| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the todralazine-5087 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACVR1B | activin A receptor, type IB |
| ADCY1 | adenylate cyclase 1 (brain) |
| AFF1 | AF4/FMR2 family, member 1 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| ALPK1 | alpha-kinase 1 |
| ATP11A | ATPase, class VI, type 11A |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1S | complement component 1, s subcomponent |
| CACNG2 | calcium channel, voltage-dependent, gamma subunit 2 |
| CCDC7 | coiled-coil domain containing 7 |
| CCNJL | cyclin J-like |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CREB5 | cAMP responsive element binding protein 5 |
| CRH | corticotropin releasing hormone |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| DST | dystonin |
| EFNB1 | ephrin-B1 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FOXN3 | forkhead box N3 |
| GLI2 | GLI family zinc finger 2 |
| GRAMD1C | GRAM domain containing 1C |
| GYG2 | glycogenin 2 |
| HOXC11 | homeobox C11 |
| HPR | haptoglobin-related protein |
| HS6ST1 | heparan sulfate 6-O-sulfotransferase 1 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| IMPG2 | interphotoreceptor matrix proteoglycan 2 |
| KIAA1456 | KIAA1456 |
| LATS1 | large tumor suppressor kinase 1 |
| LEFTY2 | left-right determination factor 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LRP1 | low density lipoprotein receptor-related protein 1 |
| LRRC1 | leucine rich repeat containing 1 |
| LRRC75B | leucine rich repeat containing 75B |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MIIP | migration and invasion inhibitory protein |
| MRC2 | mannose receptor, C type 2 |
| MUSK | muscle, skeletal, receptor tyrosine kinase |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRO2964 | uncharacterized protein PRO2964 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RPL7 | ribosomal protein L7 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SH2D3A | SH2 domain containing 3A |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC9A3 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPHK2 | sphingosine kinase 2 |
| SPRR1A | small proline-rich protein 1A |
| STRN | striatin, calmodulin binding protein |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) |
| TFAP2B | transcription factor AP-2 beta (activating enhancer binding protein 2 beta) |
| TGFB1 | transforming growth factor, beta 1 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM63A | transmembrane protein 63A |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VSNL1 | visinin-like 1 |
| XYLT2 | xylosyltransferase II |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZER1 | zyg-11 related, cell cycle regulator |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| AKTIP | AKT interacting protein |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| BAK1 | BCL2-antagonist/killer 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CAPN15 | calpain 15 |
| CARD8 | caspase recruitment domain family, member 8 |
| CDK6 | cyclin-dependent kinase 6 |
| CENPO | centromere protein O |
| CLDN15 | claudin 15 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DLL3 | delta-like 3 (Drosophila) |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EN2 | engrailed homeobox 2 |
| ERF | Ets2 repressor factor |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FAM186A | family with sequence similarity 186, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H1E | histone cluster 1, H1e |
| HMOX1 | heme oxygenase 1 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL22 | interleukin 22 |
| IL24 | interleukin 24 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA1549L | KIAA1549-like |
| KLHL28 | kelch-like family member 28 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT86 | keratin 86, type II |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAGEF1 | melanoma antigen family F1 |
| MAP1S | microtubule-associated protein 1S |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MICALL2 | MICAL-like 2 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NDP | Norrie disease (pseudoglioma) |
| NLK | nemo-like kinase |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OSBP2 | oxysterol binding protein 2 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPL | periplakin |
| PRR14L | proline rich 14-like |
| PTK6 | protein tyrosine kinase 6 |
| QSER1 | glutamine and serine rich 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD51B | RAD51 paralog B |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RNF170 | ring finger protein 170 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A3 | S100 calcium binding protein A3 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCIN | scinderin |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLN | sarcolipin |
| TBC1D17 | TBC1 domain family, member 17 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM159 | transmembrane protein 159 |
| TRIM25 | tripartite motif containing 25 |
| TSPAN1 | tetraspanin 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF225 | zinc finger protein 225 |
| ZNF280D | zinc finger protein 280D |
| ZNF33B | zinc finger protein 33B |
| ZNF408 | zinc finger protein 408 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF74 | zinc finger protein 74 |
