| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the todralazine-5512 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABR | active BCR-related |
| ACTN2 | actinin, alpha 2 |
| ACVR1B | activin A receptor, type IB |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AHI1 | Abelson helper integration site 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| BTD | biotinidase |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAPN9 | calpain 9 |
| CD53 | CD53 molecule |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CLEC3B | C-type lectin domain family 3, member B |
| CLGN | calmegin |
| CSF1R | colony stimulating factor 1 receptor |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DCC | DCC netrin 1 receptor |
| DIRAS2 | DIRAS family, GTP-binding RAS-like 2 |
| EVPL | envoplakin |
| FCAR | Fc fragment of IgA receptor |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXB1 | forkhead box B1 |
| FRMD4A | FERM domain containing 4A |
| GM2A | GM2 ganglioside activator |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR162 | G protein-coupled receptor 162 |
| HLA-A | major histocompatibility complex, class I, A |
| HSPA12A | heat shock 70kDa protein 12A |
| IL11RA | interleukin 11 receptor, alpha |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| LEPR | leptin receptor |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LUZP1 | leucine zipper protein 1 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MBD2 | methyl-CpG binding domain protein 2 |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MPO | myeloperoxidase |
| MT1F | metallothionein 1F |
| MYO1E | myosin IE |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NBEAL2 | neurobeachin-like 2 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NDRG2 | NDRG family member 2 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NLGN3 | neuroligin 3 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NUP214 | nucleoporin 214kDa |
| OR7A17 | olfactory receptor, family 7, subfamily A, member 17 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKCB | protein kinase C, beta |
| PXDC1 | PX domain containing 1 |
| QKI | QKI, KH domain containing, RNA binding |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RUNDC3A | RUN domain containing 3A |
| SCAMP1 | secretory carrier membrane protein 1 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC43A3 | solute carrier family 43, member 3 |
| SLN | sarcolipin |
| SNCAIP | synuclein, alpha interacting protein |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STK24 | serine/threonine kinase 24 |
| STRN3 | striatin, calmodulin binding protein 3 |
| STX7 | syntaxin 7 |
| TADA3 | transcriptional adaptor 3 |
| TBC1D13 | TBC1 domain family, member 13 |
| TBC1D22A | TBC1 domain family, member 22A |
| TK2 | thymidine kinase 2, mitochondrial |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TRIM29 | tripartite motif containing 29 |
| ULBP1 | UL16 binding protein 1 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| WIZ | widely interspaced zinc finger motifs |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF345 | zinc finger protein 345 |
| ZNF778 | zinc finger protein 778 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BAGE | B melanoma antigen |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN5 | calpain 5 |
| CAPRIN2 | caprin family member 2 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CES3 | carboxylesterase 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CIC | capicua transcriptional repressor |
| CORT | cortistatin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| F2R | coagulation factor II (thrombin) receptor |
| FHOD1 | formin homology 2 domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BF | histone cluster 1, H2bf |
| HMOX1 | heme oxygenase 1 |
| HOXC10 | homeobox C10 |
| HPSE | heparanase |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA2 | heat shock 70kDa protein 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIAA0894 | KIAA0894 protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAPK3 | mitogen-activated protein kinase 3 |
| MICALL2 | MICAL-like 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NABP2 | nucleic acid binding protein 2 |
| NAV2 | neuron navigator 2 |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOL12 | nucleolar protein 12 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUBPL | nucleotide binding protein-like |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OLFML3 | olfactomedin-like 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRPH | peripherin |
| PTK6 | protein tyrosine kinase 6 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF43 | ring finger protein 43 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RRP1 | ribosomal RNA processing 1 |
| RWDD3 | RWD domain containing 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SP140L | SP140 nuclear body protein-like |
| SYCP2 | synaptonemal complex protein 2 |
| TAGLN | transgelin |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TUBA3C | tubulin, alpha 3c |
| TUBA3D | tubulin, alpha 3d |
| UBQLN4 | ubiquilin 4 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZNF408 | zinc finger protein 408 |
| ZNF586 | zinc finger protein 586 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
