| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the tolazamide-2482 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10A | ATPase, class V, type 10A |
| BARX1 | BARX homeobox 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CABP1 | calcium binding protein 1 |
| CAPN9 | calpain 9 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDC14B | cell division cycle 14B |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CIB2 | calcium and integrin binding family member 2 |
| CLMN | calmin (calponin-like, transmembrane) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| DAPK3 | death-associated protein kinase 3 |
| DFNB31 | deafness, autosomal recessive 31 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| EPS8L1 | EPS8-like 1 |
| EXOSC2 | exosome component 2 |
| FGB | fibrinogen beta chain |
| FN1 | fibronectin 1 |
| FRMD4B | FERM domain containing 4B |
| GK2 | glycerol kinase 2 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GPR107 | G protein-coupled receptor 107 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GTDC1 | glycosyltransferase-like domain containing 1 |
| HIST1H4A | histone cluster 1, H4a |
| IL5RA | interleukin 5 receptor, alpha |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LEFTY1 | left-right determination factor 1 |
| LENEP | lens epithelial protein |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MAL | mal, T-cell differentiation protein |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED25 | mediator complex subunit 25 |
| MLXIPL | MLX interacting protein-like |
| MYO6 | myosin VI |
| NCKAP1L | NCK-associated protein 1-like |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEUROD1 | neuronal differentiation 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFML2B | olfactomedin-like 2B |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCYT1B | phosphate cytidylyltransferase 1, choline, beta |
| PDCD6 | programmed cell death 6 |
| PDE11A | phosphodiesterase 11A |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHF3 | PHD finger protein 3 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PRPH | peripherin |
| PSG1 | pregnancy specific beta-1-glycoprotein 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RANBP1 | RAN binding protein 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RGS3 | regulator of G-protein signaling 3 |
| RPL10 | ribosomal protein L10 |
| RPL7 | ribosomal protein L7 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SH2D3A | SH2 domain containing 3A |
| SIRPA | signal-regulatory protein alpha |
| SIRT4 | sirtuin 4 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLN | sarcolipin |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSH3 | slingshot protein phosphatase 3 |
| STAB1 | stabilin 1 |
| TAGLN3 | transgelin 3 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBCD | tubulin folding cofactor D |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEF | thyrotrophic embryonic factor |
| THBD | thrombomodulin |
| TNNT3 | troponin T type 3 (skeletal, fast) |
| TRGV5 | T cell receptor gamma variable 5 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| WDR25 | WD repeat domain 25 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKRD55 | ankyrin repeat domain 55 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| APOO | apolipoprotein O |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C12ORF49 | chromosome 12 open reading frame 49 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCDC47 | coiled-coil domain containing 47 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLSPN | claspin |
| CRY2 | cryptochrome circadian clock 2 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EFNA3 | ephrin-A3 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FLCN | folliculin |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GK3P | glycerol kinase 3 pseudogene |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPR63 | G protein-coupled receptor 63 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL11RA | interleukin 11 receptor, alpha |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MBTD1 | mbt domain containing 1 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP9 | matrix metallopeptidase 9 |
| MREG | melanoregulin |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PGM3 | phosphoglucomutase 3 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PLCD1 | phospholipase C, delta 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PRR7 | proline rich 7 (synaptic) |
| RAB23 | RAB23, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF122 | ring finger protein 122 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD3 | RWD domain containing 3 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPAG1 | sperm associated antigen 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK4 | serine/threonine kinase 4 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D19 | TBC1 domain family, member 19 |
| TEC | tec protein tyrosine kinase |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMEM209 | transmembrane protein 209 |
| TOLLIP | toll interacting protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| YY2 | YY2 transcription factor |
| ZNF134 | zinc finger protein 134 |
| ZNF273 | zinc finger protein 273 |
| ZNF345 | zinc finger protein 345 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF428 | zinc finger protein 428 |
| ZNF480 | zinc finger protein 480 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |