 EH-domain containing 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EVPL envoplakin
FAM212B family with sequence similarity 212, member B
FBLN1 fibulin 1
FBXL8 F-box and leucine-rich repeat protein 8
FKBP8 FK506 binding protein 8, 38kDa
FLII flightless I homolog (Drosophila)
FSCN1 fascin actin-bundling protein 1
GADD45B growth arrest and DNA-damage-inducible, beta
GFI1 growth factor independent 1 transcription repressor
GJB3 gap junction protein, beta 3, 31kDa
HDAC5 histone deacetylase 5
HOXA4 homeobox A4
ICOSLG inducible T-cell co-stimulator ligand
IFI6 interferon, alpha-inducible protein 6
IFT27 intraflagellar transport 27
IL17RA interleukin 17 receptor A
ILF3 interleukin enhancer binding factor 3, 90kDa
INADL InaD-like (Drosophila)
ITGB4 integrin, beta 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KHK ketohexokinase (fructokinase)
KIAA0319L KIAA0319-like
KIDINS220 kinase D-interacting substrate, 220kDa
KLF4 Kruppel-like factor 4 (gut)
KLHL22 kelch-like family member 22
LIG3 ligase III, DNA, ATP-dependent
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MUC5B mucin 5B, oligomeric mucus/gel-forming
NABP2 nucleic acid binding protein 2
NFYA nuclear transcription factor Y, alpha
NMT1 N-myristoyltransferase 1
NOTCH2 notch 2
NPTX1 neuronal pentraxin I
PACS2 phosphofurin acidic cluster sorting protein 2
PCDHB13 protocadherin beta 13
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PISD phosphatidylserine decarboxylase
POMT2 protein-O-mannosyltransferase 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKCH protein kinase C, eta
PRKX protein kinase, X-linked
PRPF31 pre-mRNA processing factor 31
PTBP3 polypyrimidine tract binding protein 3
QKI QKI, KH domain containing, RNA binding
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RANGAP1 Ran GTPase activating protein 1
RHOBTB2 Rho-related BTB domain containing 2
RIMS3 regulating synaptic membrane exocytosis 3
RPS14 ribosomal protein S14
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SIRT5 sirtuin 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SPEG SPEG complex locus
SQLE squalene epoxidase
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF3 transcription factor 3
TCP11L1 t-complex 11, testis-specific-like 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOP3B topoisomerase (DNA) III beta
TOX4 TOX high mobility group box family member 4
TP53I11 tumor protein p53 inducible protein 11
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TXNRD2 thioredoxin reductase 2
ULBP2 UL16 binding protein 2
WDR55 WD repeat domain 55
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WWOX WW domain containing oxidoreductase
ZER1 zyg-11 related, cell cycle regulator
ZNF337 zinc finger protein 337
ZNF592 zinc finger protein 592
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ALPK1 alpha-kinase 1
AMT aminomethyltransferase
ATAT1 alpha tubulin acetyltransferase 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHCC1 BAH domain and coiled-coil containing 1
C10ORF95 chromosome 10 open reading frame 95
C2 complement component 2
C2ORF27A chromosome 2 open reading frame 27A
CD53 CD53 molecule
CENPO centromere protein O
CNR2 cannabinoid receptor 2 (macrophage)
CPED1 cadherin-like and PC-esterase domain containing 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDAR ectodysplasin A receptor
EML4 echinoderm microtubule associated protein like 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXL7 F-box and leucine-rich repeat protein 7
FCHSD2 FCH and double SH3 domains 2
FLJ21369 uncharacterized protein FLJ21369
GADD45G growth arrest and DNA-damage-inducible, gamma
GLTSCR1 glioma tumor suppressor candidate region gene 1
GMPR guanosine monophosphate reductase
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HHAT hedgehog acyltransferase
HIST1H2AK histone cluster 1, H2ak
HYAL3 hyaluronoglucosaminidase 3
IDI2-AS1 IDI2 antisense RNA 1
IL2 interleukin 2
INO80D INO80 complex subunit D
IPO8 importin 8
KCTD7 potassium channel tetramerization domain containing 7
KIAA0754 KIAA0754
LARP6 La ribonucleoprotein domain family, member 6
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP2 low density lipoprotein receptor-related protein 2
MED15 mediator complex subunit 15
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
MYO1F myosin IF
NCALD neurocalcin delta
NIPAL2 NIPA-like domain containing 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PMCH pro-melanin-concentrating hormone
PRF1 perforin 1 (pore forming protein)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB3A RAB3A, member RAS oncogene family
RCAN3 RCAN family member 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCGB2A2 secretoglobin, family 2A, member 2
SCHIP1 schwannomin interacting protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SECTM1 secreted and transmembrane 1
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
TICAM1 toll-like receptor adaptor molecule 1
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN5 tetraspanin 5
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
VEGFC vascular endothelial growth factor C
XYLT1 xylosyltransferase I
ZNF446 zinc finger protein 446
ZNF623 zinc finger protein 623
ZNF669 zinc finger protein 669
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747