| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the todralazine-1677 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD3 | adducin 3 (gamma) |
| ADM | adrenomedullin |
| AGFG1 | ArfGAP with FG repeats 1 |
| AK2 | adenylate kinase 2 |
| ALPK1 | alpha-kinase 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| ATF6B | activating transcription factor 6 beta |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CD48 | CD48 molecule |
| CD83 | CD83 molecule |
| CHST10 | carbohydrate sulfotransferase 10 |
| CUL7 | cullin 7 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| EMC1 | ER membrane protein complex subunit 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERCC2 | excision repair cross-complementation group 2 |
| FBXO31 | F-box protein 31 |
| FMOD | fibromodulin |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSPT1 | G1 to S phase transition 1 |
| HAP1 | huntingtin-associated protein 1 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HN1L | hematological and neurological expressed 1-like |
| IGHM | immunoglobulin heavy constant mu |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL1B | interleukin 1, beta |
| IRS2 | insulin receptor substrate 2 |
| ITGB5 | integrin, beta 5 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KIAA0125 | KIAA0125 |
| KLHDC8A | kelch domain containing 8A |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCOLN3 | mucolipin 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTF2 | metal response element binding transcription factor 2 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NKX3-1 | NK3 homeobox 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PARVA | parvin, alpha |
| PDE10A | phosphodiesterase 10A |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLA2G10 | phospholipase A2, group X |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLK4 | polo-like kinase 4 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB28 | RAB28, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RANBP3 | RAN binding protein 3 |
| RCAN1 | regulator of calcineurin 1 |
| REEP1 | receptor accessory protein 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIK3 | SIK family kinase 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SIRT3 | sirtuin 3 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SNTA1 | syntrophin, alpha 1 |
| SNW1 | SNW domain containing 1 |
| SYNJ1 | synaptojanin 1 |
| SYNJ2 | synaptojanin 2 |
| TAGLN | transgelin |
| TBC1D19 | TBC1 domain family, member 19 |
| TBC1D5 | TBC1 domain family, member 5 |
| TGM2 | transglutaminase 2 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS4 | transmembrane protease, serine 4 |
| TRIM29 | tripartite motif containing 29 |
| TSPAN9 | tetraspanin 9 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDR33 | WD repeat domain 33 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF350 | zinc finger protein 350 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATXN2 | ataxin 2 |
| AXIN1 | axin 1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CARD8 | caspase recruitment domain family, member 8 |
| CCNE1 | cyclin E1 |
| CCNT1 | cyclin T1 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP72 | centrosomal protein 72kDa |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 |
| COPS7B | COP9 signalosome subunit 7B |
| CTNNBL1 | catenin, beta like 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DOCK1 | dedicator of cytokinesis 1 |
| DSE | dermatan sulfate epimerase |
| DUSP5 | dual specificity phosphatase 5 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM155B | family with sequence similarity 155, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FHOD1 | formin homology 2 domain containing 1 |
| FLJ22184 | |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAA | glucosidase, alpha; acid |
| GLTP | glycolipid transfer protein |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HOXC13 | homeobox C13 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KLC2 | kinesin light chain 2 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAP1S | microtubule-associated protein 1S |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MOSPD3 | motile sperm domain containing 3 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NEK11 | NIMA-related kinase 11 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| OTUD3 | OTU deubiquitinase 3 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PISD | phosphatidylserine decarboxylase |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBM42 | RNA binding motif protein 42 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RNF31 | ring finger protein 31 |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A4 | S100 calcium binding protein A4 |
| SH2D4A | SH2 domain containing 4A |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| TBCC | tubulin folding cofactor C |
| TESK2 | testis-specific kinase 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM120B | transmembrane protein 120B |
| TMEM184C | transmembrane protein 184C |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIM25 | tripartite motif containing 25 |
| USP18 | ubiquitin specific peptidase 18 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF140 | zinc finger protein 140 |
| ZNF250 | zinc finger protein 250 |
| ZNF282 | zinc finger protein 282 |
| ZNF408 | zinc finger protein 408 |
| ZNF573 | zinc finger protein 573 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
