| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the todralazine-1799 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ACTN2 | actinin, alpha 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANKRD12 | ankyrin repeat domain 12 |
| AP3S2 | adaptor-related protein complex 3, sigma 2 subunit |
| APP | amyloid beta (A4) precursor protein |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| BCL6 | B-cell CLL/lymphoma 6 |
| BLVRA | biliverdin reductase A |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYHR1 | cysteine/histidine-rich 1 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| E2F5 | E2F transcription factor 5, p130-binding |
| ECE1 | endothelin converting enzyme 1 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM175B | family with sequence similarity 175, member B |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FDX1 | ferredoxin 1 |
| FMO4 | flavin containing monooxygenase 4 |
| FOLR1 | folate receptor 1 (adult) |
| FSCN1 | fascin actin-bundling protein 1 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GOSR1 | golgi SNAP receptor complex member 1 |
| GPR137 | G protein-coupled receptor 137 |
| GPR19 | G protein-coupled receptor 19 |
| GPR3 | G protein-coupled receptor 3 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HDAC6 | histone deacetylase 6 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGA10 | integrin, alpha 10 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KDM4A | lysine (K)-specific demethylase 4A |
| KIF13B | kinesin family member 13B |
| MED28 | mediator complex subunit 28 |
| MIS18BP1 | MIS18 binding protein 1 |
| MTAP | methylthioadenosine phosphorylase |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFYA | nuclear transcription factor Y, alpha |
| NINL | ninein-like |
| NPEPL1 | aminopeptidase-like 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PAPOLA | poly(A) polymerase alpha |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHTF1 | putative homeodomain transcription factor 1 |
| PRNP | prion protein |
| RARS | arginyl-tRNA synthetase |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RDX | radixin |
| RHOT2 | ras homolog family member T2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SAR1A | secretion associated, Ras related GTPase 1A |
| SCARB2 | scavenger receptor class B, member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SGSM2 | small G protein signaling modulator 2 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SMC1A | structural maintenance of chromosomes 1A |
| SSH3 | slingshot protein phosphatase 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK17B | serine/threonine kinase 17b |
| TAZ | tafazzin |
| TBXA2R | thromboxane A2 receptor |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TOR1AIP1 | torsin A interacting protein 1 |
| TRIM29 | tripartite motif containing 29 |
| TTC38 | tetratricopeptide repeat domain 38 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| UTRN | utrophin |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| WDR91 | WD repeat domain 91 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF224 | zinc finger protein 224 |
| ZNF500 | zinc finger protein 500 |
| ZNF84 | zinc finger protein 84 |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAX | BCL2-associated X protein |
| BBS7 | Bardet-Biedl syndrome 7 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNJL | cyclin J-like |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CLSPN | claspin |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYB5R4 | cytochrome b5 reductase 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EDN1 | endothelin 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FUZ | fuzzy planar cell polarity protein |
| GID4 | GID complex subunit 4 |
| GMIP | GEM interacting protein |
| GPR1 | G protein-coupled receptor 1 |
| HELZ | helicase with zinc finger |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IL15RA | interleukin 15 receptor, alpha |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCRS1 | microspherule protein 1 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MX1 | MX dynamin-like GTPase 1 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NRTN | neurturin |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PC | pyruvate carboxylase |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POLH | polymerase (DNA directed), eta |
| PTK6 | protein tyrosine kinase 6 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPGR | retinitis pigmentosa GTPase regulator |
| SAMHD1 | SAM domain and HD domain 1 |
| SIRT2 | sirtuin 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| STAG3 | stromal antigen 3 |
| STIM1 | stromal interaction molecule 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| THBS3 | thrombospondin 3 |
| TLN1 | talin 1 |
| TMEM242 | transmembrane protein 242 |
| TMEM40 | transmembrane protein 40 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOM1 | target of myb1 (chicken) |
| TOR4A | torsin family 4, member A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TSC22D4 | TSC22 domain family, member 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VASP | vasodilator-stimulated phosphoprotein |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF574 | zinc finger protein 574 |
| ZNF747 | zinc finger protein 747 |
