| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tocainide-7351 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AGXT | alanine-glyoxylate aminotransferase |
| AHI1 | Abelson helper integration site 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARTN | artemin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP11A | ATPase, class VI, type 11A |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BIN1 | bridging integrator 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC88A | coiled-coil domain containing 88A |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CHKB | choline kinase beta |
| CHM | choroideremia (Rab escort protein 1) |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CXORF21 | chromosome X open reading frame 21 |
| DALRD3 | DALR anticodon binding domain containing 3 |
| ELL2 | elongation factor, RNA polymerase II, 2 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM214B | family with sequence similarity 214, member B |
| FLJ11292 | |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GM2A | GM2 ganglioside activator |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HFE | hemochromatosis |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXA6 | homeobox A6 |
| HOXB1 | homeobox B1 |
| KIAA0368 | KIAA0368 |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KIZ | kizuna centrosomal protein |
| KLHL22 | kelch-like family member 22 |
| LMAN1 | lectin, mannose-binding, 1 |
| LMF2 | lipase maturation factor 2 |
| MAP1A | microtubule-associated protein 1A |
| METTL7A | methyltransferase like 7A |
| MFAP3L | microfibrillar-associated protein 3-like |
| MMRN2 | multimerin 2 |
| N4BP3 | NEDD4 binding protein 3 |
| NAG18 | NAG18 mRNA |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NEUROD4 | neuronal differentiation 4 |
| NFRKB | nuclear factor related to kappaB binding protein |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCDHB17P | protocadherin beta 17 pseudogene |
| PDAP1 | PDGFA associated protein 1 |
| PDE8B | phosphodiesterase 8B |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHF3 | PHD finger protein 3 |
| PICK1 | protein interacting with PRKCA 1 |
| PVR | poliovirus receptor |
| PXN | paxillin |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB11B | RAB11B, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RANBP1 | RAN binding protein 1 |
| RBM19 | RNA binding motif protein 19 |
| RECQL5 | RecQ protein-like 5 |
| REST | RE1-silencing transcription factor |
| RGS12 | regulator of G-protein signaling 12 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| RPLP2 | ribosomal protein, large, P2 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| S100A8 | S100 calcium binding protein A8 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SSPN | sarcospan |
| STMN1 | stathmin 1 |
| STON1 | stonin 1 |
| TBX6 | T-box 6 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TPMT | thiopurine S-methyltransferase |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM3 | tripartite motif containing 3 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| XDH | xanthine dehydrogenase |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZNF682 | zinc finger protein 682 |
| ZNF778 | zinc finger protein 778 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| AIM1 | absent in melanoma 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATG2A | autophagy related 2A |
| BAG4 | BCL2-associated athanogene 4 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C5 | complement component 5 |
| CCDC69 | coiled-coil domain containing 69 |
| CDK3 | cyclin-dependent kinase 3 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| COQ6 | coenzyme Q6 monooxygenase |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DNMBP | dynamin binding protein |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAAH | fatty acid amide hydrolase |
| FAM53B | family with sequence similarity 53, member B |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOSL1 | FOS-like antigen 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPC3 | glypican 3 |
| GPX2 | glutathione peroxidase 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HMOX1 | heme oxygenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL4R | interleukin 4 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF1 | interferon regulatory factor 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0125 | KIAA0125 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMNB1 | lamin B1 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NBEAL2 | neurobeachin-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NRSN2 | neurensin 2 |
| PCDHA6 | protocadherin alpha 6 |
| PCDHB3 | protocadherin beta 3 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RBL1 | retinoblastoma-like 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF31 | ring finger protein 31 |
| RNF39 | ring finger protein 39 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2D4A | SH2 domain containing 4A |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TDRD1 | tudor domain containing 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| ULBP2 | UL16 binding protein 2 |
| VWA9 | von Willebrand factor A domain containing 9 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF141 | zinc finger protein 141 |
| ZNF212 | zinc finger protein 212 |
| ZNF480 | zinc finger protein 480 |
| ZNF574 | zinc finger protein 574 |
| ZNF623 | zinc finger protein 623 |
| ZNF747 | zinc finger protein 747 |
