| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tolazoline-1500 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY1 | adenylate cyclase 1 (brain) |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| AIM1L | absent in melanoma 1-like |
| AK1 | adenylate kinase 1 |
| ALPK1 | alpha-kinase 1 |
| AMT | aminomethyltransferase |
| ATG3 | autophagy related 3 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BAIAP3 | BAI1-associated protein 3 |
| BRCA2 | breast cancer 2, early onset |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA9 | carbonic anhydrase IX |
| CFAP44 | cilia and flagella associated protein 44 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CUL7 | cullin 7 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DEAF1 | DEAF1 transcription factor |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DSC2 | desmocollin 2 |
| EDNRA | endothelin receptor type A |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EGR1 | early growth response 1 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EZR | ezrin |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FLJ42627 | uncharacterized LOC645644 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GK3P | glycerol kinase 3 pseudogene |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR176 | G protein-coupled receptor 176 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIST1H2AL | histone cluster 1, H2al |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMAN1 | lectin, mannose-binding, 1 |
| LYST | lysosomal trafficking regulator |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MED18 | mediator complex subunit 18 |
| MED25 | mediator complex subunit 25 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFSD7 | major facilitator superfamily domain containing 7 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MTMR2 | myotubularin related protein 2 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NMT2 | N-myristoyltransferase 2 |
| NPPA | natriuretic peptide A |
| NYNRIN | NYN domain and retroviral integrase containing |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLIN2 | perilipin 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTN | pleiotrophin |
| PVRL3 | poliovirus receptor-related 3 |
| RBFA | ribosome binding factor A (putative) |
| RPL35A | ribosomal protein L35a |
| SAFB | scaffold attachment factor B |
| SH2B1 | SH2B adaptor protein 1 |
| SIRT5 | sirtuin 5 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TAOK2 | TAO kinase 2 |
| TLE2 | transducin-like enhancer of split 2 |
| TLR5 | toll-like receptor 5 |
| TMEM80 | transmembrane protein 80 |
| TRIM2 | tripartite motif containing 2 |
| TUBA3C | tubulin, alpha 3c |
| UROD | uroporphyrinogen decarboxylase |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF484 | zinc finger protein 484 |
| ZNF701 | zinc finger protein 701 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADTRP | androgen-dependent TFPI-regulating protein |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARRB1 | arrestin, beta 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC9 | coiled-coil domain containing 9 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CST6 | cystatin E/M |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EPHA2 | EPH receptor A2 |
| EPN2 | epsin 2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FUZ | fuzzy planar cell polarity protein |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GPR87 | G protein-coupled receptor 87 |
| GPX2 | glutathione peroxidase 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H2BF | histone cluster 1, H2bf |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI35 | interferon-induced protein 35 |
| IL22 | interleukin 22 |
| INADL | InaD-like (Drosophila) |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF2 | interferon regulatory factor 2 |
| KLHL25 | kelch-like family member 25 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMBR1L | limb development membrane protein 1-like |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MFAP2 | microfibrillar-associated protein 2 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYH9 | myosin, heavy chain 9, non-muscle |
| NKX3-2 | NK3 homeobox 2 |
| OLFML2A | olfactomedin-like 2A |
| PCDHA6 | protocadherin alpha 6 |
| PCDHA9 | protocadherin alpha 9 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNA3 | plexin A3 |
| PMP22 | peripheral myelin protein 22 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| QSER1 | glutamine and serine rich 1 |
| RBL1 | retinoblastoma-like 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RNF39 | ring finger protein 39 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| RSRC1 | arginine/serine-rich coiled-coil 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SNHG3 | small nucleolar RNA host gene 3 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SNX15 | sorting nexin 15 |
| SP1 | Sp1 transcription factor |
| SPAG4 | sperm associated antigen 4 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TESK2 | testis-specific kinase 2 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TNS3 | tensin 3 |
| TRABD | TraB domain containing |
| UBQLN4 | ubiquilin 4 |
| UNC119 | unc-119 homolog (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WDR25 | WD repeat domain 25 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF33B | zinc finger protein 33B |
| ZNF34 | zinc finger protein 34 |
| ZNF423 | zinc finger protein 423 |
| ZNF665 | zinc finger protein 665 |
| ZNF8 | zinc finger protein 8 |
