| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tolazamide-2842 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACVR1B | activin A receptor, type IB |
| AGFG1 | ArfGAP with FG repeats 1 |
| ALPK1 | alpha-kinase 1 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ATF7IP | activating transcription factor 7 interacting protein |
| ATM | ATM serine/threonine kinase |
| ATP11A | ATPase, class VI, type 11A |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BMP8B | bone morphogenetic protein 8b |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CA4 | carbonic anhydrase IV |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CBX8 | chromobox homolog 8 |
| CCDC9 | coiled-coil domain containing 9 |
| CERS4 | ceramide synthase 4 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| COL11A2 | collagen, type XI, alpha 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DMXL2 | Dmx-like 2 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ETV5 | ets variant 5 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLCN | folliculin |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRM1 | glutamate receptor, metabotropic 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL6ST | interleukin 6 signal transducer |
| JUN | jun proto-oncogene |
| KIAA0125 | KIAA0125 |
| KLHL22 | kelch-like family member 22 |
| KLHL24 | kelch-like family member 24 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOC729164 | hCG1732469 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAX | MYC associated factor X |
| MCC | mutated in colorectal cancers |
| MED18 | mediator complex subunit 18 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MTCP1 | mature T-cell proliferation 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NCOA2 | nuclear receptor coactivator 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PAX5 | paired box 5 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PVR | poliovirus receptor |
| RAB6B | RAB6B, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBPMS | RNA binding protein with multiple splicing |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNFT1 | ring finger protein, transmembrane 1 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SETD2 | SET domain containing 2 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SIDT2 | SID1 transmembrane family, member 2 |
| SMAD5 | SMAD family member 5 |
| SRRT | serrate, RNA effector molecule |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYMPK | symplekin |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TBC1D30 | TBC1 domain family, member 30 |
| TEP1 | telomerase-associated protein 1 |
| TGM2 | transglutaminase 2 |
| TMC6 | transmembrane channel-like 6 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UBQLN4 | ubiquilin 4 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| WDR76 | WD repeat domain 76 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF41 | zinc finger protein 41 |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BBC3 | BCL2 binding component 3 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C5AR2 | complement component 5a receptor 2 |
| CA11 | carbonic anhydrase XI |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDK3 | cyclin-dependent kinase 3 |
| CEP72 | centrosomal protein 72kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CIC | capicua transcriptional repressor |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EVPL | envoplakin |
| FAM155B | family with sequence similarity 155, member B |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FCHO1 | FCH domain only 1 |
| FOXI1 | forkhead box I1 |
| FUZ | fuzzy planar cell polarity protein |
| GALK1 | galactokinase 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GK3P | glycerol kinase 3 pseudogene |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD4 | GRAM domain containing 4 |
| HIST1H4D | histone cluster 1, H4d |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IREB2 | iron-responsive element binding protein 2 |
| IRF1 | interferon regulatory factor 1 |
| JMJD4 | jumonji domain containing 4 |
| KCTD2 | potassium channel tetramerization domain containing 2 |
| KIAA0513 | KIAA0513 |
| KLHL25 | kelch-like family member 25 |
| KLK5 | kallikrein-related peptidase 5 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LYRM9 | LYR motif containing 9 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| METTL16 | methyltransferase like 16 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOSPD3 | motile sperm domain containing 3 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MVP | major vault protein |
| MYO1E | myosin IE |
| NLRX1 | NLR family member X1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OLFML2A | olfactomedin-like 2A |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLA2G3 | phospholipase A2, group III |
| PLD3 | phospholipase D family, member 3 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PRPH | peripherin |
| PRSS22 | protease, serine, 22 |
| RAB30 | RAB30, member RAS oncogene family |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SHROOM2 | shroom family member 2 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TCTN2 | tectonic family member 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM209 | transmembrane protein 209 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM66 | tripartite motif containing 66 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC33 | tetratricopeptide repeat domain 33 |
| VEGFC | vascular endothelial growth factor C |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR18 | WD repeat domain 18 |
| WDR33 | WD repeat domain 33 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF606 | zinc finger protein 606 |
| ZNF639 | zinc finger protein 639 |
