| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the todralazine-1841 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTN2 | actinin, alpha 2 |
| ACVR1B | activin A receptor, type IB |
| ADA | adenosine deaminase |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AMT | aminomethyltransferase |
| ANO10 | anoctamin 10 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| APOE | apolipoprotein E |
| ASGR2 | asialoglycoprotein receptor 2 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| BBS4 | Bardet-Biedl syndrome 4 |
| BCORL1 | BCL6 corepressor-like 1 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CEP164 | centrosomal protein 164kDa |
| CHPF | chondroitin polymerizing factor |
| COG4 | component of oligomeric golgi complex 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EFNB3 | ephrin-B3 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| ENO3 | enolase 3 (beta, muscle) |
| EPHB6 | EPH receptor B6 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FGF6 | fibroblast growth factor 6 |
| FGL1 | fibrinogen-like 1 |
| FOSL2 | FOS-like antigen 2 |
| FTCD | formimidoyltransferase cyclodeaminase |
| GK3P | glycerol kinase 3 pseudogene |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC7 | histone deacetylase 7 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HOXC8 | homeobox C8 |
| ICAM2 | intercellular adhesion molecule 2 |
| IFT122 | intraflagellar transport 122 |
| KCNN3 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LOC729164 | hCG1732469 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MIIP | migration and invasion inhibitory protein |
| MLH3 | mutL homolog 3 |
| MMP25 | matrix metallopeptidase 25 |
| MPZL1 | myelin protein zero-like 1 |
| MYT1 | myelin transcription factor 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCOA1 | nuclear receptor coactivator 1 |
| NCOA2 | nuclear receptor coactivator 2 |
| NCOA3 | nuclear receptor coactivator 3 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NRP1 | neuropilin 1 |
| NUMB | numb homolog (Drosophila) |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLCB4 | phospholipase C, beta 4 |
| PLXNA1 | plexin A1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PRDX2 | peroxiredoxin 2 |
| RAP1GAP | RAP1 GTPase activating protein |
| REST | RE1-silencing transcription factor |
| RET | ret proto-oncogene |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SFTPC | surfactant protein C |
| SH2D4A | SH2 domain containing 4A |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC38A7 | solute carrier family 38, member 7 |
| SMAD1 | SMAD family member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TADA3 | transcriptional adaptor 3 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| TDRD3 | tudor domain containing 3 |
| TFEB | transcription factor EB |
| TMEM80 | transmembrane protein 80 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRBC1 | T cell receptor beta constant 1 |
| TSPYL2 | TSPY-like 2 |
| USB1 | U6 snRNA biogenesis 1 |
| UTS2 | urotensin 2 |
| WDR4 | WD repeat domain 4 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| Symbol | Name |
|---|---|
| ACAD8 | acyl-CoA dehydrogenase family, member 8 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKRD55 | ankyrin repeat domain 55 |
| ATG2B | autophagy related 2B |
| BCL2L2 | BCL2-like 2 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C1ORF109 | chromosome 1 open reading frame 109 |
| CCDC109B | coiled-coil domain containing 109B |
| CCNJ | cyclin J |
| CD37 | CD37 molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDK9 | cyclin-dependent kinase 9 |
| CENPT | centromere protein T |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLDN15 | claudin 15 |
| CORO2A | coronin, actin binding protein, 2A |
| CREB3 | cAMP responsive element binding protein 3 |
| DYM | dymeclin |
| ECD | ecdysoneless homolog (Drosophila) |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FKTN | fukutin |
| FPGS | folylpolyglutamate synthase |
| GALE | UDP-galactose-4-epimerase |
| GALT | galactose-1-phosphate uridylyltransferase |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSF2 | heat shock transcription factor 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| KIF18A | kinesin family member 18A |
| LXN | latexin |
| LYRM2 | LYR motif containing 2 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MED4 | mediator complex subunit 4 |
| METTL8 | methyltransferase like 8 |
| MON1B | MON1 secretory trafficking family member B |
| MOSPD1 | motile sperm domain containing 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYBBP1A | MYB binding protein (P160) 1a |
| MYNN | myoneurin |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OCEL1 | occludin/ELL domain containing 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PANK4 | pantothenate kinase 4 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PROSER1 | proline and serine rich 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RNASE6 | ribonuclease, RNase A family, k6 |
| SAR1B | secretion associated, Ras related GTPase 1B |
| SETD6 | SET domain containing 6 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SLC35A5 | solute carrier family 35, member A5 |
| SNX10 | sorting nexin 10 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPP1 | secreted phosphoprotein 1 |
| SRRD | SRR1 domain containing |
| STAR | steroidogenic acute regulatory protein |
| STK25 | serine/threonine kinase 25 |
| SYNGR2 | synaptogyrin 2 |
| THOP1 | thimet oligopeptidase 1 |
| TLN1 | talin 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM106B | transmembrane protein 106B |
| TMEM186 | transmembrane protein 186 |
| TRAC | T cell receptor alpha constant |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTF2 | transcription termination factor, RNA polymerase II |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UBXN6 | UBX domain protein 6 |
| UFSP2 | UFM1-specific peptidase 2 |
| USP11 | ubiquitin specific peptidase 11 |
| VPS37C | vacuolar protein sorting 37 homolog C (S. cerevisiae) |
| XAF1 | XIAP associated factor 1 |
| YIPF3 | Yip1 domain family, member 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF302 | zinc finger protein 302 |
| ZNF331 | zinc finger protein 331 |
| ZNF574 | zinc finger protein 574 |
| ZNF654 | zinc finger protein 654 |
| ZNF669 | zinc finger protein 669 |
| ZNF675 | zinc finger protein 675 |
